Dr Dennis Gross

Dr Dennis Gross DRx Blemish Solutions Breakout Clearing Gel

Name: Dr Dennis Gross - DRx Blemish Solutions Breakout Clearing Gel
Brand: Dr Dennis Gross

Efficacy95/100IrritancyHigh

See all ingredients

Works for

Exfoliation

Salicylic acid, Glycolic acid + 1 more

Works well

What the product description says

“Saturated with 2% Salicylic Acid, the gel exfoliates the complexion, buffing away dead skin cells and unclogging pores.”

Source: Mankind

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid, retinol, salicylic acid.

Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~1.9–2.3%

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.3–0.6%

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%

Evens skin tone

Retinol, Glutathione + 6 more

Works well

What the product description says

“What’s more, the ingredient blurs the appearance of acne marks and uplifts pimple-causing bacteria, clarifying the complexion.”

Source: Mankind

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains glutathione, glycolic acid, salicylic acid. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: ferulic acid.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.45–0.7%

Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.3–0.55%

Salicylic acidEffect: LowUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~1.9–2.3%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.45%

NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.35–0.65%

Potassium azeloyl diglycinateUnder-dosedA derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture~0.25–0.45%

Anti-aging

Retinol, Glycolic acid + 5 more

Works well

What the product description says

“Finally, Monk’s Pepper hydrates and nourishes the visage, revealing a younger-looking and healthier-feeling surface.”

Source: Mankind

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, glycolic acid.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: ferulic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.2–0.35%

Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.25–0.45%

Anti-blemish

Salicylic acid, Retinol + 7 more

Works well

What the product description says

“Fast-acting, this gel combats both the cause and appearance of imperfections and blemishes.”

Source: Mankind

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol, salicylic acid. These ingredients is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycolic acid, zinc pca

Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~1.9–2.3%

Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.3–0.6%

Zinc pcaKey activeEffect: MediumA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.2–0.35%

Carnitine hclEffect: LowMight be helpful in decreasing sebum production making the skin less oily. Is claimed to be able to support ceramide production in skin that leads to better hydration, but evidence is lacking. Is able to attract water to the upper layer of the skin~0.65–1%

Moisturizing

Glycerin, Carnitine hcl + 10 more

Works

What the product description says

“Finally, Monk’s Pepper hydrates and nourishes the visage, revealing a younger-looking and healthier-feeling surface.”

Source: Mankind

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, saccharide isomerate.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.6–1.9%

Carnitine hclKey active· HumectantEffect: MediumMight be helpful in decreasing sebum production making the skin less oily. Is claimed to be able to support ceramide production in skin that leads to better hydration, but evidence is lacking. Is able to attract water to the upper layer of the skin~0.65–1%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.4%

Saccharide isomerateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.25–0.4%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.25–0.45%

Zinc pcaKey active· HumectantEffect: HighA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.2–0.35%

Potassium gluconateEffect: LowA mineral that might be able to support skin hydration, but convincing research on its effectiveness in topical skincare is lacking~0.25–0.4%

Anti-oxidation

Side benefit · Glutathione, Ferulic acid + 6 more

Works well

This product contains antioxidants (ferulic acid, glutathione, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Ferulic acidKey activeEffect: HighA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.3–0.55%

Vitex agnus-castus extractEffect: LowA plant extract that might have some antioxidant properties but evidence of effectiveness in skin is missing~0.55–0.8%

BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.3–0.6%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.45%

Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.45%

Can it cause trouble?

Irritancy

4 strong irritants: Alcohol denat., Hamamelis virginiana water + 2 more — patch-test recommended

High risk

We flagged 23 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~7.2–8.8%est.

Hamamelis virginiana waterA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~4.1–5%est.

Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~1.9–2.3%est.

Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.3–0.6%est.

RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.25–0.45%est.

Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.25–0.45%est.

FarnesolAdded to create a nice product smell. Can be irritatingHigh~0.2–0.4%est.

Potassium hydroxideUsed to adjust the pH level of productsMedium~1–1.2%est.

Vitex agnus-castus extractA plant extract that might have some antioxidant properties but evidence of effectiveness in skin is missingMedium~0.55–0.8%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.45–0.7%est.

Phytic acidAn alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmeticsMedium~0.3–0.6%est.

Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.3–0.5%est.

Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.25–0.45%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.45%est.

EthoxydiglycolHelps to improve the product consistencyMedium~0.2–0.4%est.

Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.4%est.

BhtA preservativeMedium~0.2–0.4%est.

BhaHelps preserve the product formulationMedium~0.2–0.4%est.

Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.2–0.4%est.

T-butyl alcoholUsed to dissolve other ingredients and to improve smell of products. It could be irritatingMedium~0.15–0.3%est.

