Works for:
based on ingredients and %- Anti-aging
- Anti-oxidation
- Anti-blemish
- Moisturizing
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"IOPE - Stem III Ampoule" is effective for: Anti-aging, Anti-blemish, Moisturizing and Evens skin tone
Ingredient callouts
- A good concentration of Niacinamide (1.60% - 2.50%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Peptides (acetyl tetrapeptide-11 0.01% - 0.10%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.10% - 0.40%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiatic acid 0.10% - 0.30%, madecassic acid 0.10% - 0.30% and asiaticoside 0.10% - 0.30% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
- Humectants (mannitol 0.15% - 0.50%, betaine 1.20% - 1.80% and glycerin 4.50% - 6.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 145.00A$ in Australia and from 63.10$ up to 88.99$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
Fight signs of aging and brighten complexion with this hypoallergenic ampoule, formulated free of artificial colorants, fragrances and mineral oils.
Source: Yesstyle
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-11, asiaticoside.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Anti-oxidation
This product contains antioxidants (asiaticoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
A plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
betaine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cholesterol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-11, niacinamide
Helps to attract water to the upper layer of the skin
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin and improves the product texture
An emollient that is naturally found in skin
A plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps attract water to the upper layer of the skin and soften it
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin
Helps attract water to the upper layer of the skin and improves the product texture
Used to create a nice product texture
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Glycerin, Butylene glycol, Alcohol, Sorbitol, Niacinamide, 1,2-hexanediol, Betaine, Methyl gluceth-20, Caprylic/capric triglyceride, Dimethicone, Propanediol, Ammonium acryloyldimethyltaurate/vp copolymer, Hydrogenated lecithin, Glyceryl polymethacrylate, Allantoin, Xanthan gum, Cholesterol, Mannitol, Ethylhexylglycerin, Adenosine, Asiaticoside, Madecassic acid, Asiatic acid, Beta-glucan, Dextrin, Theobroma cacao extract, Crithmum maritimum callus culture filtrate, Sodium methyl stearoyl taurate, Morinda citrifolia extract, Acetyl tetrapeptide-11, Tocopherol
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Profile of wound healing process induced by allantoin
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Centella asiatica in cosmetology
- Contact dermatitis due to Madecassol
- Centella asiatica in Dermatology: An Overview
- Contact dermatitis due to Madecassol
- Centella asiatica in Dermatology: An Overview
- β-Glucans: Multi-Functional Modulator of Wound Healing
- Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucan
- Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Review
- Anticancer properties of low molecular weight oat beta-glucan – An in vitro study
- A critical review on production and industrial applications 2 of beta-glucans
- Improving skin function with CM-glucan, a biological response modifier from yeast
- Preparation, characterization, and biological properties of β-glucans
- Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatus
- Vitamin E in dermatology
- Vitamin E and Skin Health