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Mesoestetic Dermamelan Intimate Home Depigmenting Gel Cream
Mesoestetic

Mesoestetic Dermamelan Intimate Home Depigmenting Gel Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
17 ingredients credited for this claim
Strong support
What the product description says
“Dermamelan Intimate Home Depigmenting Gel Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, mannitol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cholesterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide

PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1–1.6%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.65%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.1–0.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.3–1.9%
Helianthus annuus seed waxKey active· EmollientEffect: HighHelps soften the upper layer of the skin and support skin's barrier function while creating a thicker product consistency~0.1–0.45%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.1–0.45%
Tranexamic acidKey activeEffect: HighAn amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally~1.6–2.4%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.15–0.65%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.1–0.3%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.7–5.5%
Isostearyl alcoholKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~1.4–2.1%
Potassium azeloyl diglycinateKey activeEffect: MediumA derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture~2.7–4%
Plankton extractKey activeEffect: MediumCan help attract water to the upper layer of the skin~0.15–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2–3%
Isodecyl neopentanoate· Emollient, OcclusiveEffect: LowAn emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.~4.5–6.7%
Argania spinosa kernel oilUnder-dosedEffect: HighAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.2–0.8%
Isononyl isononanoateEffect: Low, below effective doseForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~0.5–1.1%
Evens skin tone
6 ingredients credited for this claim
Strong support
What the product description says
“This innovative home maintenance gel works by treating the mechanisms responsible for pigmentation formation, helping to prevent the appearance of dark spots and their reappearance.”
Source: Face the future

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: kojic acid, niacinamide, potassium azeloyl diglycinate, tranexamic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Tranexamic acidKey activeEffect: HighAn amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally~1.6–2.4%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.7–5.5%
Potassium azeloyl diglycinateKey activeEffect: HighA derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture~2.7–4%
Kojic acidKey activeEffect: HighHelps to reduce hyperpigmentation and neutralize free radicals. Can be irritating~0.15–0.65%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.1–0.45%
Salicylic acidEffect: Low, below effective doseUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.2–0.75%
Anti-aging
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.7–5.5%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (kojic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Kojic acidKey activeEffect: HighHelps to reduce hyperpigmentation and neutralize free radicals. Can be irritating~0.15–0.65%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.1–0.45%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.1–0.45%
Argania spinosa kernel oilEffect: Low, below effective doseAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.2–0.8%
Anti-blemish
Not advertised by the brand · 3 ingredients credited for this claim
Good support

This product might be able to help reduce blemishes and clogged pores because it contains niacinamide, potassium azeloyl diglycinate.

Potassium azeloyl diglycinateKey activeEffect: HighA derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture~2.7–4%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.7–5.5%
Salicylic acidUnder-dosedEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.2–0.75%

Can it cause trouble?

Irritancy
16 flagged ingredients
Medium risk
We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.2–0.75%est.
Kojic acidHelps to reduce hyperpigmentation and neutralize free radicals. Can be irritatingHigh~0.15–0.65%est.
Acacia decurrens flower waxUsed as a fragrance. Can be irritatingHigh~0.1–0.35%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.55–1.3%est.
Phytic acidAn alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmeticsMedium~0.35–0.85%est.
Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.2–0.8%est.
Plankton extractCan help attract water to the upper layer of the skinMedium~0.15–0.65%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.15–0.65%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.1–0.45%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.1–0.45%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.1–0.35%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.1–0.3%est.
BhtA preservativeMedium~0.1–0.3%est.
Sodium metabisulfiteA preservativeMedium~0.1–0.2%est.
Potassium sorbateA preservativeMedium~0.05–0.25%est.
EthylhexylglycerinA preservativeMedium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Plankton extractCan help attract water to the upper layer of the skin3/5~0.15–0.65%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Isodecyl neopentanoate~4.5–6.7%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.

More about Isodecyl neopentanoate
Niacinamide~3.7–5.5%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
MoisturizingAnti-blemishEvens skin toneAnti-agingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Potassium azeloyl diglycinate~2.7–4%
Key active
Irritation risk
Low
Works for
Anti-blemishAnti-inflammatoryEvens skin toneMoisturizing

A derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture

More about Potassium azeloyl diglycinate
Butylene glycol~2–3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Tranexamic acid~1.6–2.4%
Key active
Irritation risk
Low
Works for
Evens skin toneMoisturizing

An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally

More about Tranexamic acid
Isostearyl alcohol~1.4–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Isostearyl alcohol
Glycerin~1.3–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Polymethylsilsesquioxane~1–1.6%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane
Sodium citrate~0.55–1.3%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Polyacrylate
Not recognized
Isononyl isononanoate~0.5–1.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Phytic acid~0.35–0.85%
Irritant · medium
Irritation risk
Medium

An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics

More about Phytic acid
Salicylic acid~0.2–0.75%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishExfoliationAnti-inflammatoryAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Argania spinosa kernel oil~0.2–0.8%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil
Kojic acid~0.15–0.65%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin tone