Benzoic acidA preservativeMedium~0.15–0.3%est.

Potassium sorbateA preservativeMedium~0.1–0.25%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

Cheaper, or higher on efficacy

Glytone Enhance Brightening Solution

CheaperHigher efficacy · 100/10068% match

$30.64

Medik8 Blemish SOS Treatment

CheaperHigher efficacy · 100/10065% match

$28.17

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Alcohol denat.~7.2–8.8%

Irritant · high

Irritation risk: High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.

Hamamelis virginiana water~4.1–5%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana water

Pvm/ma decadiene crosspolymer~3.1–3.8%

Formula

Irritation risk: Low

More about Pvm/ma decadiene crosspolymer

Salicylic acid~1.9–2.3%

Hero · Anti-blemishIrritant · high

Irritation risk: High

Works for

Anti-inflammatoryAnti-blemishExfoliationAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid

Dimethyl isosorbide~1.8–2.2%

Formula

Irritation risk: Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide

Glycerin~1.6–1.9%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Polysorbate 20~1.3–1.6%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Potassium hydroxide~1–1.2%

Irritant · medium

Irritation risk: Medium

Used to adjust the pH level of products

More about Potassium hydroxide

Carnitine hcl~0.65–1%

Key active

Irritation risk: Low

Works for

MattifyingMoisturizingAnti-blemish

Might be helpful in decreasing sebum production making the skin less oily. Is claimed to be able to support ceramide production in skin that leads to better hydration, but evidence is lacking. Is able to attract water to the upper layer of the skin

More about Carnitine hcl

Vitex agnus-castus extract~0.55–0.8%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some antioxidant properties but evidence of effectiveness in skin is missing

More about Vitex agnus-castus extract

Glutathione~0.45–0.7%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Bisabolol~0.3–0.6%

Formula

Irritation risk: Low

Works for

Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol

Niacinamide~0.35–0.65%

Under-dosed

Irritation risk: Low

Works for

Anti-blemishEvens skin toneAnti-agingMoisturizingReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Phytic acid~0.3–0.6%

Irritant · medium

Irritation risk: Medium

An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics

More about Phytic acid

Glycolic acid~0.3–0.6%

Key activeIrritant · high

Irritation risk: High

Works for

ExfoliationEvens skin toneAnti-agingAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid

Ferulic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-oxidationEvens skin toneAnti-inflammatoryAnti-aging

A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%

More about Ferulic acid

Leuconostoc/radish root ferment filtrate~0.3–0.5%

Irritant · medium

Irritation risk: Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate

Retinol~0.25–0.45%

Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high

Irritation risk: High

Works for

Anti-agingAnti-oxidationExfoliationMattifyingAnti-blemishEvens skin tone

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol

Chamomilla recutita flower extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract

Aloe barbadensis leaf juice~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingReduces rednessReduces irritationAntibacterialAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice

Farnesol~0.2–0.4%

Irritant · high

Irritation risk: High

Added to create a nice product smell. Can be irritating

More about Farnesol

Sodium pantothenate~0.25–0.45%

Formula

Irritation risk: Low

More about Sodium pantothenate

Potassium azeloyl diglycinate~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

Anti-blemishEvens skin toneAnti-inflammatoryMoisturizing

A derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture

More about Potassium azeloyl diglycinate

Camellia sinensis leaf extract~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Phospholipids~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Tocopheryl acetate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Saccharide isomerate~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Saccharide isomerate

Sodium hyaluronate~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Soy isoflavones~0.2–0.4%

Formula

Irritation risk: Low

More about Soy isoflavones

Zinc pca~0.2–0.35%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-blemishAnti-oxidationAnti-aging

A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing

More about Zinc pca

Ethoxydiglycol~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps to improve the product consistency

More about Ethoxydiglycol

Octoxynol-9~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

More about Octoxynol-9

Disodium edta~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Potassium gluconate~0.25–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

A mineral that might be able to support skin hydration, but convincing research on its effectiveness in topical skincare is lacking

More about Potassium gluconate

Citric acid~0.25–0.4%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Pentasodium pentetate~0.25–0.45%

Formula

Irritation risk: Low

Helps preserve the product formulation

More about Pentasodium pentetate

Bht~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Bht

Bha~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps preserve the product formulation

More about Bha

Sodium citrate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate

T-butyl alcohol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Used to dissolve other ingredients and to improve smell of products. It could be irritating

