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SkinCeuticals Tripeptide-R Neck Repair
SkinCeuticals

SkinCeuticals Tripeptide-R Neck Repair

Efficacy91/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Retinol, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate + 2 more
Works well
What the product description says
“Corrective retinol neck treatment targets early to advanced signs of visible neck aging”
Source: Skinceuticals

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%
Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetateKey activeEffect: MediumA peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid~0.2–0.35%
Magnesium aluminum silicateEffect: LowMight be helpful in restoring skin barrier function and, when combined with zinc carbonate and malonic acid, reducing fine lines and wrinkles by stimulating elastin production. Also helps stabilize the product formulation~0.25–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%
Evens skin tone
Retinol
Works well
What the product description says
“Clinically demonstrated to improve the appearance of visible neck aging, including horizontal neck lines and wrinkles, loss of firmness, crepiness, and uneven skin tone”
Source: Skinceuticals

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%
Moisturizing
Glycerin, Dimethicone + 13 more
Works
What the product description says
“This powerful and targeted cream combines tri-functional technology with a hydrating delivery system.”
Source: Face the Future

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hydrolyzed rice protein.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, myristyl myristate.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~5.7–6.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.7–5.8%
Helianthus annuus seed oil unsaponifiablesKey active· EmollientEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~1.6–2%
Myristyl myristateKey active· Emollient, OcclusiveEffect: HighAn emollient. Is not recommended for acne-prone skin as it can be comedogenic~1.4–1.8%
Capryloyl glycineKey activeEffect: MediumHelps oil and water mix together, preserve cosmetic products, and attract water to the upper layer of the skin~0.6–0.9%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~0.55–0.8%
Hydrolyzed rice proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~0.3–0.55%
Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetateKey activeEffect: HighA peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid~0.2–0.35%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~3.4–4.2%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.5–0.75%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.5–0.75%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.35–0.6%
BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.1–0.15%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.55–0.8%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%
Anti-oxidation
Side benefit · Retinol, Hydrolyzed rice protein + 2 more
Works well

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%
Hydrolyzed rice proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~0.3–0.55%
Rosmarinus officinalis leaf oilEffect: Low, below effective doseA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin~0.25–0.4%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%
Exfoliation
Side benefit · Retinol
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%
Anti-blemish
Side benefit · Retinol
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.45%

Can it cause trouble?

Irritancy
6 strong irritants: Retinol, Alcohol + 4 more — patch-test recommended
High risk
We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.25–0.45%est.
Coco-glucosideUsed as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritatingHigh~0.3–0.55%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.25–0.45%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.25–0.45%est.
Rosmarinus officinalis leaf oilA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skinHigh~0.25–0.4%est.
Mentha piperita oilUsed as a fragrance and can be irritatingHigh~0.2–0.4%est.
LinaloolA fragrance. Can be irritatingHigh~0.2–0.35%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenicMedium~1.4–1.8%est.
Allyl methacrylates crosspolymerUsed to stabilize product formulationsMedium~1.1–1.3%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.6–0.95%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.5–0.75%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.5–0.75%est.
BhtA preservativeMedium~0.25–0.4%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.25–0.45%est.
Myristic acidHelps oil and water mix together. Could be comedogenicMedium~0.3–0.5%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.
Propyl gallateHelps preserve product formulations and can mask the smell of other ingredients in a productMedium~0.15–0.25%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenic3/5~1.4–1.8%est.
Myristic acidHelps oil and water mix together. Could be comedogenic3/5~0.3–0.5%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~0.55–0.8%est.
Alternatives
Cheaper, or higher on efficacy
Super Retinol Ceramide-Boost Anti-aging Face Serum
Beauty Pie Super Retinol Ceramide-Boost Anti-aging Face Serum
CheaperHigher efficacy · 100/10085% match
$55.00
Beauty Ageless Throat & Decolletage Night Crème with Retinol
PRAI Beauty Ageless Throat & Decolletage Night Crème with Retinol
Cheaper83% match
$49.22
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~5.7–6.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~4.7–5.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Hydrogenated polyisobutene~3.4–4.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Vinyl dimethicone/methicone silsesquioxane crosspolymer~2.5–3%
Formula
Irritation risk
Low

A type of silicone that create a smooth product finish and can create an optical soft-focus effect on the skin. Helps to thicken the product consistency

More about Vinyl dimethicone/methicone silsesquioxane crosspolymer
Methyl methacrylate crosspolymer~2.1–2.6%
Formula
Irritation risk
Low
Works for
Mattifying

Helps thicken the product consistency

More about Methyl methacrylate crosspolymer
Ammonium polyacryloyldimethyl taurate~1.8–2.1%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Ammonium polyacryloyldimethyl taurate
Helianthus annuus seed oil unsaponifiables~1.6–2%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil unsaponifiables
Myristyl myristate~1.4–1.8%
Key activeComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

