PRODUCT REVIEW
Dermatica Tretinoin, Niacinamide 4%, Azelaic Acid 4%
Appears in
11 routines
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Product summary
What can the product work for?
Works for
Does not work for
Anti-blemish
tretinoin
39% -
59%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
azelaic acid
3.5% -
5.2%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
niacinamide
5% -
7.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
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Anti-aging
tretinoin
39% -
59%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
niacinamide
5% -
7.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
gluconolactone
0.35% -
0.85%
Irritation risk:
Concentration: Insufficient!
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Evens skin tone
azelaic acid
3.5% -
5.2%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
niacinamide
5% -
7.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
tretinoin
39% -
59%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
Show more
Moisturizing
niacinamide
5% -
7.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
cholesterol
0.1% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
An emollient that is naturally found in skin
glycerin
1.3% -
1.9%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
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Anti-oxidation
azelaic acid
3.5% -
5.2%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
tretinoin
39% -
59%
Irritation risk:
Concentration: Effectiveness: HIGH
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
gluconolactone
0.35% -
0.85%
Irritation risk:
Concentration: Insufficient!
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Show more
Exfoliation
azelaic acid
3.5% -
5.2%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
gluconolactone
0.35% -
0.85%
Irritation risk:
Concentration: Insufficient!
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Honesty check
How honest is this product?
Promise | Can it deliver? |
---|---|
Anti-aging | |
Evens skin tone | |
Anti-blemish | |
Exfoliation |
Total Promises Fulfilled score:
87/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 0
Potential irritants
tretinoin
39% -
59%
Irritation risk:
Works for:
Evens skin tone,
Mattifying,
Anti-oxidation,
Anti-blemish,
Anti-aging
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
propylene glycol
1.4% -
2.1%
Irritation risk:
Works for:
Moisturizing
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
Show more
Comodogenic ingredients
No comodogenic ingredients detected
User reviews (0)
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WIMJ similarity score |
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Key ingredients |
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Irritancy | IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
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LOW
| IRRITANCY
LOW
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MEDIUM
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MEDIUM
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LOW
| IRRITANCY
LOW
| IRRITANCY
LOW
| IRRITANCY
MEDIUM
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MEDIUM
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LOW
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
5% -
7.5%
Irritation risk:
Works for:
Anti-blemish,
Evens skin tone,
Moisturizing,
Anti-aging,
Reduces irritation,
Reduces redness,
Anti-inflammatory,
Antibacterial
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
gluconolactone
0.35% -
0.85%
Irritation risk:
Works for:
Moisturizing,
Anti-aging,
Exfoliation,
Evens skin tone,
Anti-blemish,
Anti-oxidation
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Show more
Potential irritants
tretinoin
39% -
59%
Irritation risk:
Works for:
Evens skin tone,
Mattifying,
Anti-oxidation,
Anti-blemish,
Anti-aging
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
propylene glycol
1.4% -
2.1%
Irritation risk:
Works for:
Moisturizing
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
Show more
Comodogenic ingredients
We couldn't find any comodogenic ingredients in this product
All ingredients
tretinoin
39% -
59%
Irritation risk:
Works for:
Evens skin tone,
Mattifying,
Anti-oxidation,
Anti-blemish,
Anti-aging
Bioavailable form of Vitamin A that is the most effective known topical ingredients for reducing wrinkles, improving skin firmness, treating acne, as well as hyperpigmentation. It is not available over-the counter in many countries, including US and UK
niacinamide
5% -
7.5%
Irritation risk:
Works for:
Anti-blemish,
Evens skin tone,
Moisturizing,
Anti-aging,
Reduces irritation,
Reduces redness,
Anti-inflammatory,
Antibacterial
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
azelaic acid
3.5% -
5.2%
Irritation risk:
Works for:
Anti-oxidation,
Anti-blemish,
Evens skin tone,
Exfoliation
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
Show more
Ingredient list view
Tretinoin, Niacinamide, Azelaic acid, Water, Carthamus tinctorius oleosomes, Propylene glycol, Glycerin, Panthenol, Polyacrylate-13, Polyisobutene, Sodium carbomer, Gluconolactone, Polysorbate 20, Sorbitan isostearate, Benzoic acid, Sorbic acid, Sodium benzoate, Propanediol, Tocopheryl acetate, Ceramide ap, Ceramide eop, Ceramide np, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Xanthan gum, Carbomer, Sodium hyaluronate
Sources
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Glycerol and the skin: holistic approach to its origin and functions
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids
- Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Light
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Hyaluronic acid: A key molecule in skin aging