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Product summary

"Sesderma - Retises 0.25% Anti-Wrinkle Regenerating Cream" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Sesderma - Retises 0.25% Anti-Wrinkle Regenerating Cream ticks this box. Peg-8, propylene glycol and glyceryl polymethacrylate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (caprylic/capric triglyceride, dimethicone, helianthus annuus seed oil, c12-15 alkyl benzoate and cetyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • this moisturizer contains an effective form of Retinoids (vitamin A): retinol 0.20% - 0.35%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of Retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternate days or when your skin feels dry.
  • This moisturizer also contains Peptides (palmitoyl oligopeptide 0.30% - 0.55%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, salicylic acid and lecithin

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 36.00£ in the United Kingdom.

For a detailed price comparison: click here.