An emollient. Is not recommended for acne-prone skin as it can be comedogenic

More about Myristyl myristate
Allyl methacrylates crosspolymer~1.1–1.3%
Irritant · medium
Irritation risk
Medium

Used to stabilize product formulations

More about Allyl methacrylates crosspolymer
Sodium hydroxide~0.75–1.1%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Potassium cetyl phosphate~0.6–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Glyceryl stearate se~0.55–0.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Capryloyl glycine~0.6–0.9%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together, preserve cosmetic products, and attract water to the upper layer of the skin

More about Capryloyl glycine
Caprylyl glycol~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Silica silylate~0.5–0.75%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Silica silylate
Pentylene glycol~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Stearic acid~0.55–0.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Hydrolyzed rice protein~0.3–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Helps attract water to the upper layer of the skin. Might have some anti-oxidant properties

More about Hydrolyzed rice protein
Palmitic acid~0.35–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Retinol~0.25–0.45%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
MattifyingAnti-agingAnti-oxidationExfoliationAnti-blemishEvens skin tone

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Polysorbate 20~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Coco-glucoside~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Cleansing

Used as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating

More about Coco-glucoside
Magnesium aluminum silicate~0.25–0.45%
Formula
Irritation risk
Low
Works for
Anti-aging

Might be helpful in restoring skin barrier function and, when combined with zinc carbonate and malonic acid, reducing fine lines and wrinkles by stimulating elastin production. Also helps stabilize the product formulation

More about Magnesium aluminum silicate
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Alcohol~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Bht~0.25–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Sodium citrate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Myristic acid~0.3–0.5%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Cleansing

Helps oil and water mix together. Could be comedogenic

More about Myristic acid
Lavandula angustifolia oil~0.25–0.45%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Rosmarinus officinalis leaf oil~0.25–0.4%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-oxidation

A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin

More about Rosmarinus officinalis leaf oil
Mentha piperita oil~0.2–0.4%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha piperita oil
Glaucine~0.2–0.4%
Formula
Irritation risk
Low
More about Glaucine
Citric acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Linalool~0.2–0.35%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate~0.2–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid

More about Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate
Magnesium chloride~0.15–0.3%
Formula
Irritation risk
Low

Helps thicken the product formulation

More about Magnesium chloride
Tocopherol~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Propyl gallate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

Helps preserve product formulations and can mask the smell of other ingredients in a product

More about Propyl gallate
Biotin~0.1–0.15%
Formula
Irritation risk
Low
Works for
Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin
Ingredient list view

Water, Glycerin, Dimethicone, Hydrogenated polyisobutene, Vinyl dimethicone/methicone silsesquioxane crosspolymer, Methyl methacrylate crosspolymer, Ammonium polyacryloyldimethyl taurate, Helianthus annuus seed oil unsaponifiables, Myristyl myristate, Allyl methacrylates crosspolymer, Sodium hydroxide, Potassium cetyl phosphate, Glyceryl stearate se, Capryloyl glycine, Caprylyl glycol, Silica silylate, Pentylene glycol, Stearic acid, Hydrolyzed rice protein, Palmitic acid, Retinol, Polysorbate 20, Coco-glucoside, Magnesium aluminum silicate, Xanthan gum, Alcohol, Bht, Sodium citrate, Myristic acid, Lavandula angustifolia oil, Rosmarinus officinalis leaf oil, Mentha piperita oil, Glaucine, Citric acid, Linalool, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, Magnesium chloride, Tocopherol, Propyl gallate, Biotin

Compare prices

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Skinceuticals
$126.00
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Bluemercury
$135.00
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Dermstore1.7 fl. oz
$136.00
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Face the Future
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Amazon US
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
SkinCeuticalsTripeptide-R Neck RepairYOUR PRODUCTBeauty PieSuper Retinol Ceramide-Boost Anti-aging Face SerumPRAIBeauty Ageless Throat & Decolletage Night Crème with RetinolStriVectinAR Eye Serum
Match—85%83%81%
Price$126.00$55.00−$71.00$49.22−$76.78$90.14−$35.86
Shared key ingredients—3 of 73 of 73 of 7
Key difference—Lactic AcidCaprylic/Capric TriglycerideDipeptide-2
Irritancy High Medium High Medium
Drying alcohol Contains drying alcohol ———
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 24 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
  5. 5
    Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmeticscir-safety.org
  6. 6
    Safety Assessment of Cross-Linked Alkyl Acrylates as Used in Cosmeticsjournals.sagepub.com
SkinCeuticals Tripeptide-R Neck Repair
SkinCeuticalsTripeptide-R Neck Repair
Buy at Skinceuticals$126.00Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Skinceuticals$126.00Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.