ZENii Stem Cell Renewal Cream
Something wrong? Edit here- Anti-aging
- Exfoliation
- Moisturizing
- +2 more
- gluconolactone
- ceramide np
- caprylic/capric triglyceride
- +6 more
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Formula review
Promise
What does the product description say?WIMJ summary
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains gluconolactone.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH |
WIMJ summary
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH |
WIMJ summary
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH |
Promise
What does the product description say?WIMJ summary
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
HIGH | |||
HIGH |
WIMJ summary
This product contains antioxidants (gluconolactone, squalene) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
MEDIUM
| |||
MEDIUM
|
Potential irritants

Ingredient | Irritancy | Skin Benefit |
---|---|---|
caprylic/capric triglyceride | ||
citrus aurantium dulcis callus culture extract | ||
gluconolactone |
Ingredients by volume
Ingredient | Estimated concentration |
---|---|
Plain old water
| 40% - 60% |
An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast
| 5.9% - 8.9% |
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
| 4.4% - 6.6% |
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Questions
Skincare resources
Scientific Sources
- Squalene and its potential clinical uses
- Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology
- Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxides
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Glycerol and the skin: holistic approach to its origin and functions
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids