The Chemistry Brand Extreme Hydration Complex Hand Cream

The Chemistry Brand Extreme Hydration Complex Hand Cream

Efficacy100/100IrritancyHigh

Works for

Moisturizing
Panthenol, Hydrolyzed yeast extract + 13 more
Works well
What the product description says
“Containing a 24% active ingredient, ultra-concentrated formula, the cream contains plant and marine extracts which provide deep and long-lasting hydration.”
Source: Mankind

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, betaine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cyclopentasiloxane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.25–0.5%
Hydrolyzed yeast extractKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~2.3–2.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.35–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.55%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~0.3–0.55%
Cetearyl dimethicone crosspolymerKey activeEffect: MediumHelps create a nice product texture and soften the upper layer of the skin~0.3–0.5%
ProlineKey activeEffect: Medium~0.3–0.5%
Tremella fuciformis sporocarp extractKey active· HumectantEffect: HighMushroom extract that helps attract water to the upper layer of the skin~0.25–0.5%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.25–0.4%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.5%
AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.25–0.5%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.4–0.65%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.55%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.3–0.55%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.6%
Anti-aging
Not advertised by the brand · Serine
May help

This product contains serine. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.5%

Can it cause trouble?

Irritancy
13 strong irritants: Parfum, Alpha-isomethyl ionone + 11 more — patch-test recommended
High risk
We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.25–0.45%est.
Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.25–0.4%est.
Benzyl benzoateFragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritatingHigh~0.25–0.45%est.
Benzyl cinnamateFragrance. Can be irritatingHigh~0.25–0.45%est.
Benzyl salicylateA fragrance. Is a likely irritantHigh~0.25–0.45%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.25–0.45%est.
CitronellolA fragrance. Can be irritatingHigh~0.25–0.45%est.
EugenolA fragrance. Is a likely irritantHigh~0.25–0.45%est.
GeraniolA fragrance. Can be irritatingHigh~0.25–0.45%est.
HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.25–0.45%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.25–0.45%est.
FarnesolAdded to create a nice product smell. Can be irritatingHigh~0.15–0.3%est.
LinaloolA fragrance. Can be irritatingHigh~0.1–0.15%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~3.2–3.9%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.45–0.7%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.5%est.
EthylhexylglycerinA preservativeMedium~0.25–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.55%est.
Potassium sorbateA preservativeMedium~0.25–0.5%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Dimethicone~5.4–6.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Propanediol~4.2–5.2%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~3.2–3.9%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Hydrolyzed yeast extract~2.3–2.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties

More about Hydrolyzed yeast extract
Cetearyl dimethicone crosspolymer~1.9–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps create a nice product texture and soften the upper layer of the skin

More about Cetearyl dimethicone crosspolymer
Panthenol~1.6–1.9%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Isohexadecane~1.5–1.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Polysilicone-11~1.2–1.5%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Glycerin~1–1.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Alanine~0.65–1%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Proline~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Proline
Serine~0.5–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Pseudoalteromonas ferment extract~0.45–0.7%
Formula
Tremella fuciformis sporocarp extract~0.45–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Mushroom extract that helps attract water to the upper layer of the skin

More about Tremella fuciformis sporocarp extract
Polyglucuronic acid~0.45–0.65%
Formula
Irritation risk
Low

Often used to support the moisturization effect of polysaccharides (contained, for example, in yeast extract)

More about Polyglucuronic acid
Polysorbate 60~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Cyclopentasiloxane~0.45–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Cyclotetrasiloxane~0.35–0.65%
Formula
Xanthan gum~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Cetyl hydroxyethylcellulose~0.3–0.55%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize formulations

More about Cetyl hydroxyethylcellulose
Lecithin~0.3–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Betaine~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Sodium phosphate~0.25–0.5%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Sodium phosphate
Sodium hydroxide~0.25–0.5%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Citric acid~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ethylhexylglycerin~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Caprylyl glycol~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Potassium sorbate~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Parfum~0.25–0.45%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Phenoxyethanol~0.25–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Alpha-isomethyl ionone~0.25–0.4%
Irritant · high
Irritation risk
High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone
Benzyl benzoate~0.25–0.45%
Irritant · high
Irritation risk
High

Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating

More about Benzyl benzoate
Benzyl cinnamate~0.25–0.45%
Irritant · high
Irritation risk
High

Fragrance. Can be irritating

More about Benzyl cinnamate
Benzyl salicylate~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Benzyl salicylate
Citral~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Citronellol~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Eugenol~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Eugenol
Geraniol~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Hydroxycitronellal~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal
Limonene~0.25–0.45%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Water~0.25–0.5%
Formula
Irritation risk
Low

