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Obagi 360 Retinol 0.5
Obagi

Obagi 360 Retinol 0.5

Efficacy93/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Retinol, Butyrospermum parkii butter + 2 more
Works well
What the product description says
“A lower concentration of 0.5% retinol boosts cell turnover to minimize acne, fine lines and wrinkles while diminishing hyperpigmentation.”
Source: Dermstore

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–0.75%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.8–2.1%
UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.2–0.35%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.35%
Anti-blemish
Retinol
Works well
What the product description says
“A lower concentration of 0.5% retinol boosts cell turnover to minimize acne, fine lines and wrinkles while diminishing hyperpigmentation.”
Source: Dermstore

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–0.75%
Evens skin tone
Retinol, Dipotassium glycyrrhizate + 1 more
Works well
What the product description says
“Retinol 0.5 gradually releases retinol, refining the appearance of skin texture and tone for clearer-looking skin.”
Source: Skinstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–0.75%
Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.35%
Moisturizing
Caprylic/capric triglyceride, Cyclopentasiloxane + 15 more
Works
What the product description says
“Hydrating jojoba oil and shea butter promote firmness and elasticity as vitamins C and E work synergistically to neutralize free radicals.”
Source: Dermstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glyceryl acrylate/acrylic acid copolymer.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.5–7.9%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~3.2–3.9%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.8–2.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1–1.2%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.5–0.75%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.35%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.2–0.35%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.15–0.3%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~3.6–4.4%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.4–2.9%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.1–2.5%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.2–0.4%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.15–0.3%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.3%
CyclohexasiloxaneEffect: Low, below effective doseA silicone that serves as an emollient. Helps create a nice non-greasy feels~0.25–0.5%
Simmondsia chinensis seed oilUnder-dosedSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.45–0.65%
Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%
Anti-oxidation
Side benefit · Retinol, Ubiquinone + 6 more
Works well

This product contains antioxidants (retinol, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–0.75%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.2–0.35%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.8–2.1%
Malva sylvestris flower extractEffect: LowUsed as a fragrance~0.3–0.55%
Sambucus nigra flower extractEffect: LowA plant extract that might help neutralize free radicals in skin~0.2–0.4%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.2–0.35%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.15–0.25%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.35%
Exfoliation
Side benefit · Retinol
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–0.75%

Can it cause trouble?

Irritancy
3 strong irritants: Retinol, Malva sylvestris flower extract + 1 more — patch-test recommended
High risk
We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.5–0.75%est.
Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.35–0.6%est.
Malva sylvestris flower extractUsed as a fragranceHigh~0.3–0.55%est.
Salvia officinalis leaf extractSage leaf extract. It can be irritatingHigh~0.3–0.55%est.
Sambucus nigra flower extractA plant extract that might help neutralize free radicals in skinHigh~0.2–0.4%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.2–0.35%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.15–0.3%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.5–7.9%est.
Polysorbate 60Helps oil and water mix togetherMedium~1.5–1.8%est.
Allyl methacrylates crosspolymerUsed to stabilize product formulationsMedium~0.75–1.1%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.45–0.65%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.2–0.35%est.
BhtA preservativeMedium~0.15–0.3%est.
Disodium edtaStabilizes the product formulationMedium~0.15–0.3%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.2–0.35%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.15–0.3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.3%est.
EthylhexylglycerinA preservativeMedium~0.1–0.2%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.1–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.8–2.1%est.
Alternatives
Cheaper, or higher on efficacy
Age Intervention Retinol Plus
Jan Marini Age Intervention Retinol Plus
Higher efficacy · 100/10095% match
$107.61
Retinol Expert 0.3%
IOPE Retinol Expert 0.3%
CheaperHigher efficacy · 100/10087% match
$79.00
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.5–7.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glyceryl stearate~3.6–4.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Cyclopentasiloxane~3.2–3.9%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Butylene glycol~2.4–2.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Stearic acid~2.1–2.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Butyrospermum parkii butter~1.8–2.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Polysorbate 60~1.5–1.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Stearyl alcohol~1.3–1.6%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Glycerin~1–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Allyl methacrylates crosspolymer~0.75–1.1%
Irritant · medium
Irritation risk
Medium

