Medicube

Medicube PDRN Pink Peptide Cream

Name: Medicube - PDRN Pink Peptide Cream
Brand: Medicube

Efficacy100/100IrritancyMedium

See all ingredients

Edit

Works for

2 of 2 advertised claims delivered

Moisturizing

Ceramide ns, Acetyl hexapeptide-8 + 32 more

Strong evidence

What the product description says

“Salmon DNA PDRN pink moisturizing cream that hydrate deeply into the skin by improving skin barrier and boost skin elasticity while enhancing skin glow.”

Source: Medicube

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, cholesterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide ap, ceramide as, ceramide eop, ceramide np, ceramide ns, copper tripeptide-1, niacinamide, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol, phytosphingosine

Ceramide nsHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.55%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.6%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.25–0.5%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.25–0.45%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.35–0.65%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.1–3.8%

Ceramide apHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.5%

Ceramide asHeroEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%

Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.25%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.55%

Ethylhexyl olivateKey activeEffect: HighHelps soften the upper layer of the skin~0.7–1.05%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.65–0.95%

Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.25–0.5%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.5%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.15–0.3%

Limnanthes alba seed oilKey active· EmollientEffect: HighThis oil's cmposition is closest to rapeseed oil. It is a very stable oil and serves as an emoillient~0.3–0.55%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2%

Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.35–0.6%

PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.3–0.55%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.25–0.5%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.5%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.2–0.4%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.5%

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~2.4–2.9%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.3–0.6%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~1.4–1.8%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.9–4.8%

Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~1.3–1.6%

Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.45–0.65%

Evens skin tone

Niacinamide

Strong evidence

What the product description says

“Helps support uneven skin tone with Salmon PDRN and Hyaluronic acid : Salmon PDRN helps support uneven skin tone for clear complexion and Hyaluronic acid boost hydration for soothing and glowing”

Source: Medicube

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2%

Anti-blemish

Not advertised by the brand · Niacinamide, Phytosphingosine + 1 more

Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.3–0.55%

Centella asiatica leaf extractEffect: LowA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.~0.25–0.45%

Anti-aging

Not advertised by the brand · Adenosine, Niacinamide + 8 more

Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, centella asiatica leaf extract, copper tripeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.5%

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.25–0.45%

Centella asiatica leaf extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.~0.25–0.45%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Limnanthes alba seed oilEffect: LowThis oil's cmposition is closest to rapeseed oil. It is a very stable oil and serves as an emoillient~0.3–0.55%

Can it cause trouble?

Irritancy

2 strong irritants: Parfum, Rosa damascena extract

Medium risk

We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.25–0.5%est.

Rosa damascena extractOil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.High~0.25–0.5%est.

Hibiscus esculentus fruit extractA plant extract that might help to neutralize free radicals. It can be irritatingHigh~0.25–0.5%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.1–3.8%est.

1,2-hexanediolA preservativeMedium~0.8–1.15%est.

Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.5–0.75%est.

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.45–0.7%est.

Polyglyceryl-4 oleateHelps oil and water mix togetherMedium~0.5–0.75%est.

Disodium edtaStabilizes the product formulationMedium~0.45–0.65%est.

EthylhexylglycerinA preservativeMedium~0.3–0.6%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.3–0.55%est.

Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.25–0.5%est.

Centella asiatica leaf extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.Medium~0.25–0.45%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.2–0.4%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Fucus vesiculosus extract—3/5~0.25–0.5%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.6%est.

Edit

Alternatives

Cheaper, or higher on efficacy

TIRTIR Matcha Calming Cream 50ml

Cheaper86% match

$23.14

SUNGBOON EDITOR Alaska Salmon PDRN Ultra Moisturizing Barrier Cream

Cheaper83% match

$19.99

View all alternatives

User reviews

Would you recommend?

No community reviews yet.

Be the first — your take helps the next person decide.

Write a review · ~30s

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycereth-26~5.1–6.3%

Formula

Irritation risk: Low

Helps create a thicker product consistency

More about Glycereth-26

Butylene glycol~3.9–4.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Caprylic/capric triglyceride~3.1–3.8%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Cyclopentasiloxane~2.4–2.9%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

1,2-hexanediol~0.8–1.15%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Niacinamide~1.6–2%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Hydrogenated polydecene~1.4–1.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Isononyl isononanoate~1.3–1.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate

Cetearyl olivate~1–1.2%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Cetearyl olivate

Ethylhexyl olivate~0.7–1.05%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Ethylhexyl olivate

Glycerin~0.65–0.95%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Sorbitan olivate~0.55–0.8%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan olivate

Sodium acrylates copolymer~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.45–0.7%

Irritant · medium

Irritation risk: Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer

Polyglyceryl-4 oleate~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Polyglyceryl-4 oleate

Disodium edta~0.45–0.65%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Betaine~0.35–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Panthenol~0.35–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Ethylhexylglycerin~0.3–0.6%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Citric acid~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Parfum~0.25–0.5%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Adenosine~0.25–0.5%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Limnanthes alba seed oil~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-agingAnti-oxidation

This oil's cmposition is closest to rapeseed oil. It is a very stable oil and serves as an emoillient

More about Limnanthes alba seed oil

Sorbitan isostearate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Glyceryl acrylate/acrylic acid copolymer~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer

Rosa damascena extract~0.25–0.5%

Irritant · high

Irritation risk: High

Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.