Helps to reduce hyperpigmentation and neutralize free radicals. Can be irritating

More about Kojic acid
Sodium hyaluronate~0.15–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Plankton extract~0.15–0.65%
Key activeComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Can help attract water to the upper layer of the skin

More about Plankton extract
Jojoba esters~0.15–0.65%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Glycyrrhiza glabra root extract~0.1–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-inflammatoryReduces rednessEvens skin toneAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Biosaccharide gum-2~0.1–0.45%
Formula
Irritation risk
Low
More about Biosaccharide gum-2
Tocopheryl acetate~0.1–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Helianthus annuus seed wax~0.1–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and support skin's barrier function while creating a thicker product consistency

More about Helianthus annuus seed wax
Acacia decurrens flower wax~0.1–0.35%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Acacia decurrens flower wax
Phosphatidylcholine~0.1–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Citric acid~0.1–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Mannitol~0.1–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Aminoethylphosphinic acid~0.1–0.3%
Formula
Irritation risk
Low

Used to stabilize the product formulation

More about Aminoethylphosphinic acid
Cholesterol~0.1–0.45%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Polysorbate 80~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Sodium chloride~0.1–0.4%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Polyisobutene~0.1–0.4%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Polyacrylate-13~0.1–0.4%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13
Sodium hydroxide~0.1–0.35%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Ethylcellulose~0.1–0.35%
Formula
Irritation risk
Low
More about Ethylcellulose
Bht~0.1–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Sodium metabisulfite~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sodium metabisulfite
Dimethicone~0.1–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Potassium sorbate~0.05–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium benzoate~0.05–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ethylhexylglycerin~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Phenoxyethanol~0.05–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Isodecyl neopentanoate, Niacinamide, Potassium azeloyl diglycinate, Butylene glycol, Tranexamic acid, Isostearyl alcohol, Glycerin, Polymethylsilsesquioxane, Sodium citrate, Unknown, Isononyl isononanoate, Phytic acid, Salicylic acid, Argania spinosa kernel oil, Kojic acid, Sodium hyaluronate, Plankton extract, Jojoba esters, Glycyrrhiza glabra root extract, Biosaccharide gum-2, Tocopheryl acetate, Helianthus annuus seed wax, Acacia decurrens flower wax, Phosphatidylcholine, Citric acid, Mannitol, Aminoethylphosphinic acid, Cholesterol, Polysorbate 80, Sodium chloride, Polyisobutene, Polyacrylate-13, Sodium hydroxide, Ethylcellulose, Bht, Sodium metabisulfite, Dimethicone, Potassium sorbate, Sodium benzoate, Ethylhexylglycerin, Phenoxyethanol

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Face the future
≈ $112.36
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MesoesteticDermamelan Intimate Home Depigmenting Gel CreamYOUR PRODUCTBiodermaHydrabio Gel-CremePaula's choiceInvisible Finish Moisture Gele.l.f. CosmeticsBlemish Breakthrough Blemish Calming Water Cream
Match—56%55%54%
Price$112.36$17.50−$94.86$42.00−$70.36—
Shared key ingredients—6 of 144 of 144 of 14
Key difference—Peg/Ppg-18/18 DimethiconeOatmeal ExtractAcetyl Glucosamine
Irritancy Medium Medium Low Low
Drying alcohol————
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Product summary

"Mesoestetic - Dermamelan Intimate Home Depigmenting Gel Cream" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Mesoestetic - Dermamelan Intimate Home Depigmenting Gel Cream ticks this box. Glycerin, mannitol, sodium hyaluronate and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (cholesterol, helianthus annuus seed wax, jojoba esters, dimethicone and isostearyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We love that this moisturizer contains a good concentration of niacinamide 3.70% - 5.50%. Niacinamide is a perfect active in a moistruizer because it helps calm down inflamation in skin and support the skin barrier. More than that, it is helpful for most common skin concerns: it helps regulat oil production, help reduce acne and clogged pores, improve skin tone and prevent pigmentation marks. It also helps fight photodamage.
  • There is also Potassium Azeloyl Diglycinate (2.70% - 4.00%). In this formulation. It is a derivative of azelaic acid. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium Azeloyl Diglycinate is better soluble in water compared with Azelaic Acid. Because of this property, products with Potassium Azeloyl Digclycinate can have a nicer texture.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 84.99£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 28 studies and safety reviews.

  1. 1
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  2. 2
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  3. 3
    Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosaceancbi.nlm.nih.gov
  4. 4
    A Preliminary Clinical Evaluation of a Topical Product for Reducing Slight Rosacea Imperfectionsdovepress.com
  5. 5
    Azeloyl-Glycine: A new active in skin disequilibriumresearchgate.net
  6. 6
    Formulation and evaluation of the cream made from potassium azeloyl diglycinate as an anti-agingresearchgate.net
Mesoestetic Dermamelan Intimate Home Depigmenting Gel Cream
MesoesteticDermamelan Intimate Home Depigmenting Gel Cream
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