PRODUCT REVIEW
Sesderma SESRETINAL Mature Skin Liposomal Serum
Added by claudia5236
Add to Compare
Cheaper alternatives
What can the product work for?
Anti-aging
glycolic acid
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
retinal
0.3% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Show more
Anti-blemish
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
retinal
0.3% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
glycolic acid
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Show more
Evens skin tone
glycolic acid
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
mandelic acid
0.25% -
0.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid
Show more
Exfoliation
mandelic acid
0.25% -
0.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid
glycolic acid
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
gluconolactone
0.15% -
0.3%
Irritation risk:
Concentration: Insufficient!
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Show more
Moisturizing
Irritation risk:
Concentration: Effectiveness: HIGH
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
sodium hyaluronate
0.3% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
glucosamine hcl
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
Show more
Anti-oxidation
glycyrrhetinic acid
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
glucosamine hcl
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness:
LOW
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
Show more
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging |
Total Promises Fulfilled score:
100/100.
Buy now
We receive a small commission for purchases made through these links at no cost for you. Thank you for your support! Learn more
Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 2
Potential irritants
alcohol
0.55% -
0.8%
Irritation risk:
Works for:
Antibacterial
Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
retinal
0.3% -
0.55%
Irritation risk:
Works for:
Anti-aging,
Anti-blemish,
Evens skin tone
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Show more
Comodogenic ingredients
cetearyl alcohol
0.25% -
0.45%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
gossypium herbaceum seed oil
0.2% -
0.35%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Cottonseed oil. It is used as an emollient and occlusive in products. It is rich palmitic, oleic acid, and linoleic fatty acids.
User reviews (0)
Similar products & dupes
| Sesderma - SESRETINAL Mature Skin Liposomal Serum |  skinmade - Tranexamic acid + Retinal serum |  Ao Skincare - Reverse Longitude PM Serum-Shot |  Dr Dennis Gross - Advanced Retinol + Ferulic Texture Renewal Serum Packette |  Lancer - Younger: Pure Youth Serum |  Lancer Skincare - Younger: Pure Youth Serum |  Dermadoctor - Calm Cool + Corrected Bakuchiol Retinol Alternative Serum |  Live Tinted - Superhue Hyperpigmentation Serum Stick |  Naturium - Retinol Serum 2.5% |  Lise Watier - Sublimessence High Firming Lifting Serum |  Noble Panacea - The Brilliant Prime Radiance Serum | |
| Price | |||||||||||
| WIMJ similarity score |
70%
|
68%
|
57%
|
57%
|
57%
|
55%
|
55%
|
52%
|
51%
|
51%
| |
| Key ingredients | Common:
Other: | Common:
Other: | Common:
Other:
| Common:
Other:
| Common:
Other:
| Common:
Other: | Common:
Other: | Common:
Other: | Common:
Other: | Common:
Other:
| |
| Irritancy | IRRITANCY
HIGH
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
HIGH
| IRRITANCY
HIGH
|
| Potential Irritants |
|
|
|
|
|
|
|
|
|
|
|
| All ingredients |
|
|
|
|
|
|
|
|
|
|
|
Ingredients & concentrations
All ingredients
Key Actives
gluconolactone
0.15% -
0.3%
Irritation risk:
Works for:
Evens skin tone,
Exfoliation,
Moisturizing,
Anti-aging,
Anti-blemish,
Anti-oxidation
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
glucosamine hcl
0.2% -
0.35%
Irritation risk:
Works for:
Antibacterial,
Moisturizing,
Evens skin tone,
Anti-oxidation,
Anti-aging
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
Show more
Potential irritants
alcohol
0.55% -
0.8%
Irritation risk:
Works for:
Antibacterial
Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
retinal
0.3% -
0.55%
Irritation risk:
Works for:
Anti-aging,
Anti-blemish,
Evens skin tone
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Show more
Comodogenic ingredients
cetearyl alcohol
0.25% -
0.45%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
gossypium herbaceum seed oil
0.2% -
0.35%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Cottonseed oil. It is used as an emollient and occlusive in products. It is rich palmitic, oleic acid, and linoleic fatty acids.
All ingredients
bis-peg-18 methyl ether dimethyl silane
5.2% -
6.4%
Irritation risk:
Works for:
Cleansing,
Moisturizing
A type of silicone that helps soften the upper layer of the skin and create a nice product texture
hydrogenated polydecene
3.9% -
4.8%
Irritation risk:
Works for:
Moisturizing
Helps to soften the upper layer of the skin and create a nice product texture
Show more
Ingredient list view
Water, Bis-peg-18 methyl ether dimethyl silane, Hydrogenated polydecene, C12-15 alkyl benzoate, Ceteth-20, Propanediol, Glycerin, Glyceryl stearate, Cyclopentasiloxane, Triethanolamine, Alcohol, Potassium cetyl phosphate, Zinc chloride, Sodium hyaluronate, Retinal, Nicotiana benthamiana sh-polypedtide-7, Niacin, Mandelic acid, Lycium barbarum fruit extract, Glycyrrhetinic acid, Glycolic acid, Glucosamine hcl, Bidens pilosa extract, Bakuchiol, Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40, Nicotiana benthamiana hexapeptide-40 sh-polypeptide-5, Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1, Gluconolactone, Lecithin, Cyclohexasiloxane, Tocopheryl acetate, Titanium dioxide, Cetearyl alcohol, Titanium dioxide, Xanthan gum, Polysorbate 20, Polyglyceryl-3 polyricinoleate, Disodium edta, Sodium cholate, Sodium chloride, Stearic acid, Silica, Aminopropyl triethoxysilane, Tocopherol, Ascorbyl palmitate, Ammonium acryloyldimethyltaurate/vp copolymer, Dipotassium phosphate, Sodium hydroxide, Glyceryl oleate, Tromethamine, Citric acid, Hydrochloric acid, Potassium phosphate, Retinyl palmitate, Elaeis guineensis oil, Gossypium herbaceum seed oil, Linum usitatissimum seed oil, Lactic acid, Phenoxyethanol, Ethylhexylglycerin, Sodium benzoate, Potassium sorbate, Parfum
Sources
- Safety Assessment of Polyene Group as Used in Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Summary of mandelic acid for the improvement of skin conditions
- Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma
- Water-soluble polysaccharide from dried Lycium barbarum fruits: Isolation, structural features and antioxidant activity
- Lycium barbarum polysaccharide protects human keratinocytes against UVB-induced photo-damage
- Lycium Barbarum and Human Health
- Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application
- Effects of topical application of B‐Resorcinol and Glycyrrhetinic acid monotherapy and in combination with fractional CO2 laser treatment for benign hand hyperpigmentation treatment
- 18β-Glycyrrhetinic Acid and Glabridin Prevent Oxidative DNA Fragmentation in UVB-irradiated Human Keratinocyte Cultures
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Glucosamine: an ingredient with skin and other benefits
- Bakuchiol in the Management of Acne-affected Skin
- Prospective, randomized, double‐blind assessment of topical bakuchiol and retinol for facial photoageing
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids
- Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Light
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Contact Sensitization to Emulsifying Agents: An Underrated Issue?
- Safety Assessment of Tromethamine as Used in Cosmetics
- Genetic Architecture of Palm Oil Fatty Acid Composition in Cultivated Oil Palm (Elaeis guineensis Jacq.) Compared to Its Wild Relative E. oleifera (H.B.K) Cortés
- Nutrient composition of Nigerian palm kernel from the dura and tenera varieties of the oil palm (Elaeis guineensis)
- Epidermal and dermal effects of topical lactic acid