More about Rosa damascena extract

Cyanocobalamin~0.25–0.5%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Sodium dna~0.25–0.5%

Formula

Irritation risk: Low

More about Sodium dna

Hydrogenated lecithin~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Cetearyl alcohol~0.3–0.6%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Stearic acid~0.45–0.65%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

Sodium hyaluronate~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hydroxypropyltrimonium hyaluronate~0.3–0.55%

Formula

Irritation risk: Low

More about Hydroxypropyltrimonium hyaluronate

Ceramide np~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Prunella vulgaris extract~0.3–0.5%

Formula

Irritation risk: Low

More about Prunella vulgaris extract

Fucus vesiculosus extract~0.25–0.5%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Fucus vesiculosus extract

Morinda citrifolia fruit extract~0.25–0.5%

Formula

Irritation risk: Low

More about Morinda citrifolia fruit extract

Momordica charantia fruit extract~0.25–0.5%

Formula

Irritation risk: Low

More about Momordica charantia fruit extract

Hibiscus esculentus fruit extract~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that might help to neutralize free radicals. It can be irritating

More about Hibiscus esculentus fruit extract

Ceramide ns~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

More about Ceramide ns

Sodium acetylated hyaluronate~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Hydrolyzed hyaluronic acid~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Centella asiatica leaf extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-inflammatoryReduces irritationReduces rednessAnti-agingAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.

More about Centella asiatica leaf extract

Cholesterol~0.3–0.6%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol

Phytosphingosine~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-blemish

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine

Ceramide as~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

More about Ceramide as

Ceramide ap~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

More about Ceramide ap

Hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Copper tripeptide-1~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Sodium hyaluronate crosspolymer~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Acetyl hexapeptide-8~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Palmitoyl pentapeptide-4~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4

Hydrolyzed sodium hyaluronate~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Palmitoyl tetrapeptide-7~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Palmitoyl tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Potassium hyaluronate~0.1–0.2%

Formula

Irritation risk: Low

More about Potassium hyaluronate

Ceramide eop~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces irritationMoisturizingAnti-inflammatory

More about Ceramide eop

Ingredient list view

Water, Glycereth-26, Butylene glycol, Caprylic/capric triglyceride, Cyclopentasiloxane, 1,2-hexanediol, Niacinamide, Hydrogenated polydecene, Isononyl isononanoate, Cetearyl olivate, Ethylhexyl olivate, Glycerin, Sorbitan olivate, Sodium acrylates copolymer, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Polyglyceryl-4 oleate, Disodium edta, Betaine, Panthenol, Ethylhexylglycerin, Citric acid, Parfum, Adenosine, Limnanthes alba seed oil, Sorbitan isostearate, Glyceryl acrylate/acrylic acid copolymer, Rosa damascena extract, Cyanocobalamin, Sodium dna, Hydrogenated lecithin, Cetearyl alcohol, Stearic acid, Sodium hyaluronate, Hydroxypropyltrimonium hyaluronate, Ceramide np, Prunella vulgaris extract, Fucus vesiculosus extract, Morinda citrifolia fruit extract, Momordica charantia fruit extract, Hibiscus esculentus fruit extract, Ceramide ns, Sodium acetylated hyaluronate, Hydrolyzed hyaluronic acid, Centella asiatica leaf extract, Cholesterol, Phytosphingosine, Ceramide as, Ceramide ap, Hyaluronic acid, Copper tripeptide-1, Sodium hyaluronate crosspolymer, Acetyl hexapeptide-8, Palmitoyl pentapeptide-4, Hydrolyzed sodium hyaluronate, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Potassium hyaluronate, Ceramide eop

Compare prices

Retailers ranked by price — lowest first.

Medicube

≈ $27.15

Buy

Amazon USPrice as of 10/23/2026 06:03 GMT

$48.52

Buy

Affiliate links · prices updated regularly · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MedicubePDRN Pink Peptide CreamYOUR PRODUCT	TIRTIRMatcha Calming Cream 50ml	NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream	SUNGBOON EDITORAlaska Salmon PDRN Ultra Moisturizing Barrier Cream
Match	—	86%	83%	83%
Price	$27.15	$23.14−$4.01	$60.00+$32.85	$19.99−$7.16
Shared key ingredients	—	18 of 30	19 of 30	18 of 30
Key difference	—	Dipeptide-2	Nonapeptide-1	3-O-Ethyl Ascorbic Acid
Irritancy	Medium	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

Cheaper alternatives? See how this stacks up against similar formulas.

We compare ingredient profiles across our catalog — pick the closest match for your budget.

Open dupe finder

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

1
Safety Assessment of Glycerin Ethoxylates as Used in Cosmeticscir-safety.org
2
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
3
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
4
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
5
Safety Assessment of Polyene Group as Used in Cosmeticscir-safety.org
6
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
7
Final Report on the Safety Assessment of Acrylates Copolymer and 33 Related Cosmetic Ingredientsjournals.sagepub.com
8
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
9
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
10
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
11
Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trialpubmed.ncbi.nlm.nih.gov
12
Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasisncbi.nlm.nih.gov
13
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
14
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
15
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
16
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
17
Polyphenol Composition and Antioxidant Potential of Hibiscus esculentus L. Fruit Cultivated in Nigerialiebertpub.com
18
Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory propertiesonlinelibrary.wiley.com
19
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
20
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
21
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
22
Centella asiatica in Dermatology: An Overviewonlinelibrary.wiley.com
23
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
24
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
25
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
26
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
27
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com

MedicubePDRN Pink Peptide Cream

Buy on Amazon$48.52 · as of 10/23 06:03 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$48.52 · as of 10/23 06:03 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.