More about T-butyl alcohol

Sodium glycolate~0.15–0.3%

Formula

Irritation risk: Low

More about Sodium glycolate

Denatonium benzoate~0.15–0.25%

Formula

Irritation risk: Low

More about Denatonium benzoate

Benzoic acid~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Benzoic acid

Phenoxyethanol~0.15–0.3%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Sodium benzoate~0.1–0.2%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Potassium sorbate~0.1–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Ingredient list view

Water, Alcohol denat., Hamamelis virginiana water, Pvm/ma decadiene crosspolymer, Salicylic acid, Dimethyl isosorbide, Glycerin, Polysorbate 20, Potassium hydroxide, Carnitine hcl, Vitex agnus-castus extract, Glutathione, Bisabolol, Niacinamide, Phytic acid, Glycolic acid, Ferulic acid, Leuconostoc/radish root ferment filtrate, Retinol, Chamomilla recutita flower extract, Aloe barbadensis leaf juice, Farnesol, Sodium pantothenate, Potassium azeloyl diglycinate, Camellia sinensis leaf extract, Phospholipids, Tocopheryl acetate, Saccharide isomerate, Sodium hyaluronate, Soy isoflavones, Zinc pca, Ethoxydiglycol, Octoxynol-9, Disodium edta, Potassium gluconate, Citric acid, Pentasodium pentetate, Bht, Bha, Sodium citrate, T-butyl alcohol, Sodium glycolate, Denatonium benzoate, Benzoic acid, Phenoxyethanol, Sodium benzoate, Potassium sorbate

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🇬🇧 Mankind (UK)30 ml

≈ $53.23 Out of stock

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🇬🇧 Cultbeauty (UK)30 ml

≈ $55.89 Out of stock

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🇬🇧 Lookfantastic (UK)30 ml

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Dr Dennis GrossDRx Blemish Solutions Breakout Clearing GelYOUR PRODUCT	GlytoneEnhance Brightening Solution	Medik8Blemish SOS Treatment	Perricone MDRetinol Treatment & Moisturizer
Match	—	68%	65%	64%
Price	—	$30.64	$28.17	—
Shared key ingredients	—	6 of 14	4 of 14	4 of 14
Key difference	—	Sodium Pca	—	Arginine
Irritancy	High	Medium	High	Medium
Drying alcohol	Contains drying alcohol	Contains drying alcohol	Contains drying alcohol	Contains drying alcohol
	View product	Shop	Shop	Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 33 studies and safety reviews.

1
Salicylic acid as a peeling agent: a comprehensive reviewncbi.nlm.nih.gov
2
Beta Hydroxy Acidsfda.gov
3
A review of toxicity from topical salicylic acid preparationssciencedirect.com
4
Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Studyonlinelibrary.wiley.com
5
Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositionspatents.google.com
6
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
7
Topically applied L-carnitine effectively reduces sebum secretion in human skinonlinelibrary.wiley.com
8
Glutathione as a skin whitening agent: Facts, myths, evidence and controversiesijdvl.com
9
Glutathione for skin lightening: a regnant myth or evidence-based verity?ncbi.nlm.nih.gov
10
Glutathione for skin lightening for dermatologists and cosmetologistsijord.com
11
α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammationresearchgate.net
12
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
13
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
14
Cosmetic and dermatologic use of alpha hydroxy acidsonlinelibrary.wiley.com
15
Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasmancbi.nlm.nih.gov
16
Photoprotective and antiinflammatory effects of topical glycolic acidncbi.nlm.nih.gov
17
Glycolic acid peel therapy – a current reviewncbi.nlm.nih.gov
18
Dual Effects of Alpha-Hydroxy Acids on the Skinmdpi.com
19
Ferulic Acid: Therapeutic Potential Through Its Antioxidant Propertyncbi.nlm.nih.gov
20
Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skinncbi.nlm.nih.gov
21
Antioxidant Properties of Ferulic Acid and Its Possible Applicationkarger.com
22
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
23
Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
24
A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
25
Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosaceancbi.nlm.nih.gov
26
A Preliminary Clinical Evaluation of a Topical Product for Reducing Slight Rosacea Imperfectionsdovepress.com
27
Azeloyl-Glycine: A new active in skin disequilibriumresearchgate.net
28
Formulation and evaluation of the cream made from potassium azeloyl diglycinate as an anti-agingresearchgate.net
29
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
30
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
31
Zinc L-pyrrolidone carboxylate inhibits the UVA-induced production of matrix metalloproteinase-1 by in vitro cultured skin fibroblasts, whereas it enhances their collagen synthesisonlinelibrary.wiley.com
32
Zinc Therapy in Dermatology: A Review hindawi.com
33
Amended final report of the safety assessment of t-Butyl Alcohol as used in cosmeticsncbi.nlm.nih.gov

Dr Dennis GrossDRx Blemish Solutions Breakout Clearing Gel

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