Works for:
based on ingredients and %- Sun protection
- Anti-aging
- Moisturizing
- Evens skin tone
Can it cause trouble?
- Irritation risk: low
- Comedogenic risk ingredients: 3
Key actives
Product Summary
Based on the ingredient list, we assess that "SkinMedica - Total Defense and Repair SPF 50" can provide reliable sun protection. We love that it can protect from both UVA and UVB rays (not all sunscreens with SPF ratings give UVA protection. UVA rays do not cause sunburn, but still damage our skin and lead to early aging).
Because it includes good moisturizing ingredients, it can also work as a hydrating day cream. Like all broad-spectrum sunscreens, this product helps prevent early signs of aging.
Sunscreen filters
This sunscreen uses a mixture of both mineral and organic (so-called "chemical") UV filters. The organic filters in the product are: octinoxate, octisalate and homosalate. As for the mineral filters, this sunscreen uses zinc oxide.
Irritation risk
There are actives in this product that can be irritating. We assess the overall irritancy of this product to be low. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 61.20$ up to 68.00$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
With use of this anti-aging sunscreen you will notice.
Source: SkincareRX
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
This product can also help prevent early signs of skin aging because it offers a good level of broad spectrum sun protection. Sun damage is the main cause of premature skin aging, and protecting your skin from the sun is the best anti-aging strategy.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Anti-oxidation
This product contains antioxidants (polygonum aviculare extract, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - camellia sinensis leaf extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin
Mushroom extract that helps attract water to the upper layer of the skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Evens skin tone
What does the product description say?
Improved skin texture and balanced skin tone.
Source: SkincareRX
This product offers broad spectrum sun protection. It means that it can prevent hyperpigmentation and help keep the skin tone even (sun damage is the main factor causing age spots, darkening of post-acne marks and other discolorations).
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Moisturizing
What does the product description say?
Improved skin texture and balanced skin tone.
Source: SkincareRX
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
betaine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Mushroom extract that helps attract water to the upper layer of the skin
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
Helps attract water to the upper layer of the skin and improves the product texture
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Non-drying alcohol. Used to stabilize other ingredients and is an emollient
Helps preserve products and creates a nice product texture
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Sun protection
This product offers a good level of protection against both UVB and UVA rays.
This sunscreen uses organic (so-called "chemical") sunscreen filters. Organic, or "chemical" filters usually provide reliable sun protection and rarely leave a white cast. Sunscreens with organic filters can sting eyes.
A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant
Octinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritating
A weak sunscreen that offers some protection against the sun rays that cause sunburn (UVB), but does not offer meaningful protection against protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen. When used in low concentrations, helps to stabilize the product formulation
Octisalate. A UV filter. It offers some protection against the sun rays that cause sunburn (UVB), but does not protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Sun protection | |
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 90/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 SkinMedica Total Defense and Repair SPF 50 | Current | $-1.00 | |
Replenix Tinted Oil-Free Face Sunscreen SPF50+ | 73% | $35.00 | |
La Roche-Posay Anthelios UV Correct SPF 70 Daily Anti-Aging Face Sunscreen | 73% | $32.99 | |
 DRMTLGY Broad Spectrum SPF 45 | 71% | $25.00 | |
 Altruist Face Fluid Sunscreen SPF30 | 70% | $7.70 | |
 NEEDLY Mild non-nano sun milk SPF 50+ PA++++ | 68% | $32.40 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Homosalate, Ethylhexyl methoxycinnamate, Ethylhexyl salicylate, Zinc oxide, Water, Caprylic/capric triglyceride, Silica, Squalane, Glycerin, Niacinamide, Dimethicone, Glyceryl stearate, Peg-100 stearate, Cetearyl alcohol, Butyrospermum parkii butter, Polygonum aviculare extract, Physalis angulata extract, Dunaliella salina extract, Ubiquinone, Camellia sinensis leaf extract, Tremella fuciformis sporocarp extract, Betaine, Melanin, Tocopheryl acetate, Tocopherol, Hydroxyacetophenone, Batyl alcohol, C12-15 alkyl benzoate, Panthenol, Butylene glycol, Ceteareth-20, Polyhydroxystearic acid, Isostearic acid, Xanthan gum, Ethylhexylglycerin, Disodium edta, Aminomethyl propanol, Caprylyl glycol, Potassium sorbate, Sorbic acid, Phenoxyethanol
- Opinion on Homosalate - Scientific Committee on Consumer Products
- A review of inorganic UV filters zinc oxide and titanium dioxide
- Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens
- Characterization of the UVA protection provided by avobenzone, zinc oxide, and titanium dioxide in broad-spectrum sunscreen products
- Ultraviolet Protection Properties of Commercial Sunscreens and Sunscreens Containing Zno Nanorods
- ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Juglanin ameliorates UVB-induced skin carcinogenesis via anti-inflammatory and proapoptotic effects in vivo and in vitro
- Dunaliella salina alga extract inhibits the production of interleukin-6, nitric oxide, and reactive oxygen species by regulating nuclear factor-κB/Janus kinase/signal transducer and activator of transcription in virus-infected RAW264.7 cells
- Biochemical composition and bioactivity screening of various extracts from Dunaliella salina, a green microalga
- Carboxymethylation of polysaccharides from Tremella fuciformis for antioxidant and moisture-preserving activities
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics