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Outlet ZENii Stem Cell Renewal Cream - CLEARANCE
Outlet

Outlet ZENii Stem Cell Renewal Cream - CLEARANCE

Efficacy50/100IrritancyMedium
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Works for

0 of 1 advertised claim delivered

Anti-aging
1 ingredient credited for this claim
Limited support
What the product description says
“The state-of-the-art formula supports skin’s natural collagen production, protects against free radical damage, renews and reorganises collagen fibres and stimulates the skin’s own stem cells.”
Source: Face the future

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

This ingredient squalene might be able to help neutralize free radicals in skin and help it fight off some of the sun damage.

GluconolactoneUnder-dosedEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.7%
Anti-oxidation
Not advertised by the brand · 2 ingredients credited for this claim
Moderate support

This product contains antioxidants (squalene) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

SqualeneKey activeEffect: MediumAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~6.1–9.1%
GluconolactoneUnder-dosedEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.7%
Moisturizing
Not advertised by the brand · 9 ingredients credited for this claim
Good support

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.2–3.4%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.8–2.7%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~2.9–4.4%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.8–1.2%
SqualeneKey active· Emollient, OcclusiveEffect: HighAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~6.1–9.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.4–2.1%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~4.3–6.5%
Calcium gluconate· HumectantEffect: LowHelps attract water to the upper layer of the skin and helps to improve appearance of the product~0.15–0.6%
GluconolactoneUnder-dosedEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.7%

Can it cause trouble?

Irritancy
1 strong irritant: Citrus aurantium dulcis callus culture extract
Medium risk
We flagged 5 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Citrus aurantium dulcis callus culture extract—High~1.1–1.7%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.2–3.4%est.
GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.15–0.7%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.1–0.4%est.
EthylhexylglycerinA preservativeMedium~0.05–0.2%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~2.9–4.4%est.
SqualeneAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast2/5~6.1–9.1%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Squalene~6.1–9.1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
MoisturizingAnti-oxidation

An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast

More about Squalene
Cyclopentasiloxane~4.3–6.5%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Isopropyl myristate~2.9–4.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Caprylic/capric triglyceride~2.2–3.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Dimethicone~1.8–2.7%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glycerin~1.4–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Citrus aurantium dulcis callus culture extract~1.1–1.7%
Irritant · high
Irritation risk
High
More about Citrus aurantium dulcis callus culture extract
Sodium hyaluronate~0.8–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Xanthan gum~0.5–1.2%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Gluconolactone~0.15–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-agingEvens skin toneExfoliationAnti-blemishAnti-oxidation

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone
Calcium gluconate~0.15–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and helps to improve appearance of the product

More about Calcium gluconate
Polysorbate 60~0.1–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Phenoxyethanol~0.1–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Squalene, Cyclopentasiloxane, Isopropyl myristate, Caprylic/capric triglyceride, Dimethicone, Glycerin, Citrus aurantium dulcis callus culture extract, Sodium hyaluronate, Xanthan gum, Sodium benzoate, Gluconolactone, Calcium gluconate, Polysorbate 60, Phenoxyethanol, Ethylhexylglycerin

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Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
OutletZENii Stem Cell Renewal Cream - CLEARANCEYOUR PRODUCTZENiiStem Cell Renewal CreamSVRTopialyse Moisturising Face + Body Cream for Dry, Sensitive + Eczema-Prone Skin of All AgesNeogenisisBarrier Renewal Cream
Match—75%63%63%
Price$59.49$99.15+$39.66$17.00−$42.49$197.50+$138.01
Shared key ingredients—8 of 84 of 83 of 8
Key difference——Camelina Sativa Seed OilPanthenol
Irritancy Medium Medium Low Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

  1. 1
    Squalene and its potential clinical useseuropepmc.org
  2. 2
    Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology mdpi.com
  3. 3
    Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxidesonlinelibrary.wiley.com
  4. 4
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  5. 5
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  6. 6
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
Outlet ZENii Stem Cell Renewal Cream - CLEARANCE
OutletZENii Stem Cell Renewal Cream - CLEARANCE
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