Skin Script

Skin Script Peptide Eye Serum

Name: Skin Script - Peptide Eye Serum
Brand: Skin Script

Efficacy83/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 + 10 more

Works well

What the product description says

“Encourages proper moisture levels”

Source: Skin Script

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glucose.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, dipeptide-2, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.65–0.95%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.55–0.85%

Dipeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.6%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

GlycosaminoglycansKey active· EmollientEffect: HighLong sugars that help attract water to the upper layer of the skin~4.3–5.2%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.4–3%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.7–2.1%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.25–0.5%

Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.2–0.35%

Tartaric acidKey activeEffect: MediumAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels~0.2–0.4%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.55%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.2–0.4%

Evens skin tone

Chrysin, N-hydroxysuccinimide + 2 more

May help

What the product description says

“It brightens the appearance of discolorations, reduces the appearance of wrinkles, stimulates circulation, and improves tissue strength while encouraging healthy cellular skin functions.”

Source: Skin Script

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: chrysin.

ChrysinKey activeEffect: MediumMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.45–0.7%

N-hydroxysuccinimideEffect: LowIs claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating~0.4–0.6%

Magnesium ascorbyl phosphateEffect: Low, below effective doseA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high~0.25–0.45%

Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~3.2–3.9%

Anti-aging

Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 + 6 more

May help

What the product description says

“The Peptide Eye Serum opens the eye zone for a refreshed, youthful appearance.”

Source: Skin Script

This product contains acetyl hexapeptide-8, astaxanthin, dipeptide-2, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1. There is some human evidence that these ingredients help reduce and prevent fine lines and wrinkles and improve skin elasticity and firmness, though it is smaller or less consistent than the evidence for the best anti-aging ingredients.

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.65–0.95%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.55–0.85%

Dipeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.6%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

AstaxanthinKey activeEffect: MediumHelps neutralize free radicals in skin and might help to calm down inflammation~0.3–0.55%

ChrysinEffect: LowMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.45–0.7%

Anti-oxidation

Side benefit · Chrysin, Astaxanthin + 5 more

Works well

This product contains antioxidants (astaxanthin) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - chrysin, tartaric acid also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

AstaxanthinKey activeEffect: HighHelps neutralize free radicals in skin and might help to calm down inflammation~0.3–0.55%

CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~1.2–1.4%

Hesperidin methyl chalconeEffect: LowMight help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation~0.25–0.45%

Can it cause trouble?

Irritancy

4 strong irritants: Hamamelis virginiana water, Alcohol + 2 more — patch-test recommended

High risk

We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Hamamelis virginiana waterA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~5.7–7%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~3.2–3.9%est.

AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~1.9–2.4%est.

Citrus limon peel oilA highly irritating fragranceHigh~0.45–0.7%est.

Citrus aurantium amara flower oilUsed as a fragrance. Can be irritatingHigh~0.45–0.65%est.

N-hydroxysuccinimideIs claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritatingHigh~0.4–0.6%est.

Hesperidin methyl chalconeMight help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritationHigh~0.25–0.45%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~1.2–1.4%est.

ChrysinMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skinMedium~0.45–0.7%est.

AstaxanthinHelps neutralize free radicals in skin and might help to calm down inflammationMedium~0.3–0.55%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.55%est.

Magnesium ascorbyl phosphateA derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very highMedium~0.25–0.45%est.

Steareth-20Helps oil and water mix togetherMedium~0.3–0.55%est.

Tartaric acidAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levelsMedium~0.2–0.4%est.

Acetyl tributyl citrateUsed to create a thicker product consistencyMedium~0.15–0.3%est.

Phytic acidAn alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmeticsMedium~0.1–0.2%est.

Potassium sorbateA preservativeMedium~0.1–0.2%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.2–0.35%est.

Alternatives

Cheaper, or higher on efficacy

Kiehl's Powerful-Strength Dark Circle Reducing Vitamin C Eye Serum

Higher efficacy · 100/10080% match

$49.73

Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%

Higher efficacy · 100/10079% match

$44.00

View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Hamamelis virginiana water~5.7–7%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana water

Glycosaminoglycans~4.3–5.2%

Key active

Irritation risk: Low

Works for

Moisturizing

Long sugars that help attract water to the upper layer of the skin

More about Glycosaminoglycans

Ascorbic acid~3.2–3.9%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-oxidationEvens skin toneAnti-aging

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Glycerin~2.4–3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Alcohol~1.9–2.4%

Irritant · high

Irritation risk: High

Works for

Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol

Squalane~1.7–2.1%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Polysorbate 20~1.5–1.8%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Caffeine~1.2–1.4%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Ppg-3 benzyl ether myristate~1.2–1.4%

Formula

Irritation risk: Low

More about Ppg-3 benzyl ether myristate

Phenyl t-butylnitrone~0.7–1.1%

Formula

Irritation risk: Low

More about Phenyl t-butylnitrone

Palmitoyl tripeptide-1~0.65–0.95%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7~0.55–0.85%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Citrus limon peel oil~0.45–0.7%

