E45 itch relief cream

E45 itch relief cream

Efficacy100/100IrritancyLow

Works for

Moisturizing
Paraffinum liquidum, Urea + 6 more
Works well
What the product description says
“E45 itch relief cream is a non-greasy formula specially designed to soothe and hydrate skin affected by eczema, dermatitis, pruritus and more.”
Source: Lloyds Pharmacy

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetyl palmitate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum, urea

Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~5.3–7.9%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations5%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~22–33%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~4.2–6.3%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.3–2%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~3.2–4.8%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~2.6–3.9%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~2.1–3.1%

Can it cause trouble?

Irritancy
1 flagged ingredient
Low risk
We flag 1 ingredient with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.5–1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Laureth-93%
Formula
Irritation risk
Low
Works for
Cleansing
More about Laureth-9
Urea5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Dimethicone~22–33%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Phenyl dimethicone~8.9–13.4%
Formula
Paraffinum liquidum~5.3–7.9%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Cetyl palmitate~4.2–6.3%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Stearic acid~3.2–4.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Palmitic acid~2.6–3.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Octyldodecanol~2.1–3.1%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Glycerin~1.3–2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Polysorbate
Not recognized
Carbomer~1–1.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Tromethamine~0.85–1.25%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Benzyl alcohol~0.5–1%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Water~0.3–0.75%
Formula
Irritation risk
Low

Plain old water

More about Water
Ingredient list view

Laureth-9, Urea, Dimethicone, Phenyl dimethicone, Paraffinum liquidum, Cetyl palmitate, Stearic acid, Palmitic acid, Octyldodecanol, Glycerin, Unknown, Carbomer, Tromethamine, Benzyl alcohol, Water

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🇬🇧 Amazon UK (UK)Price as of 11/8 06:33 GMT
≈ $10.05
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🇨🇦 Amazon CA (CA)
Price unavailable Out of stock
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🇦🇺 Amazon Australia (AU)50 Grams
Price unavailable Out of stock
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
E45itch relief creamYOUR PRODUCTSVRXERIAL 30 Body CreamNeutrogenaNorwegian Formula Intense Repair Foot Cream CallusesMixaUrea Cica Repair
Match—59%55%55%
Price—$23.42$34.47$6.71
Shared key ingredients—3 of 44 of 44 of 4
Key difference—Salicylic AcidGlycineNiacinamide
Irritancy Low Low Low Medium
Drying alcohol——— Contains drying alcohol
View product Shop Shop Shop

More alternatives: Shiseido Urea 10% Body CreamAvène Akérat Body Cream

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Product summary

Judging from the ingredient list, "E45 - itch relief cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (urea and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Dimethicone, cetyl palmitate, octyldodecanol, palmitic acid and paraffin in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 2.99£ up to 7.00£ in the United Kingdom and for 28.16$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.

  1. 1
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
E45 itch relief cream
E45itch relief cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.