PRODUCT REVIEW
Pacifica Wake Up Beautiful Microneedling Patches
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What can the product work for?
Anti-aging
What does the product description say?
Place between brows, over crow’s feet or smile lines.
hydroxypinacolone retinoate
0.15% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
adenosine
0.55% -
1.25%
Irritation risk:
Concentration: Effectiveness: HIGH
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
madecassoside
1.1% -
1.6%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Moisturizing
What does the product description say?
Each needle is infused with concentrated Granactive Retinoid and hyaluronic acid, our secret formula in the fight against visible signs of aging.
madecassoside
1.1% -
1.6%
Irritation risk:
Concentration: Effectiveness: HIGH
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
sodium hyaluronate
3.7% -
5.5%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
trehalose
4.8% -
7.2%
Irritation risk:
Concentration: Effectiveness: HIGH
A sugar that attracts water to the upper layer of the skin
Show more
Anti-blemish
hydroxypinacolone retinoate
0.15% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
Evens skin tone
hydroxypinacolone retinoate
0.15% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
madecassoside
1.1% -
1.6%
Irritation risk:
Concentration: Effectiveness:
LOW
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Anti-oxidation
madecassoside
1.1% -
1.6%
Irritation risk:
Concentration: Effectiveness: HIGH
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
adenosine
0.55% -
1.25%
Irritation risk:
Concentration: Effectiveness:
LOW
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 0
Potential irritants
hydroxypinacolone retinoate
0.15% -
0.55%
Irritation risk:
Works for:
Evens skin tone,
Anti-aging,
Anti-blemish,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
madecassoside
1.1% -
1.6%
Irritation risk:
Works for:
Anti-oxidation,
Moisturizing,
Anti-aging,
Evens skin tone
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Show more
Comodogenic ingredients
No comodogenic ingredients detected
User reviews (0)
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| Price | |||||||||||
| WIMJ similarity score |
66%
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42%
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41%
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41%
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40%
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40%
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38%
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37%
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36%
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33%
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| Key ingredients | Common:
Other:
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| Irritancy | IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
HIGH
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
LOW
| IRRITANCY
MEDIUM
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Ingredients & concentrations
All ingredients
Key Actives
hydroxypinacolone retinoate
0.15% -
0.55%
Irritation risk:
Works for:
Evens skin tone,
Anti-aging,
Anti-blemish,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
madecassoside
1.1% -
1.6%
Irritation risk:
Works for:
Anti-oxidation,
Moisturizing,
Anti-aging,
Evens skin tone
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Show more
Potential irritants
hydroxypinacolone retinoate
0.15% -
0.55%
Irritation risk:
Works for:
Evens skin tone,
Anti-aging,
Anti-blemish,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
madecassoside
1.1% -
1.6%
Irritation risk:
Works for:
Anti-oxidation,
Moisturizing,
Anti-aging,
Evens skin tone
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Show more
Comodogenic ingredients
We couldn't find any comodogenic ingredients in this product
All ingredients
hydrolyzed hyaluronic acid
23% -
34%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
glycerin
6.4% -
9.6%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
trehalose
4.8% -
7.2%
Irritation risk:
Works for:
Moisturizing
A sugar that attracts water to the upper layer of the skin
Show more
Ingredient list view
Hydrolyzed hyaluronic acid, Glycerin, Trehalose, Sodium hyaluronate, Dimethyl isosorbide, Hydroxypinacolone retinoate, Madecassoside, Adenosine, Polyglyceryl-10 laurate
Sources
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Glycerol and the skin: holistic approach to its origin and functions
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- Antiaging effects of retinoid hydroxypinacolone retinoate on skin models. (2018). Journal of the American Academy of Dermatology, 79(3), AB44. doi:10.1016/j.jaad.2018.05.215
- Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
- Centella asiatica in Dermatology: An Overview
- Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytes
- Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress
- Madecassoside Inhibits Melanin Synthesis by Blocking Ultraviolet-Induced Inflammation
- Contact dermatitis due to Madecassol
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Stability Study of the Active Constituents in the Centella asiatica Extract Formulations
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique