GLOWBIOTICS ULTIMATE YOUTH RESTORING SERUM

GLOWBIOTICS ULTIMATE YOUTH RESTORING SERUM

Efficacy100/100IrritancyMedium

Works for

Anti-aging
Retinol, Myristoyl nonapeptide-3 + 2 more
Works well
What the product description says
“This advanced formula combines powerful retinoids and biomimetic peptides to reduce fine lines and wrinkles, boost collagen and elastin production, and enhance skin repair.”
Source: GLOWBIOTICS

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: myristoyl nonapeptide-3.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Myristoyl nonapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.65%
Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.4–2.1%
Magnesium ascorbyl phosphateEffect: Low, below effective doseA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~0.35–0.85%
Evens skin tone
Retinol, Dimethylmethoxy chromanyl palmitate + 2 more
Works well
What the product description says
“Enjoy a brighter, even complexion as unwanted pigmentation fades, and benefit from instant lifting and tightening effects.”
Source: GLOWBIOTICS

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: dimethylmethoxy chromanyl palmitate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Dimethylmethoxy chromanyl palmitateKey activeEffect: MediumAn oil-soluble compound that has been shown in laboratory studies (in a petri dish, not on human volunteers) to inhibit melanin production in skin and help even out the skin tone. More research is needed to understand if it works in real life~0.3–0.75%
Magnesium ascorbyl phosphateEffect: Low, below effective doseA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~0.35–0.85%
Pisum sativum extractEffect: Low, below effective doseMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking~0.1–0.45%
Moisturizing
Side benefit the brand mentions · Urea, Myristoyl nonapeptide-3 + 7 more
Works well
What the product description says
“Fights against all signs of aging including dehydration, age spots, ineffective barrier function, ptosis. wrinkles.”
Source: N/A

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, hydrolyzed wheat protein.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: myristoyl nonapeptide-3, urea

UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~1.6–2.4%
Myristoyl nonapeptide-3HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.65%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–6.1%
Hydrolyzed wheat proteinKey active· HumectantEffect: MediumCan help attract water to the upper layer of the skin. Avoid if sensitive to gluten~0.05–0.3%
Aloe barbadensis leaf juice· HumectantEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.4–2.1%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.3–1.9%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.15–0.65%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.05–0.25%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.35–0.8%
Exfoliation
Side benefit · Retinol, Urea
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
UreaKey activeEffect: MediumNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~1.6–2.4%
Anti-blemish
Side benefit the brand mentions · Retinol, Aloe barbadensis leaf juice
Works well
What the product description says
“pores and redness caused by vascular congestion. *Renovage™ is a trademark of Sederma.”
Source: N/A

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.4–2.1%
Anti-oxidation
Side benefit · Retinol, Zingiber officinale root extract + 2 more
Works well

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~2.7–4%
Zingiber officinale root extractEffect: LowA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking~0.3–0.75%
Magnesium ascorbyl phosphateEffect: Low, below effective doseA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~0.35–0.85%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.3–0.75%

Can it cause trouble?

Irritancy
2 strong irritants: Retinol, Zingiber officinale root extract
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~2.7–4%est.
Zingiber officinale root extractA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lackingHigh~0.3–0.75%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~1.4–2.1%est.
Isoceteth-20Helps water and oil mix togetherMedium~0.5–1.2%est.
Magnesium ascorbyl phosphateA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very highMedium~0.35–0.85%est.
Dimethylmethoxy chromanyl palmitateAn oil-soluble compound that has been shown in laboratory studies (in a petri dish, not on human volunteers) to inhibit melanin production in skin and help even out the skin tone. More research is needed to understand if it works in real lifeMedium~0.3–0.75%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.35–0.8%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.15–0.65%est.
Sucrose dilaurateHelps oil and water mix together. Can be used as a cleansing agentMedium~0.15–0.65%est.
Sodium cocoyl glutamateHelps oil and water mix togetherMedium~0.2–0.7%est.
Pisum sativum extractMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lackingMedium~0.1–0.45%est.
Hydrolyzed wheat proteinCan help attract water to the upper layer of the skin. Avoid if sensitive to glutenMedium~0.05–0.3%est.
1,2-hexanediolA preservativeMedium~0.05–0.25%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.05–0.25%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Macrocystis pyrifera extract—3/5~0.1–0.35%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4–6.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydroxyethylcellulose~3.7–5.6%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Retinol~2.7–4%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
MattifyingExfoliationAnti-oxidationAnti-agingEvens skin toneAnti-blemish

