Centellian24 Expert Madeca Cream Active Renew PDRN 50ml

Centellian24 Expert Madeca Cream Active Renew PDRN 50ml

Efficacy100/100IrritancyHigh
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Works for

2 of 2 advertised claims delivered

Moisturizing
40 ingredients credited for this claim
Strong support
What the product description says
“Fortifies skin barrier and replenishes moisture levels with Caffeine, Glutathione and Hyaluronic Acid.”
Source: Lila Beauty

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: aspartic acid, glutamic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, beta-sitosterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, phytosphingosine

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.15–0.3%
Helianthus annuus seed waxKey active· EmollientEffect: HighHelps soften the upper layer of the skin and support skin's barrier function while creating a thicker product consistency~0.3–0.5%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.25–0.45%
Polyglycerin-3Key active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.25–0.5%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.25–0.45%
Vinyl dimethiconeKey active· EmollientEffect: HighA type of silicone that helps to create a nice product texture and soften the upper layer of the skin~0.95–1.2%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.3–0.55%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.3–0.6%
Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.15–0.3%
Beta-sitosterolKey active· EmollientEffect: HighA phytosterol that can support skin's barrier function and help the skin stay hydrated~0.3–0.55%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.1–3.8%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.5%
Collagen amino acidsKey activeEffect: HighHelp attract water to the upper layer of the skin, soften it and support the skin barrier function~0.2–0.4%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.25–0.45%
Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.15–0.3%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.3–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~5–6.1%
GlycoproteinsKey activeEffect: High~0.25–0.4%
Laminaria japonica extractKey activeEffect: HighSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties~0.25–0.45%
Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.35–0.65%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%
PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%
PhytosterolsKey active· EmollientEffect: HighLipids that work as an emollient and can be helpful in repairing skin barrier function~0.3–0.55%
C10-18 triglyceridesKey active· EmollientEffect: MediumHelps soften the skin and attract water to its upper layer. Helps create nice product texture~0.3–0.5%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.3–0.55%
Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.25–0.5%
Glyceryl stearatesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.3–0.55%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.75–1.15%
Ulmus davidiana root extractKey activeEffect: MediumA plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skin~0.2–0.4%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.45%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.3–0.55%
Pentaerythrityl tetraethylhexanoate· EmollientEffect: LowUsed to create a nice product consistency while softening the upper layer of the skin~1.6–2%
Centella asiatica extractUnder-dosedEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.65%
PanthenolUnder-dosedEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.25–0.45%
Aloe barbadensis leaf extractEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.25–0.5%
Rosa damascena flower waterEffect: Low, below effective doseUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating~0.5–0.8%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Evens skin tone
3 ingredients credited for this claim
Strong support
What the product description says
“Reduces skin hyperpigmentation while improving the skin barrier.”
Source: Lila Beauty

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.3–0.6%
Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.25–0.45%
Anti-oxidation
Not advertised by the brand · 12 ingredients credited for this claim
Strong support

This product contains antioxidants (asiaticoside, glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.3–0.6%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.3–0.6%
CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.3–0.5%
Coptis japonica root extractEffect: LowA plant extract that might have some anti-oxidant properties~0.25–0.45%
Ulmus davidiana root extractEffect: LowA plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skin~0.2–0.4%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.25–0.45%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.65%
Rosmarinus officinalis leaf oilEffect: Low, below effective doseA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin~0.25–0.45%
Rosa damascena flower waterEffect: Low, below effective doseUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating~0.5–0.8%
Anthemis nobilis flower oilEffect: Low, below effective doseAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin~0.2–0.4%
Anti-aging
Not advertised by the brand · 8 ingredients credited for this claim
Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, aspartic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.15–0.3%
AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.3–0.6%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%
Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.25–0.45%
Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.65%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Anti-blemish
Not advertised by the brand · 3 ingredients credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%
PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%
Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.65%

Can it cause trouble?

