Eve Rebirth Bio-Intelligent Wrinkle Filler Cream

Eve Rebirth Bio-Intelligent Wrinkle Filler Cream

Efficacy66/100IrritancyHigh
Edit

Works for

2 of 3 advertised claims delivered

Moisturizing
Copper heptapeptide-14 pantothenate, Heptapeptide-15 palmitate + 19 more
Strong evidence
What the product description says
“Transform your skin with Eve Rebirth Bio-Intelligent Wrinkle Filler Cream , a revolutionary, anti-ageing moisturiser that utilises Biointelligent Microingredients to target the source of ageing under the skin.”
Source: Mankind

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: dextran, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: copper heptapeptide-14 pantothenate, heptapeptide-15 palmitate

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.6–0.9%
PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~0.75–1.15%
Copper heptapeptide-14 pantothenateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.2–1.5%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.25–0.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.4–2.9%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.55%
Heptapeptide-15 palmitateHero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.4–0.65%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1–1.2%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~1.4–1.8%
TrihydroxystearinKey activeEffect: MediumHelps soften the upper layer of the skin and improve the product texture~0.25–0.5%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.35–0.65%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~3.1–3.8%
Coco-caprylateKey active· EmollientEffect: MediumAn emollient that softens skin and creates a nice product texture~1.9–2.4%
Dicaprylyl carbonate· EmollientEffect: LowHelps products spread more easily and works as an emollient to soften skin~1.6–2%
Polyglyceryl-6 distearateEffect: LowHelps oil and water mix together while softening the upper layer of the skin~3.4–4.2%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.15–0.25%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.3–0.55%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.7%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%
Anti-aging
Heptapeptide-15 palmitate, Copper heptapeptide-14 pantothenate + 2 more
Strong evidence
What the product description says
“Helping to combat fine lines, wrinkles and age spots, the cream contains dehydrated and cross-linked Hyaluronic Acid microspheres that perform a filling and plumping effect to smoothen the appearance of wrinkles, whilst a combination of Vitamin C and E protect against free radicals and brighten the complexion.”
Source: Mankind

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains heptapeptide-15 palmitate.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: copper heptapeptide-14 pantothenate.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Heptapeptide-15 palmitateKey activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Copper heptapeptide-14 pantothenateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%
Sodium ascorbyl phosphateEffect: Low, below effective doseA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.5–0.7%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.7%
Evens skin tone
No ingredient credited for this claim
No evidence
What the product description says
“Helping to combat fine lines, wrinkles and age spots, the cream contains dehydrated and cross-linked Hyaluronic Acid microspheres that perform a filling and plumping effect to smoothen the appearance of wrinkles, whilst a combination of Vitamin C and E protect against free radicals and brighten the complexion.”
Source: Mankind

Effective ingredients missing or their concentration is too low

Can it cause trouble?

Irritancy
3 strong irritants: Achillea millefolium extract, Calendula officinalis flower extract + 1 more — patch-test recommended
High risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Achillea millefolium extractPlant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritatingHigh~0.55–0.85%est.
Calendula officinalis flower extractA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritatingHigh~0.45–0.65%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.25%est.
Polyglyceryl-6 distearateHelps oil and water mix together while softening the upper layer of the skinMedium~3.4–4.2%est.
Coco-caprylateAn emollient that softens skin and creates a nice product textureMedium~1.9–2.4%est.
Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.5–0.7%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.4–0.65%est.
Sorbitan palmitateHelps water and oil mix together and stabilize the product formulationMedium~0.3–0.6%est.
Polyglyceryl-3 beeswaxHelps water and oil mix together. Could be an allergen (beeswax)Medium~0.3–0.6%est.
Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.35–0.65%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.4%est.
Polyvinyl alcoholHelps improve the product textureMedium~0.15–0.3%est.
EthylhexylglycerinA preservativeMedium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~1.4–1.8%est.
Edit

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Write a review · ~30s

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Propanediol~4.4–5.3%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Polyglyceryl-6 distearate~3.4–4.2%
Irritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Polyglyceryl-6 distearate
Cetyl palmitate~3.1–3.8%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Glycerin~2.4–2.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Coco-caprylate~1.9–2.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that softens skin and creates a nice product texture

More about Coco-caprylate
Dicaprylyl carbonate~1.6–2%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps products spread more easily and works as an emollient to soften skin

