Mario Badescu Advanced Peptide PDRN Jelly Cream

Mario Badescu Advanced Peptide PDRN Jelly Cream

Efficacy100/100IrritancyMedium
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Works for

3 of 3 advertised claims delivered

Anti-aging
Niacinamide, Palmitoyl tetrapeptide-7 + 2 more
Strong evidence
What the product description says
“targeting the look of fine lines”
Source: Mario Badescu

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tetrapeptide-7.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.6–3.9%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%
Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~2–3%
Palmitoyl tripeptide-1Under-dosedEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Moisturizing
Niacinamide, Palmitoyl tetrapeptide-7 + 9 more
Strong evidence
What the product description says
“lightweight, glycerin-rich jelly moisturizer that sinks in quickly to hydrate”
Source: Mario Badescu

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: palmitoyl tetrapeptide-7, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, palmitoyl tetrapeptide-7

Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.1–0.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.2–4.8%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.6–3.9%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.15%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.5%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.05–0.15%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.2–1.8%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.4–0.95%
Aloe barbadensis leaf juice· HumectantEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~2–3%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.7%
Palmitoyl tripeptide-1Under-dosedEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Evens skin tone
Niacinamide
Strong evidence
What the product description says
“evening the appearance of tone”
Source: Mario Badescu

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.6–3.9%
Anti-blemish
Not advertised by the brand · Niacinamide, Aloe barbadensis leaf juice
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.6–3.9%
Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~2–3%

Can it cause trouble?

Irritancy
1 strong irritant: Rosa canina bud extract
Medium risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.4–0.95%est.
Rosa canina bud extract—High~0.1–0.3%est.
Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.1–0.3%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~2–3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.7%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
1,2-hexanediolA preservativeMedium~0.1–0.5%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.15–0.55%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.1–0.5%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.1–0.45%est.
Cucumis sativus extract—Medium~0.05–0.3%est.
Potassium sorbateA preservativeMedium~0.05–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Fucus vesiculosus extract—3/5~0.05–0.3%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Propanediol~4.6–7%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Glycerin~3.2–4.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Niacinamide~2.6–3.9%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-blemishEvens skin toneAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Aloe barbadensis leaf juice~2–3%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialReduces irritationReduces rednessAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Maltodextrin~1.7–2.6%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Carbomer~1.4–2.1%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Butylene glycol~1.2–1.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Distarch phosphate~0.55–1.25%
Formula
Propylene glycol~0.4–0.95%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Sodium hydroxide~0.35–0.75%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Caprylyl glycol~0.2–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
1,2-hexanediol~0.1–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Sodium hyaluronate~0.15–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Sodium citrate~0.15–0.55%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Sodium lactate~0.1–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Citric acid~0.1–0.45%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Polysorbate 20~0.1–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Rosa canina bud extract~0.1–0.3%
Irritant · high
Chamomilla recutita flower extract~0.1–0.3%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract
Cucumis sativus extract~0.05–0.3%
Irritant · medium
Fucus vesiculosus extract~0.05–0.3%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Fucus vesiculosus extract
Potassium sorbate~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium benzoate~0.05–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Cyanocobalamin~0.05–0.15%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Palmitoyl tripeptide-1~0.05–0.2%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tetrapeptide-7~0.05–0.15%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Sodium dna~0.01–0.05%
Formula
Irritation risk
Low
More about Sodium dna
Ingredient list view

Water, Propanediol, Glycerin, Niacinamide, Aloe barbadensis leaf juice, Maltodextrin, Carbomer, Butylene glycol, Phenoxyethanol, Distarch phosphate, Propylene glycol, Sodium hydroxide, Caprylyl glycol, Chlorphenesin, 1,2-hexanediol, Sodium hyaluronate, Sodium citrate, Sodium lactate, Citric acid, Polysorbate 20, Rosa canina bud extract, Chamomilla recutita flower extract, Cucumis sativus extract, Fucus vesiculosus extract, Potassium sorbate, Sodium benzoate, Cyanocobalamin, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Sodium dna

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Amazon USPrice as of 10/25/2026 15:07 GMT
$13.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Mario BadescuAdvanced Peptide PDRN Jelly CreamYOUR PRODUCTSpectacle SkincarePerformance CrèmeMATTER OF FACTMaximalist Age-Defying MoisturizerKeys SoulcareFirm Belief Smoothing Peptide Cream
Match—94%91%91%
Price$13.99$101.60+$87.61$80.00+$66.01$20.67+$6.68
Shared key ingredients—6 of 76 of 76 of 7
Key difference—RetinalBakuchiolCopper Tripeptide-1
Irritancy Medium Medium Low Medium
Drying alcohol————
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Mario Badescu Advanced Peptide PDRN Jelly Cream
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Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.