Irritancy
7 strong irritants: Rosa damascena flower water, Lavandula angustifolia oil + 5 more — patch-test recommended
High risk
We flagged 30 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosa damascena flower waterUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritatingHigh~0.5–0.8%est.
Ulmus davidiana root extractA plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skinHigh~0.2–0.4%est.
Coptis japonica root extractA plant extract that might have some anti-oxidant propertiesHigh~0.25–0.45%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.25–0.45%est.
Citrus aurantium bergamia fruit oilA plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivityHigh~0.25–0.45%est.
Citrus aurantium dulcis peel oilAn essentil oil from orange peel. Potential allergen and can be irritatingHigh~0.25–0.45%est.
Rosmarinus officinalis leaf oilA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skinHigh~0.25–0.45%est.
Anthemis nobilis flower oilAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skinHigh~0.2–0.4%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.25–0.45%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.1–0.15%est.
LinaloolA fragrance. Can be irritatingHigh~0.1–0.15%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.1–3.8%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.5–0.75%est.
Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.35–0.65%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.3–0.6%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.45–0.65%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.3–0.6%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.3–0.5%est.
PhytosterolsLipids that work as an emollient and can be helpful in repairing skin barrier functionMedium~0.3–0.55%est.
Aloe barbadensis leaf extractTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.25–0.5%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.25–0.45%est.
1,2-hexanediolA preservativeMedium~0.25–0.45%est.
Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.3–0.55%est.
Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.25–0.45%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.3–0.55%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.25–0.5%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.25–0.5%est.
EthylhexylglycerinA preservativeMedium~0.25–0.5%est.
Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.25–0.5%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Laminaria japonica extractSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties3/5~0.25–0.45%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.75–1.15%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~5–6.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dipropylene glycol~4–4.9%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Caprylic/capric triglyceride~3.1–3.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Hydrogenated poly(c6-12 olefin)~2.3–2.8%
Formula
Glyceryl stearate/acetate~1.9–2.3%
Formula
Pentaerythrityl tetraethylhexanoate~1.6–2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product consistency while softening the upper layer of the skin

More about Pentaerythrityl tetraethylhexanoate
Niacinamide~1.4–1.7%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Methyl trimethicone~1.1–1.4%
Formula
Irritation risk
Low

A type of silicone that helps create a silky product finish and dissolve other ingredients

More about Methyl trimethicone
Vinyl dimethicone~0.95–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that helps to create a nice product texture and soften the upper layer of the skin

More about Vinyl dimethicone
Cetearyl alcohol~0.75–1.15%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Rosa damascena flower water~0.5–0.8%
Irritant · high
Irritation risk
High
Works for
MoisturizingAnti-oxidation

Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating

More about Rosa damascena flower water
Polyglyceryl-10 laurate~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Sodium dna~0.4–0.65%
Formula
Irritation risk
Low
More about Sodium dna
Madecassic acid~0.35–0.65%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid
Asiaticoside~0.3–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Centella asiatica extract~0.45–0.65%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Glutathione~0.3–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingEvens skin tone

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
Caffeine~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Beta-sitosterol~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A phytosterol that can support skin's barrier function and help the skin stay hydrated

More about Beta-sitosterol
Phytosterols~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Lipids that work as an emollient and can be helpful in repairing skin barrier function

More about Phytosterols
Laminaria japonica extract~0.25–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Seaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties

More about Laminaria japonica extract
Aloe barbadensis leaf extract~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf extract
Dioscorea japonica root extract~0.2–0.4%
Formula
Ulmus davidiana root extract~0.2–0.4%
Key activeIrritant · high
Irritation risk
High
Works for
MoisturizingAnti-oxidation

A plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skin

More about Ulmus davidiana root extract
Viola mandshurica flower extract~0.25–0.5%
Formula
Sodium hyaluronate dimethylsilanol~0.25–0.45%
Formula
Potassium hyaluronate~0.25–0.45%
Formula
Hydrolyzed hyaluronic acid~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Hydrolyzed sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Hyaluronic acid~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Potassium hyaluronate~0.25–0.45%
Formula
Sodium hyaluronate crosspolymer~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
Hydroxypropyltrimonium hyaluronate~0.25–0.5%
Formula
1,2-hexanediol~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Panthenol~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
C10-18 triglycerides~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the skin and attract water to its upper layer. Helps create nice product texture

More about C10-18 triglycerides
Sodium stearoyl glutamate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate
Sodium polyacryloyldimethyl taurate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate
Butylene glycol~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Jojoba esters~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Glyceryl stearates~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Glyceryl stearates
Hydroxyacetophenone~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Cetyl alcohol~0.3–0.55%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Stearyl alcohol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Behenyl alcohol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Helianthus annuus seed wax~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and support skin's barrier function while creating a thicker product consistency

More about Helianthus annuus seed wax
Coptis japonica root extract~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Coptis japonica root extract
Ethylhexylglycerin~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Lavandula angustifolia oil~0.25–0.45%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Citrus aurantium bergamia fruit oil~0.25–0.45%
Irritant · high
Irritation risk
High

A plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivity

More about Citrus aurantium bergamia fruit oil
Olea europaea fruit oil~0.25–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil
Citrus aurantium dulcis peel oil~0.25–0.45%
Irritant · high
Irritation risk
High

An essentil oil from orange peel. Potential allergen and can be irritating

More about Citrus aurantium dulcis peel oil
Xanthan gum~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Rosmarinus officinalis leaf oil~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationAntibacterial

A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin

More about Rosmarinus officinalis leaf oil
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Adenosine~0.25–0.45%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Sorbitan isostearate~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Polyglycerin-3~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Polyglycerin-3
Anthemis nobilis flower oil~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-inflammatory

An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin

More about Anthemis nobilis flower oil
Cyanocobalamin~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Ascorbic acid~0.25–0.45%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Tocopherol~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ceramide np~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Glycoproteins~0.25–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Glycoproteins
Phytosphingosine~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-blemish

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine
Hydrogenated lecithin~0.25–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Collagen amino acids~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Help attract water to the upper layer of the skin, soften it and support the skin barrier function

More about Collagen amino acids
Hydrolyzed elastin~0.25–0.45%
Formula
Aspartic acid~0.15–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid
Glycine~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine
Glutamic acid~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid
Limonene~0.1–0.15%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.1–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Ingredient list view

Water, Glycerin, Dipropylene glycol, Caprylic/capric triglyceride, Hydrogenated poly(c6-12 olefin), Glyceryl stearate/acetate, Pentaerythrityl tetraethylhexanoate, Niacinamide, Methyl trimethicone, Vinyl dimethicone, Cetearyl alcohol, Rosa damascena flower water, Polyglyceryl-10 laurate, Sodium dna, Madecassic acid, Asiaticoside, Centella asiatica extract, Glutathione, Caffeine, Beta-sitosterol, Phytosterols, Laminaria japonica extract, Aloe barbadensis leaf extract, Dioscorea japonica root extract, Ulmus davidiana root extract, Viola mandshurica flower extract, Sodium hyaluronate dimethylsilanol, Potassium hyaluronate, Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate, Hyaluronic acid, Potassium hyaluronate, Sodium hyaluronate crosspolymer, Hydroxypropyltrimonium hyaluronate, 1,2-hexanediol, Panthenol, C10-18 triglycerides, Sodium stearoyl glutamate, Sodium polyacryloyldimethyl taurate, Butylene glycol, Jojoba esters, Glyceryl stearates, Hydroxyacetophenone, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Cetyl alcohol, Stearyl alcohol, Behenyl alcohol, Helianthus annuus seed wax, Coptis japonica root extract, Ethylhexylglycerin, Lavandula angustifolia oil, Citrus aurantium bergamia fruit oil, Olea europaea fruit oil, Citrus aurantium dulcis peel oil, Xanthan gum, Rosmarinus officinalis leaf oil, Disodium edta, Adenosine, Sorbitan isostearate, Polyglycerin-3, Anthemis nobilis flower oil, Cyanocobalamin, Ascorbic acid, Tocopherol, Ceramide np, Glycoproteins, Phytosphingosine, Hydrogenated lecithin, Collagen amino acids, Hydrolyzed elastin, Aspartic acid, Glycine, Glutamic acid, Limonene, Linalool

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Centellian24Expert Madeca Cream Active Renew PDRN 50mlYOUR PRODUCTTOSOWOONGDexpanthenol CreamROUND LABPine Calming Cica Cream Plus 60mlMISSHAAtelo Collagen 500 Power Plumping Cream
Match—86%86%84%
Price$30.34$19.10−$11.24$26.37−$3.97$22.00−$8.34
Shared key ingredients—12 of 3016 of 3013 of 30
Key difference—MadecassosideMadecassosideArginine/Lysine Polypeptide
Irritancy High Medium Medium High
Drying alcohol— Contains drying alcohol ——
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Product summary

"Centellian24 - Buy Centellian24 Expert Madeca Cream Active Renew PDRN in Australia - Korean Skincare Online" is a well-rounded moisturizing product. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (aspartic acid, glutamic acid, glycerin, glycine and hyaluronic acid) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide np, phytosphingosine, beta-sitosterol, helianthus annuus seed wax and jojoba esters in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.25% - 0.45%) it cannot have a noticeable benefit for the skin.
  • As a plus, this moisturizer also contains Ceramides (phytosphingosine 0.25% - 0.50% and ceramide np 0.25% - 0.50%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiaticoside 0.30% - 0.60% and madecassic acid 0.35% - 0.65% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e and vitamin c

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 22.95A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 53 studies and safety reviews.

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Centellian24 Expert Madeca Cream Active Renew PDRN 50ml
Centellian24Expert Madeca Cream Active Renew PDRN 50ml

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