Macrene Actives High Performance Neck and Decolletage Treatment
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Price as of 12/8/2022 1:3 GMT.
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Benefits
Promise: Anti-aging
What does the product description say?
Scientifically proven and dermatologist tested to reduce the appearance of fine lines and wrinkles, firm and tone the skin, reduce the appearance of blemishes and spots, smooth skin texture and soothe & hydrate the skin.
This product contains aspartic acid, resveratrol, serine, threonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
| Ingredient | Effectiveness | Concentration | Irritancy |
|---|---|---|---|
| aspartic acid | MEDIUM |  |  |
| resveratrol | MEDIUM | | |
| serine | MEDIUM | | |
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Promise: Evens skin tone
What does the product description say?
Scientifically proven and dermatologist tested to reduce the appearance of fine lines and wrinkles, firm and tone the skin, reduce the appearance of blemishes and spots, smooth skin texture and soothe & hydrate the skin.
This product contains ingredients (alanine, punica granatum extract, resveratrol) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.
| Ingredient | Effectiveness | Concentration | Irritancy |
|---|---|---|---|
| alanine | LOW | | |
| punica granatum extract | LOW | | |
| resveratrol | LOW | | |
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Promise: Moisturizing
What does the product description say?
Scientifically proven and dermatologist tested to reduce the appearance of fine lines and wrinkles, firm and tone the skin, reduce the appearance of blemishes and spots, smooth skin texture and soothe & hydrate the skin.
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
alanine, arginine.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, helianthus annuus seed oil.
| Ingredient | Effectiveness | Concentration | Irritancy |
|---|---|---|---|
| tremella fuciformis sporocarp extract | HIGH | | |
| arginine | HIGH | | |
| aspartic acid | HIGH | | |
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Other benefit: Anti-oxidation
This product contains antioxidants (resveratrol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - camellia sinensis leaf extract, ilex paraguariensis leaf extract, punica granatum extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
| Ingredient | Effectiveness | Concentration | Irritancy |
|---|---|---|---|
| resveratrol | HIGH | | |
| ilex paraguariensis leaf extract | MEDIUM | | |
| camellia sinensis leaf extract | MEDIUM | | |
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Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score:
66/100.
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US Retailers
Potential irritants
IRRITANCY
HIGH
| Ingredient | Irritancy | Skin Benefit |
|---|---|---|
| rosa damascena extract | |  |
| ilex paraguariensis leaf extract | | |
| alcohol | | |
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User reviews (0)
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Ingredients & concentrations
KEY INGREDIENTS
- alanine
- arginine
- aspartic acid
- bisabolol
- camellia sinensis leaf extract
- cholesterol
- citrulline
- glycerin
- glycine
- Sunflower seed oil
- histidine
- hydrolyzed sodium hyaluronate
- ilex paraguariensis leaf extract
- isoleucine
- kappaphycus alvarezii extract
- pca
- punica granatum extract
- resveratrol
- scenedesmus rubescens extract
- serine
- Jojoba oil
- sodium acetylated hyaluronate
- sodium hyaluronate
- sodium hyaluronate crosspolymer
- sodium lactate
- sodium pca
- theobroma cacao seed butter
- threonine
- Vitamin E
- tremella fuciformis sporocarp extract
- +26 more
| Ingredient | Estimated concentration |
|---|---|
| 45% - 55% | |
| Plain old water | |
| 4.3% - 5.2% | |
| Helps soften the upper layer of the skin | |
| 4.2% - 5.1% | |
| 3% - 3.7% | |
| One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant | |
| 2.4% - 2.9% | |
| A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function | |
| 2% - 2.4% | |
| Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air. | |
| 1.5% - 1.8% | |
| Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness | |
| 1.5% - 1.8% | |
| A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together | |
| 1.1% - 1.4% | |
| Helps water and oil mix together | |
| 0.9% - 1.1% | |
| One of the best moisturizing ingredients. Attracts water into the upper layer of the skin | |
| 0.65% - 1% | |
| Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation | |
| 0.5% - 0.75% | |
| A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective | |
| 0.45% - 0.7% | |
| Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation. | |
| 0.45% - 0.65% | |
| A plant extract that can help neutralize free radicals in skin. Can contain fragrand compounds like linalool that can be irritating | |
| 0.45% - 0.65% | |
| Might be helpful in neutralizing free radicals in skin | |
| 0.45% - 0.7% | |
| Helps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect | |
| 0.4% - 0.6% | |
| Mushroom extract that helps attract water to the upper layer of the skin | |
| 0.35% - 0.6% | |
