Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
- Anti-blemish
Can it cause trouble?
- Irritation risk: low
- Comedogenic risk ingredients: 2
Key actives
Product Summary
Based on the ingredient list, "Orjena - Response synergy barrier cream" can work well for skin moisturization. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Panthenol, betaine, glycerin, sodium hyaluronate and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Caprylic/capric triglyceride, dimethicone, cetearyl alcohol, ethylhexyl palmitate and caprylyl glycol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- We like that this moisturizer contains peptides (sh-polypeptide-9 0.10% - 0.20%, sh-polypeptide-11 0.15% - 0.25%, sh-oligopeptide-2 0.15% - 0.30%, sh-polypeptide-1 0.20% - 0.35% and sh-oligopeptide-1 0.20% - 0.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.50% - 0.70%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
- Panthenol (pro-vitamin B5) at about 5.60% - 6.80% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
Irritation risk
This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-aging
What does the product description say?
This cream offers excellent protection and care for the skin barrier, while also being effective against wrinkles.
Source: N/A
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11, sh-polypeptide-9.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
What does the product description say?
Response synergy barrier cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
betaine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol, sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11, sh-polypeptide-9
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin and improves the product texture
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A "broth" with parts of dead cells of lactobacteria. Might be helpful supporting diverse microbiome in skin, but evidence is lacking
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An emollient that helps soften the skin and create a nice product texture
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps preserve products and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score: 100/100.
We receive a small commission for purchases made through these links at no cost for you. Thank you for your support! Learn more
Potential irritants
Comedogenic ingredients
User reviews (0)
Averages from community submissions.
No reviews yet for this product.
Be the first to share your experience!
Tried this product?
Help capture what the ingredient list can't—texture, finish, pilling, scent, and more. Answer what you can, skip the rest.
Takes ~30 seconds.
Reviews are shown in aggregate. No personal details.
| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Orjena Response synergy barrier cream | Current | $25.00 | |
 LABIOTTE Aesthe RX Collagen Cream | 76% | $66.00 | |
APLB Premium Mens Homme Moisture Cream | 75% | $24.00 | |
 MEDI-PEEL Buy Medipeel Melanon X Cream Australia - Korean Skin Care and Cosmetics | 74% | $26.00 | |
Manyo Galactomy Essence Cream | 73% | $17.90 | |
Klairs Midnight Blue Clearing Water Cream | 72% | - |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Helps attract water to the upper layer of the skin and improves the product texture
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Potential irritants
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Helps preserve products and creates a nice product texture
Comedogenic ingredients
An emollient that helps soften the skin and create a nice product texture
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
All ingredients
Helps attract water to the upper layer of the skin and can help improve skin barrier function
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
An emollient that helps soften the skin and create a nice product texture
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Helps attract water to the upper layer of the skin and improves the product texture
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
A "broth" with parts of dead cells of lactobacteria. Might be helpful supporting diverse microbiome in skin, but evidence is lacking
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps preserve products and creates a nice product texture
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Ingredient list view
Water, Panthenol, Glycerin, Caprylic/capric triglyceride, Ethylhexyl palmitate, Polyglyceryl-3 methylglucose distearate, 1,2-hexanediol, Niacinamide, Cetearyl alcohol, Dimethicone, Cetearyl olivate, Sorbitan olivate, Glyceryl stearate, Tromethamine, Carbomer, Betaine, Adenosine, Disodium edta, Butylene glycol, Lecithin, Acetyl glutamine, Lactococcus ferment extract, Bifida ferment extract, Lactobacillus ferment lysate, Sodium hyaluronate, Caprylyl glycol, Sh-oligopeptide-1, Sh-polypeptide-1, Sh-oligopeptide-2, Sh-polypeptide-11, Sh-polypeptide-9, Bacillus/folic acid/soybean ferment extract, Ethylhexylglycerin
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety Assessment of Tromethamine as Used in Cosmetics
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care