Plain old water

More about Water
Dimethicone~0.35–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Propanediol~0.3–0.55%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.3–0.5%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Cetearyl dimethicone crosspolymer~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps create a nice product texture and soften the upper layer of the skin

More about Cetearyl dimethicone crosspolymer
Panthenol~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Isohexadecane~0.4–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Polysilicone-11~0.3–0.55%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Glycerin~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Disodium acetyl glucosamine phosphate~0.25–0.5%
Formula
Pseudoalteromonas ferment extract~0.25–0.5%
Formula
Cyclopentasiloxane~0.3–0.55%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Cyclotetrasiloxane~0.3–0.55%
Formula
Potassium sorbate~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Tremella fuciformis sporocarp extract~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Mushroom extract that helps attract water to the upper layer of the skin

More about Tremella fuciformis sporocarp extract
Xanthan gum~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ethylhexylglycerin~0.3–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Caprylyl glycol~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Citric acid~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Alanine~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Proline~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Proline
Serine~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Sodium phosphate~0.25–0.5%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Sodium phosphate
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Phenoxyethanol~0.25–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polysorbate 60~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Betaine~0.25–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Parfum~0.2–0.35%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Citral~0.2–0.35%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Citronellol~0.15–0.3%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Eugenol~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Eugenol
Farnesol~0.15–0.3%
Irritant · high
Irritation risk
High

Added to create a nice product smell. Can be irritating

More about Farnesol
Geraniol~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Limonene~0.1–0.2%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.1–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Ingredient list view

Water, Dimethicone, Propanediol, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Hydrolyzed yeast extract, Cetearyl dimethicone crosspolymer, Panthenol, Isohexadecane, Polysilicone-11, Glycerin, Alanine, Proline, Serine, Pseudoalteromonas ferment extract, Tremella fuciformis sporocarp extract, Polyglucuronic acid, Polysorbate 60, Cyclopentasiloxane, Cyclotetrasiloxane, Xanthan gum, Cetyl hydroxyethylcellulose, Lecithin, Betaine, Sodium phosphate, Sodium hydroxide, Citric acid, Sodium benzoate, Ethylhexylglycerin, Caprylyl glycol, Potassium sorbate, Parfum, Phenoxyethanol, Chlorphenesin, Alpha-isomethyl ionone, Benzyl benzoate, Benzyl cinnamate, Benzyl salicylate, Citral, Citronellol, Eugenol, Geraniol, Hydroxycitronellal, Limonene, Water, Dimethicone, Propanediol, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Cetearyl dimethicone crosspolymer, Panthenol, Isohexadecane, Polysilicone-11, Glycerin, Disodium acetyl glucosamine phosphate, Pseudoalteromonas ferment extract, Cyclopentasiloxane, Cyclotetrasiloxane, Potassium sorbate, Tremella fuciformis sporocarp extract, Xanthan gum, Ethylhexylglycerin, Caprylyl glycol, Chlorphenesin, Citric acid, Alanine, Proline, Serine, Sodium phosphate, Sodium hydroxide, Phenoxyethanol, Polysorbate 60, Betaine, Parfum, Citral, Citronellol, Eugenol, Farnesol, Geraniol, Limonene, Linalool

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🇦🇺 Recreate Yourself (AU)100 ml
≈ $24.05
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🇬🇧 Lookfantastic (UK)100 ml
≈ $25.42
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🇬🇧 Mankind (UK)100 ml
≈ $25.42
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
The Chemistry BrandExtreme Hydration Complex Hand CreamYOUR PRODUCTSkintegraCica-CeraHolika HolikaPeach Date Perfumed Hand CreamUNICATFortune Cat Hand Cream Vanilla
Match—57%57%57%
Price——$5.35$8.40
Shared key ingredients—4 of 105 of 104 of 10
Key difference—MadecassosideButyrospermum Parkii ButterMineral Oil
Irritancy High Medium Medium Medium
Drying alcohol————
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Product summary

"The Chemistry Brand - Extreme Hydration Complex Hand Cream" is effective for: Moisturizing

This moisturizer could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • An effective concentration of Panthenol (pro-vitamin B5) - about 1.60% - 1.90%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

Price

The product retails for 18.99$ in the United States, for 26.50CA$ in Canada, for 35.00A$ in Australia and for 18.99£ in the United Kingdom.

For a detailed price comparison: click here.

The Chemistry Brand Extreme Hydration Complex Hand Cream
The Chemistry BrandExtreme Hydration Complex Hand Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.