Used to stabilize product formulations

More about Allyl methacrylates crosspolymer
Retinol~0.5–0.75%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-blemishMattifyingExfoliationAnti-oxidation

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Polysorbate 20~0.5–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Dimethicone~0.5–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Simmondsia chinensis seed oil~0.45–0.65%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Chamomilla recutita flower extract~0.35–0.6%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract
Hypericum perforatum flower extract~0.3–0.6%
Formula
Irritation risk
Low
More about Hypericum perforatum flower extract
Malva sylvestris flower extract~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Used as a fragrance

More about Malva sylvestris flower extract
Salvia officinalis leaf extract~0.3–0.55%
Irritant · high
Irritation risk
High

Sage leaf extract. It can be irritating

More about Salvia officinalis leaf extract
Sambucus nigra flower extract~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

A plant extract that might help neutralize free radicals in skin

More about Sambucus nigra flower extract
Cyclohexasiloxane~0.25–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Sorbitol~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Tocopheryl acetate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ascorbic acid~0.2–0.35%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Ubiquinone~0.2–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Sodium hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Propylene glycol~0.15–0.3%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Bht~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Bisabolol~0.15–0.25%
Formula
Irritation risk
Low
Works for
Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Dimethicone/vinyl dimethicone crosspolymer~0.2–0.35%
Formula
Irritation risk
Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer
Dipotassium glycyrrhizate~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Disodium edta~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Triethanolamine~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Carbomer~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Glyceryl acrylate/acrylic acid copolymer~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Caprylyl glycol~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Hexylene glycol~0.1–0.15%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Phenoxyethanol~0.1–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Caprylic/capric triglyceride, Glyceryl stearate, Cyclopentasiloxane, Butylene glycol, Stearic acid, Butyrospermum parkii butter, Polysorbate 60, Stearyl alcohol, Glycerin, Allyl methacrylates crosspolymer, Retinol, Polysorbate 20, Dimethicone, Simmondsia chinensis seed oil, Chamomilla recutita flower extract, Hypericum perforatum flower extract, Malva sylvestris flower extract, Salvia officinalis leaf extract, Sambucus nigra flower extract, Cyclohexasiloxane, Sorbitol, Tocopheryl acetate, Ascorbic acid, Ubiquinone, Sodium hyaluronate, Propylene glycol, Bht, Bisabolol, Dimethicone/vinyl dimethicone crosspolymer, Dipotassium glycyrrhizate, Disodium edta, Triethanolamine, Carbomer, Glyceryl acrylate/acrylic acid copolymer, Caprylyl glycol, Ethylhexylglycerin, Hexylene glycol, Phenoxyethanol

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Amazon USPrice as of 11/7 09:33 GMT
$80.00
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Dermstore1 oz
$80.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Obagi360 Retinol 0.5YOUR PRODUCTJan MariniAge Intervention Retinol PlusSothysCosmeceutique RX Retinol DermoboosterIOPERetinol Expert 0.3%
Match—95%88%87%
Price$80.00$107.61+$27.61—$79.00−$1.00
Shared key ingredients—9 of 136 of 136 of 13
Key difference—Palmitoyl Tetrapeptide-7Glycine Soja OilAcetyl Tetrapeptide-11
Irritancy High Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Safety Assessment of Cross-Linked Alkyl Acrylates as Used in Cosmeticsjournals.sagepub.com
  3. 3
    Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
  4. 4
    Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
  5. 5
    A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
  6. 6
    Dimethicone as a protective ingredient in topical medicationsjaad.org
Obagi 360 Retinol 0.5
Obagi360 Retinol 0.5
Buy at Dermstore$80.00$80.00as of 11/7 09:33 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Dermstore$80.00$80.00as of 11/7 09:33 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.