| A plant extract that can contain an antioxidant compound | |
| 0.3% - 0.55% | |
| A red algae extract that can help attract water to the upper layer of the skin and might have some antioxidant properties | |
| 0.3% - 0.55% | |
| A micro-algae extract that might help attract water to the upper layer of the skin, support its barrier function, amd might help neutralize free radicals, but evidence of effectiveness in skin is lacking | |
| 0.3% - 0.55% | |
| Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone | |
| 0.25% - 0.45% | |
| An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties | |
| 0.25% - 0.5% | |
| Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself | |
| 0.25% - 0.5% | |
| Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging. | |
| 0.25% - 0.45% | |
| A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid | |
| 0.25% - 0.45% | |
| Attracts water into the upper layer of the skin | |
| 0.25% - 0.45% | |
| Attracts water into the upper layer of the skin | |
| 0.25% - 0.45% | |
| 0.25% - 0.45% | |
| An amino-acid that helps attract water to the upper layer of the skin | |
| 0.25% - 0.45% | |
| Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product | |
| 0.25% - 0.45% | |
| An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin | |
| 0.25% - 0.45% | |
| An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles | |
| 0.25% - 0.45% | |
| Naturally present in skin and helps to attract water to its upper layer | |
| 0.25% - 0.45% | |
| Helps to attract water to the upper layer of the skin and can help restore the skin barrier function | |
| 0.25% - 0.45% | |
| An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking | |
| 0.25% - 0.45% | |
| An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles | |
| 0.25% - 0.45% | |
| 0.25% - 0.5% | |
| 0.25% - 0.5% | |
| An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles | |
| 0.25% - 0.45% | |
| An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function | |
| 0.25% - 0.45% | |
| 0.25% - 0.45% | |
| 0.25% - 0.45% | |
| Naturally present in skin and helps to attract water to its upper layer | |
| 0.25% - 0.5% | |
| Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients. | |
| 0.3% - 0.55% | |
| An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products | |
| 0.25% - 0.45% | |
| Helps create a thicker product formulation | |
| 0.25% - 0.45% | |
| Used to stabilize product formulations | |
| 0.2% - 0.4% | |
| A preservative | |
| 0.55% - 0.85% | |
| 0.2% - 0.35% | |
| A preservative | |
| 0.15% - 0.3% | |
| A preservative | |
| 0.15% - 0.3% | |
| Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties | |
| TBC | |
| The ingredient is not recognized | |
| 0.2% - 0.35% | |
| An emollient that is naturally found in skin | |
| 0.1% - 0.2% | |
| A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients. | |
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Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation
- Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects
- Safety Assessment of Punica granatum -Derived Ingredients as Used in Cosmetics
- Topical formulation containing Ilex Paraguariensis extract increases metalloproteinases and myeloperoxidase activities in mice exposed to UVB radiation
- Chemical composition and antioxidant activity of yerba-mate (Ilex paraguariensis A.St.-Hil., Aquifoliaceae) extract as obtained by spray drying
- Essential oil and antioxidant activity of green mate and mate tea (Ilex paraguariensis) infusions
- Effect of green Coffea arabica L. seed oil on extracellular matrix components and water-channel expression in in vitro and ex vivo human skin models
- Cocoa polyphenols and their influence on parameters involved in ex vivo skin restructuring
- Carboxymethylation of polysaccharides from Tremella fuciformis for antioxidant and moisture-preserving activities
- Analyzing Lycopene Content in Fruits
- Psychoactive Properties of Microalgae
- Protection strategies to inhibit blue light irradiation effects in-vitro and in skin ex-vivo
- Skin permeation and antioxidant efficacy of topically applied resveratrol
- Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
- Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
- Resveratrol as a Multifunctional Topical Hypopigmenting Agent
- Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation
- Resveratrol: A Unique Antioxidant Offering a Multi-Mechanistic Approach for Treating Aging Skin
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies
- Dermatologic compositions comprising pyrrolidone-5-carboxylic acid and at least one entity chosen from citrulline, arginine and asparagine, and uses thereof in the treatment of atopic dermatitis
- Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proof
- In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmness
- Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency
- Functional glycine receptor in cultured human keratinocytes
- Combination of amino acids reduces pigmentation in B16F0 melanoma cells
- Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
- Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trial
- Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseases