ZO Skin Health Neck Complex Anti-Aging + Brightening Serum
Works for
Anti-agingCaprooyl tetrapeptide-3, Arginine/lysine polypeptide + 1 moreMay help
“This dual-action serum is made for the neck and décolleté, visibly smoothing crepey skin and deep horizontal lines, firming for a more lifted looking and visibly defined contour, and brightening uneven tone.”
This product contains arginine/lysine polypeptide, caprooyl tetrapeptide-3. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Evens skin toneGlycyrrhiza uralensis root extractNot delivered
“Multi-faceted formula delivers visible renewal of the neck & décolleté. Clinically shown to firm + tighten the appearance of skin for a visibly more defined neck contour, while delivering a more even-looking skin tone.”
This product contains ingredients (glycyrrhiza uralensis root extract) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.
MoisturizingSide benefit · Caprooyl tetrapeptide-3, Arginine/lysine polypeptide + 13 moreWorks well
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
dextran, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: arginine/lysine polypeptide, caprooyl tetrapeptide-3
Can it cause trouble?
Irritancy2 strong irritants: Melilotus officinalis extract, Lavandula stoechas extractMedium risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
Be the first — your take helps the next person decide.
Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Dimethicone~6.3–7.7%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeButylene glycol~4.1–5%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolGlycerin~3.2–3.9%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinCaprylyl methicone~2.4–2.9%
- Irritation risk
- Low
A type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin
More about Caprylyl methiconeDimethicone/peg-10/15 crosspolymer~1.9–2.3%
Peg-12 dimethicone/ppg-20 crosspolymer~1.7–2.1%
- Irritation risk
- Low
Helps water and oil mix together
More about Peg-12 dimethicone/ppg-20 crosspolymerDimethicone/vinyl dimethicone crosspolymer~1.5–1.8%
- Irritation risk
- Low
Used to stabilize product formulations and create a nice product texture
More about Dimethicone/vinyl dimethicone crosspolymerSodium chloride~1.3–1.6%
- Irritation risk
- Low
Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures
More about Sodium chlorideCaprylic/capric triglyceride~1–1.3%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideLactobacillus ferment~0.7–1%
- Irritation risk
- Low
A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative
More about Lactobacillus fermentScutellaria baicalensis root extract~0.45–0.65%
- Irritation risk
- High
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
More about Scutellaria baicalensis root extractPentylene glycol~0.55–0.85%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolHydrolyzed sericin~0.45–0.7%
- Irritation risk
- Low
Phospholipids~0.45–0.65%
- Irritation risk
- Low
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
More about PhospholipidsSodium citrate~0.4–0.65%
- Irritation risk
- Medium
Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products
More about Sodium citrateBuddleja davidii meristem cell culture~0.4–0.6%
- Irritation risk
- Low
Cordyceps militaris mycelium extract~0.3–0.6%
- Irritation risk
- Low
Glycyrrhiza uralensis root extract~0.3–0.55%
- Irritation risk
- Medium
Licorice root extract. Might be helpful in reducing hyperpigmentation
More about Glycyrrhiza uralensis root extractMelilotus officinalis extract~0.25–0.5%
- Irritation risk
- High
A plant extract that might have some anti-oxidant properties. Can be used as a fragrance and can be irritating
More about Melilotus officinalis extractDiglucosyl gallic acid~0.25–0.5%
- Irritation risk
- Low
Dipropylene glycol~0.25–0.45%
- Irritation risk
- Low
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
More about Dipropylene glycolXanthan gum~0.25–0.45%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumPhenoxyethanol~0.25–0.45%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolPichia ferment lysate filtrate~0.25–0.45%
- Irritation risk
- Low
Caprylyl glycol~0.25–0.5%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolLavandula stoechas extract~0.25–0.45%
Hexylene glycol~0.2–0.4%
- Irritation risk
- Medium
Helps create a more spreadable product texture
More about Hexylene glycolPotassium sorbate~0.25–0.45%
Ethylhexylglycerin~0.2–0.4%
Tocopherol~0.2–0.4%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolGlyceryl caprylate~0.25–0.5%
- Irritation risk
- Low
An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products
More about Glyceryl caprylateLactic acid/glycolic acid copolymer~0.2–0.35%
- Irritation risk
- Low
Phenylpropanol~0.2–0.35%
- Irritation risk
- High
Helps mask the smell of other ingredients and helps preserve the product formulation
More about PhenylpropanolPolyvinyl alcohol~0.2–0.35%
Caprooyl tetrapeptide-3~0.2–0.35%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Caprooyl tetrapeptide-3Dextran~0.1–0.2%
- Irritation risk
- Low
Helps attract water to the most upper layer of the skin. Derived from sugar
More about DextranArginine/lysine polypeptide~0.1–0.15%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Arginine/lysine polypeptideIngredient list view
Water, Dimethicone, Butylene glycol, Glycerin, Caprylyl methicone, Dimethicone/peg-10/15 crosspolymer, Peg-12 dimethicone/ppg-20 crosspolymer, Dimethicone/vinyl dimethicone crosspolymer, Sodium chloride, Caprylic/capric triglyceride, Lactobacillus ferment, Scutellaria baicalensis root extract, Pentylene glycol, Hydrolyzed sericin, Phospholipids, Sodium citrate, Buddleja davidii meristem cell culture, Cordyceps militaris mycelium extract, Glycyrrhiza uralensis root extract, Melilotus officinalis extract, Diglucosyl gallic acid, Dipropylene glycol, Xanthan gum, Phenoxyethanol, Pichia ferment lysate filtrate, Caprylyl glycol, Lavandula stoechas extract, Hexylene glycol, Potassium sorbate, Ethylhexylglycerin, Tocopherol, Glyceryl caprylate, Lactic acid/glycolic acid copolymer, Phenylpropanol, Unknown, Polyvinyl alcohol, Caprooyl tetrapeptide-3, Dextran, Unknown, Arginine/lysine polypeptide
Compare prices
Retailers ranked by price — lowest first.
Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| ZO Skin HealthNeck Complex Anti-Aging + Brightening SerumYOUR PRODUCT | NeolastinFace & Neck Regenerative Serum | Medik8LIQUID PEPTIDES ADVANCED MP | Elizabeth ArdenPrevage Advanced Daily Serum | |
|---|---|---|---|---|
| Match | — | 40% | 38% | 37% |
| Price | $155.00 | $149.00−$6.00 | $93.28−$61.72 | $119.40−$35.60 |
| Shared key ingredients | — | 3 of 8 | 5 of 8 | 4 of 8 |
| Key difference | — | Anhydroxylitol | Copper Palmitoyl Heptapeptide-14 | Salicylic Acid |
| Irritancy | Medium | Low | Medium | High |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Skincall Daily Triple SerumAlgenist ELEVATE Firming & Lifting Contouring Serum
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 12 studies and safety reviews.
- 1
- 2Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 3
- 4
- 5
- 6Use of Probiotics for Dermal Applicationsresearchgate.net
Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.