More about Dicaprylyl carbonate
Ethylhexyl palmitate~1.4–1.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Dimethicone~1.2–1.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Cyclopentasiloxane~1–1.2%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Polymethylsilsesquioxane~0.75–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane
Sodium hyaluronate~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Echinacea pallida extract~0.5–0.75%
Formula
Achillea millefolium extract~0.55–0.85%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritating

More about Achillea millefolium extract
Calendula officinalis flower extract~0.45–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Sodium ascorbyl phosphate~0.5–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate
Tocopherol~0.45–0.7%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Copper heptapeptide-14 pantothenate~0.4–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Copper heptapeptide-14 pantothenate
Heptapeptide-15 palmitate~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Heptapeptide-15 palmitate
Jojoba esters~0.4–0.65%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Sorbitan olivate~0.35–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Sorbitan palmitate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together and stabilize the product formulation

More about Sorbitan palmitate
Cetyl alcohol~0.35–0.65%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Polyglyceryl-3 beeswax~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together. Could be an allergen (beeswax)

More about Polyglyceryl-3 beeswax
Xanthan gum~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium stearoyl glutamate~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate
Sorbitol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Trihydroxystearin~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and improve the product texture

More about Trihydroxystearin
Glucomannan~0.25–0.5%
Formula
Irritation risk
Low
More about Glucomannan
Dextran~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Helianthus annuus seed oil~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Tetrasodium glutamate diacetate~0.25–0.45%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Citric acid~0.25–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium polyacrylate~0.25–0.5%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Lecithin~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Parfum~0.15–0.25%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Lactic acid/glycolic acid copolymer~0.15–0.25%
Formula
Polyvinyl alcohol~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Helps improve the product texture

More about Polyvinyl alcohol
Polysilicone-11~0.15–0.25%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Hdi/trimethylol hexyllactone crosspolymer~0.1–0.2%
Formula
Irritation risk
Low

Used to create a silky product texture and add volume to products

More about Hdi/trimethylol hexyllactone crosspolymer
Phenoxyethanol~0.1–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Propanediol, Polyglyceryl-6 distearate, Cetyl palmitate, Glycerin, Coco-caprylate, Dicaprylyl carbonate, Ethylhexyl palmitate, Dimethicone, Cyclopentasiloxane, Polymethylsilsesquioxane, Sodium hyaluronate, Echinacea pallida extract, Achillea millefolium extract, Calendula officinalis flower extract, Sodium ascorbyl phosphate, Tocopherol, Copper heptapeptide-14 pantothenate, Heptapeptide-15 palmitate, Jojoba esters, Sorbitan olivate, Sorbitan palmitate, Cetyl alcohol, Polyglyceryl-3 beeswax, Xanthan gum, Sodium stearoyl glutamate, Sorbitol, Trihydroxystearin, Glucomannan, Dextran, Helianthus annuus seed oil, Tetrasodium glutamate diacetate, Citric acid, Sodium polyacrylate, Lecithin, Parfum, Lactic acid/glycolic acid copolymer, Polyvinyl alcohol, Polysilicone-11, Hdi/trimethylol hexyllactone crosspolymer, Phenoxyethanol, Ethylhexylglycerin

Compare prices

Retailers ranked by price — lowest first.

Mankind
≈ $161.58
Buy

Affiliate links · prices updated regularly

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Eve RebirthBio-Intelligent Wrinkle Filler CreamYOUR PRODUCTAdam RevolutionBio-Intelligent Anti-ageing MoisturiserLumeneNordic Ageless [AJATON] Radiant Youth Night CreamLIFTLABLIFT + PERFECT Total Rejuvenation Cream
Match—73%64%56%
Price$161.67$161.67$57.49−$104.18$143.04−$18.63
Shared key ingredients—13 of 136 of 138 of 13
Key difference——NiacinamideAcetyl Tetrapeptide-11
Irritancy High High Medium High
Drying alcohol——— Contains drying alcohol
View product Shop Shop Shop
Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Product summary

"Eve Rebirth - Bio-Intelligent Wrinkle Filler Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Heptapeptide-15 palmitate, dextran, glycerin, sodium hyaluronate and sorbitol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Jojoba esters, dimethicone, helianthus annuus seed oil, cetyl alcohol and cetyl palmitate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (heptapeptide-15 palmitate 0.35% - 0.65% and copper heptapeptide-14 pantothenate 0.40% - 0.65%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 11.25$ up to 161.00$ in the United States, for 105.80CA$ in Canada and from 60.44£ up to 120.87£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 24 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
Eve Rebirth Bio-Intelligent Wrinkle Filler Cream
Eve RebirthBio-Intelligent Wrinkle Filler Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.