Irritant · high

Irritation risk: High

A highly irritating fragrance

More about Citrus limon peel oil

Chrysin~0.45–0.7%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-oxidationAnti-aging

Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin

More about Chrysin

Citrus aurantium amara flower oil~0.45–0.65%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Citrus aurantium amara flower oil

N-hydroxysuccinimide~0.4–0.6%

Irritant · high

Irritation risk: High

Works for

Evens skin tone

Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating

More about N-hydroxysuccinimide

Dipeptide-2~0.35–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide-2

Astaxanthin~0.3–0.55%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-agingAnti-inflammatory

Helps neutralize free radicals in skin and might help to calm down inflammation

More about Astaxanthin

Acetyl hexapeptide-8~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Caprylyl glycol~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Glucose~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Magnesium ascorbyl phosphate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-agingEvens skin toneAnti-oxidation

A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high

More about Magnesium ascorbyl phosphate

Hesperidin methyl chalcone~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Might help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation

More about Hesperidin methyl chalcone

Steareth-20~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Steareth-20

Butylene glycol~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Tartaric acid~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

ExfoliationAnti-oxidationMoisturizing

An AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels

More about Tartaric acid

Acetyl tributyl citrate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Used to create a thicker product consistency

More about Acetyl tributyl citrate

Chondrus crispus extract~0.2–0.35%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract

Xanthan gum~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Carbomer~0.15–0.25%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Phytic acid~0.1–0.2%

Irritant · medium

Irritation risk: Medium

An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics

More about Phytic acid

Phenoxyethanol~0.1–0.25%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Potassium sorbate~0.1–0.2%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Ingredient list view

Water, Hamamelis virginiana water, Glycosaminoglycans, Ascorbic acid, Glycerin, Alcohol, Squalane, Polysorbate 20, Caffeine, Ppg-3 benzyl ether myristate, Phenyl t-butylnitrone, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Citrus limon peel oil, Chrysin, Citrus aurantium amara flower oil, N-hydroxysuccinimide, Dipeptide-2, Astaxanthin, Acetyl hexapeptide-8, Caprylyl glycol, Glucose, Magnesium ascorbyl phosphate, Hesperidin methyl chalcone, Steareth-20, Butylene glycol, Tartaric acid, Acetyl tributyl citrate, Chondrus crispus extract, Xanthan gum, Carbomer, Phytic acid, Phenoxyethanol, Potassium sorbate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Skin ScriptPeptide Eye SerumYOUR PRODUCT	Kiehl'sPowerful-Strength Dark Circle Reducing Vitamin C Eye Serum	CliniqueFresh Pressed Daily Booster with Pure Vitamin C 10%	REVOLUTION SKINCARERevolution Man Anti-Fatigue Under Eye Serum
Match	—	80%	79%	79%
Price	—	$49.73	$44.00	—
Shared key ingredients	—	5 of 13	7 of 13	4 of 13
Key difference	—	Adenosine	Salicylic Acid	Titanium Dioxide
Irritancy	High	Low	Medium	Low
Drying alcohol	Contains drying alcohol	—	—	—
	View product	Shop	Shop	Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 20 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Anti-photoageing and anti-melanogenesis activities of chrysinncbi.nlm.nih.gov
3
Chrysin Protects Epidermal Keratinocytes from UVA- and UVB-Induced Damagepubs.acs.org
4
Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activitysciencedirect.com
5
Biological Activities and Safety of Citrus spp. Essential Oilsncbi.nlm.nih.gov
6
Astaxanthin, canthaxanthin and b-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymesonlinelibrary.wiley.com
7
Astaxanthin attenuates the UVA-induced up-regulation of matrixmetalloproteinase-1 and skin fibroblast elastase in human dermal fibroblastssciencedirect.com
8
Protective Effects of Topical Application of a Poorly Soluble Antioxidant Astaxanthin Liposomal Formulation on Ultraviolet-Induced Skin Damageonlinelibrary.wiley.com
9
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Functionncbi.nlm.nih.gov
10
Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivativesncbi.nlm.nih.gov
11
Topical L-ascorbic acid: percutaneous absorption studiesncbi.nlm.nih.gov
12
Hesperidin methyl chalcone - a new cosmetic contact allergenncbi.nlm.nih.gov
13
Benefits of Hesperidin for Cutaneous Functionshindawi.com
14
Control of keratinization with á-hydroxy acids and related compounds: I. Topical treatment of ichthyotic disordersjamanetwork.com
15
Dual Effects of Alpha-Hydroxy Acids on the Skinmdpi.com
16
Method of treating wrinkles using tartaric acidpatents.google.com
17
Impact of the condition of storage of tartaric acid solutions on the production and stability of glyoxylic acidsciencedirect.com
18
Final report on the safety assessment of acetyl triethyl citrate, acetyl tributyl citrate, acetyl trihexyl citrate, and acetyl trioctyl citratencbi.nlm.nih.gov
19
Cosmetic and dermatologic use of alpha hydroxy acidsonlinelibrary.wiley.com
20
Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasmancbi.nlm.nih.gov

Skin ScriptPeptide Eye Serum

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