
“MD Advanced Hydration Crème”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, caprylyl glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide eop, ferric hexapeptide-35, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1
“Advance your skin’s health while you sleep with this time-released intensely hydrating (yet beautifully lightweight) crème, clinically proven to help correct visible signs of sun damage and aging.”
This product contains ferric hexapeptide-35, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
“A powerhouse “super moisturizer” packed with Hyaluronic Acid, Mushroom Peptide + Squalane to reduce wrinkles, decrease dark spots, tighten, brighten, smooth , and improve skin with each use.”
Effective ingredients missing or their concentration is too low


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One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinHelps attract water to the upper layer of the skin and improves the product texture
More about SorbitolA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
More about Cetyl alcoholA great emollient that can also have anti-oxidant properties
More about Vitis vinifera seed oilEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
More about C12-15 alkyl benzoateAn emollient that helps soften the skin. Could be comedogenic
More about Isopropyl myristateAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeHelps oil and water mix together
More about Sucrose polystearateHelps oil and water mix together
More about Glyceryl dilaurateIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide eopA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tetrapeptide-7A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-1A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Ferric hexapeptide-35Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
More about Tetrahexyldecyl ascorbateA mushroom extract that might help attract water to the upper layer of the skin
More about Tremella fuciformis extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating
More about Chamomilla recutita flower extractSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment
More about Laminaria digitata extractAn emollient that helps soften the skin and might help calm down inflammation
More about Carthamus tinctorius seed oilUsed as a fragrance. Can be irritating
More about Rosa damascena flower oilPlant extract that can be irritating and is a known allergen
More about Lavandula hybrida oilCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
More about Rosmarinus officinalis leaf extractA plant extract used as a fragrance. Can be irritating
More about Vanilla planifolia fruit extractHelps oil and water mix together
More about Sodium stearoyl glutamateHelps soften the upper layer of the skin and might as well help to attract moisture to its upper layer
More about Theobroma grandiflorum seed butterHelps preserve products and creates a nice product texture
More about Caprylyl glycolAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholHelps soften upper layer of the skin and can enhance penetration of other ingredients into the upper layer of the skin
More about Cetyl estersUsed to improve the product consistency and soften the upper layer of the skin
More about Hydrogenated polyisobuteneHelps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerUsed to create a thicker product consistency
More about Xanthan gumHelps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skin
More about PvpWater, Glycerin, Sorbitol, Caprylic/capric triglyceride, Cetyl alcohol, Vitis vinifera seed oil, C12-15 alkyl benzoate, Diisostearyl dimer dilinoleate, Isopropyl myristate, Squalane, Dimethicone, Sucrose polystearate, Glyceryl dilaurate, Niacinamide, Ceramide eop, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Ferric hexapeptide-35, Hydrolyzed ganoderma lucidum extract, Tetrahexyldecyl ascorbate, Tremella fuciformis extract, Chamomilla recutita flower extract, Laminaria digitata extract, Carthamus tinctorius seed oil, Lavandula angustifolia herb extract, Jasminum officinale flower extract, Cananga odorata flower oil, Santalum album oil, Rosa damascena flower oil, Salvia triloba leaf extract, Citrus aurantium dulcis flower oil, Lavandula hybrida oil, Rosmarinus officinalis leaf extract, Salvia officinalis oil, Vanilla planifolia fruit extract, Sodium stearoyl glutamate, Ppg-12/smdi copolymer, Theobroma grandiflorum seed butter, Caprylyl glycol, Glyceryl stearate, Cetearyl alcohol, Sorbitan laurate, Cetyl esters, Hydrogenated polyisobutene, Hydroxystearic acid, C18-36 acid glycol ester, C18-36 acid triglyceride, Carbomer, Xanthan gum, Pvp, Disodium edta, Sodium benzoate, Sodium hydroxide, Potassium sorbate
Retailers ranked by price — lowest first.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| MDSolarSciencesMD Advanced Hydration CrèmeYOUR PRODUCT | NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream | ROSE Ingleton MDSignature Moisturizer | DermaticaNourishing Ceramide + Peptides | |
|---|---|---|---|---|
| Match | — | 87% | 87% | 85% |
| Price | $76.00 | $60.00−$16.00 | $85.00+$9.00 | $21.47−$54.53 |
| Shared key ingredients | — | 7 of 14 | 7 of 14 | 7 of 14 |
| Key difference | — | Hexapeptide-11 | Ascorbyl Glucoside | Panthenol |
| Irritancy | High | Medium | Medium | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Kester Black Skin Drench MoisturiserMedicube PDRN Pink Peptide Cream
Judging from the ingredient list, "MDSolarSciences - MD Advanced Hydration Crème" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. MDSolarSciences - MD Advanced Hydration Crème ticks this box. Humectants in this product (glycerin, caprylyl glycol and sorbitol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide eop, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, carthamus tinctorius seed oil and isopropyl myristate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
The product retails for 76.00$ in the United States.
For a detailed price comparison: click here.
Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.
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