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Glyceryl diretinoate~2–3.1%
Formula
Urea~1.6–2.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Aloe barbadensis leaf juice~1.4–2.1%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialAnti-inflammatoryReduces rednessReduces irritationAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Butylene glycol~1.3–1.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Hydroxyphenyl propamidobenzoic acid~1–1.5%
Formula
Irritation risk
Low
Works for
Anti-inflammatory

Might help to reduce inflammation in skin, but solid research is lacking

More about Hydroxyphenyl propamidobenzoic acid
Acetyl carboxymethyl cocoyl glycine~0.8–1.25%
Formula
Rice/saccharomyces lyce/lactobacillis ferment lysate…
Not recognized
Isoceteth-20~0.5–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Isoceteth-20
Peg-40 stearate~0.45–1%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Peg-40 stearate
Magnesium ascorbyl phosphate~0.35–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-agingAnti-oxidation

A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high

More about Magnesium ascorbyl phosphate
Bisabolol~0.3–0.75%
Formula
Irritation risk
Low
Works for
Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Zingiber officinale root extract~0.3–0.75%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking

More about Zingiber officinale root extract
Dimethylmethoxy chromanyl palmitate~0.3–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin tone

An oil-soluble compound that has been shown in laboratory studies (in a petri dish, not on human volunteers) to inhibit melanin production in skin and help even out the skin tone. More research is needed to understand if it works in real life

More about Dimethylmethoxy chromanyl palmitate
Caprylic/capric triglyceride~0.35–0.8%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Teprenone~0.2–0.75%
Formula
Irritation risk
Low
More about Teprenone
Myristoyl octapeptide-1~0.15–0.7%
Formula
Myristoyl octapeptide-2
Not recognized
Myristoyl nonapeptide-3~0.15–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Myristoyl nonapeptide-3
Safflower acid~0.2–0.75%
Formula
Irritation risk
Low
Works for
Cleansing
More about Safflower acid
Pentylene glycol~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Maltodextrin~0.15–0.55%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Sucrose dilaurate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Sucrose dilaurate
Sodium cocoyl glutamate~0.2–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium cocoyl glutamate
Pisum sativum extract~0.1–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking

More about Pisum sativum extract
Macrocystis pyrifera extract~0.1–0.35%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Macrocystis pyrifera extract
Hydrolyzed wheat protein~0.05–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten

More about Hydrolyzed wheat protein
1,2-hexanediol~0.05–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl glycol~0.05–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Tropolone~0.05–0.15%
Formula
Irritation risk
Low
More about Tropolone
Ingredient list view

Water, Glycerin, Hydroxyethylcellulose, Retinol, Glyceryl diretinoate, Urea, Aloe barbadensis leaf juice, Butylene glycol, Hydroxyphenyl propamidobenzoic acid, Acetyl carboxymethyl cocoyl glycine, Unknown, Isoceteth-20, Peg-40 stearate, Magnesium ascorbyl phosphate, Bisabolol, Zingiber officinale root extract, Dimethylmethoxy chromanyl palmitate, Caprylic/capric triglyceride, Teprenone, Myristoyl octapeptide-1, Unknown, Myristoyl nonapeptide-3, Safflower acid, Pentylene glycol, Maltodextrin, Sucrose dilaurate, Sodium cocoyl glutamate, Pisum sativum extract, Macrocystis pyrifera extract, Hydrolyzed wheat protein, 1,2-hexanediol, Caprylyl glycol, Tropolone

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
GLOWBIOTICSULTIMATE YOUTH RESTORING SERUMYOUR PRODUCTGlowbiotics MDUltimate Youth Restoring SerumDr Dennis GrossHyaluronic Marine Hydration Booster DeluxePCA SKINIntensive Age Refining Treatment 0.5 Percent Pure Retinol Night
Match—87%77%77%
Price———$120.00
Shared key ingredients—7 of 75 of 73 of 7
Key difference—Octapeptide-2Lactic AcidNiacinamide
Irritancy Medium High Medium Medium
Drying alcohol————
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Product summary

"GLOWBIOTICS - ULTIMATE YOUTH RESTORING SERUM" is effective for: Evens skin tone, Moisturizing, Anti-aging, Anti-blemish and Exfoliation

Ingredient callouts

  • this product contains an effective form of Retinoids (vitamin A): retinol 2.00% - 3.00%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
  • Peptides (myristoyl nonapeptide-3 1.00% - 1.50% and octapeptide-2 1.20% - 1.80%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • Humectants (urea 0.50% - 1.15% and glycerin 4.00% - 6.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 230.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
  6. 6
GLOWBIOTICS ULTIMATE YOUTH RESTORING SERUM
GLOWBIOTICSULTIMATE YOUTH RESTORING SERUM

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As an Amazon Associate, WIMJ earns from qualifying purchases.