Radical Skincare Extreme Repair

Radical Skincare Extreme Repair

Efficacy83/100IrritancyHigh
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Works for

2 of 3 advertised claims delivered

Anti-aging
Adenosine, Acetyl hexapeptide-8 + 6 more
Strong evidence
What the product description says
“Age-Defying Benefits – Reduces the appearance of fine lines and wrinkles, evens skin tone, and softens skin for a youthful glow.”
Source: Radical Skincare

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.35%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.5–1.8%
NiacinamideUnder-dosedEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.2–0.35%
Ascorbyl tetraisopalmitateUnder-dosedEffect: MediumA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Moisturizing
Acetyl hexapeptide-8, Palmitoyl tripeptide-5 + 30 more
Strong evidence
What the product description says
“Treat your skin to the intensely hydrating properties of Radical Skincare Extreme Repair, a rich, deeply nourishing face cream that is unbleached to retain its natural colour.”
Source: Lookfantastic

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: anhydroxylitol, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tripeptide-5

Copernicia cerifera waxKey active· Emollient, OcclusiveEffect: HighHelps to soften the upper layer of the skin and create a nice product consistency~0.3–0.6%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.2–1.5%
Oryza sativa bran oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and might have some anti-oxidant properties~0.5–0.75%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.1–0.2%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.4%
Vaccinium macrocarpon seed oilKey active· EmollientEffect: HighA plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier function~0.2–0.4%
XylitylglucosideKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrier function~0.9–1.1%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
AnhydroxylitolKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrir function~0.45–0.65%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.8–5.8%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.5–1.8%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.4–2.9%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%
Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.25–0.4%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.25–0.45%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.6–2%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.35%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~3.8–4.6%
GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.2–0.35%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.45–0.7%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~2–2.4%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.25–0.45%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.4%
Balanites roxburghii seed oilEffect: LowAn emollient. Could be irritating~0.65–0.95%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.25%
NiacinamideUnder-dosedEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.2–0.35%
Ascorbyl tetraisopalmitateEffect: Low, below effective doseA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.2–0.4%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.5–0.75%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Evens skin tone
Hexylresorcinol, Camellia sinensis leaf extract + 2 more
Limited evidence
What the product description says
“Nourishing and brightening the look of dry skin, the reparative cream targets areas of discolouration and utilises three lightening and brightening agents to promote radiant, more even toned complexion.”
Source: Lookfantastic

This product contains ingredients (hexylresorcinol) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.

HexylresorcinolEffect: LowMight be helpful in reducing hyperpigmentation and neutralizing free radicals in skin~0.25–0.45%
NiacinamideUnder-dosedEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.2–0.35%
Ascorbyl tetraisopalmitateUnder-dosedEffect: MediumA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.2–0.4%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Anti-oxidation
Not advertised by the brand · Superoxide dismutase, Hexylresorcinol + 9 more
Strong evidence

This product contains antioxidants (superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - hexylresorcinol, vaccinium macrocarpon seed oil also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.1–0.2%
HexylresorcinolKey activeEffect: MediumMight be helpful in reducing hyperpigmentation and neutralizing free radicals in skin~0.25–0.45%
Vaccinium macrocarpon seed oilKey activeEffect: MediumA plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier function~0.2–0.4%
Coffea arabica seed extractEffect: LowMight be helpful in neutralizing free radicals in skin~0.1–0.15%
Euterpe oleracea fruit extractEffect: LowA plant extract that can have some anti-oxidant effect in skin~0.2–0.4%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.35%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.5–1.8%
Ascorbyl tetraisopalmitateUnder-dosedEffect: HighA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.2–0.4%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.15–0.3%

Can it cause trouble?

Irritancy
6 strong irritants: Balanites roxburghii seed oil, Limonene + 4 more — patch-test recommended
High risk
We flagged 21 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Balanites roxburghii seed oilAn emollient. Could be irritatingHigh~0.65–0.95%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.35%est.
Citrus aurantium dulcis peel oilAn essentil oil from orange peel. Potential allergen and can be irritatingHigh~0.2–0.35%est.
Citrus tangerina peel oilEssential oil that can be irritating. Can lead to photosensitivityHigh~0.2–0.35%est.
Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.25–0.5%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.15–0.3%est.
LinaloolA fragrance. Can be irritatingHigh~0.15–0.25%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.4–2.9%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.3–0.6%est.
HexylresorcinolMight be helpful in reducing hyperpigmentation and neutralizing free radicals in skinMedium~0.25–0.45%est.
Vaccinium macrocarpon seed oilA plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier functionMedium~0.2–0.4%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.2–0.4%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.35%est.
O-cymen-5-olA preservativeMedium~0.05–0.1%est.
Euterpe oleracea fruit extractA plant extract that can have some anti-oxidant effect in skinMedium~0.2–0.4%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.25–0.45%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.25–0.4%est.
Sodium dehydroacetateA preservativeMedium~0.2–0.35%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.4%est.
Ascorbyl tetraisopalmitateA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)Medium~0.2–0.4%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.5–1.8%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~3.8–4.6%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.8–5.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glyceryl stearate se~3.8–4.6%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Propanediol~3–3.7%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Caprylic/capric triglyceride~2.4–2.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Isononyl isononanoate~2–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Cetyl alcohol~1.6–2%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Butyrospermum parkii butter~1.5–1.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Dimethicone~1.2–1.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Xylitylglucoside~0.9–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitylglucoside
Balanites roxburghii seed oil~0.65–0.95%
Irritant · high
Irritation risk
High
Works for
AntibacterialMoisturizing

An emollient. Could be irritating

More about Balanites roxburghii seed oil
Methyl methacrylate crosspolymer~0.6–0.9%
Formula
Irritation risk
Low
Works for
Mattifying

Helps thicken the product consistency

More about Methyl methacrylate crosspolymer
Oryza sativa bran oil~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and might have some anti-oxidant properties

More about Oryza sativa bran oil
Anhydroxylitol~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrir function

More about Anhydroxylitol
Phenoxyethanol~0.4–0.6%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Palmitic acid~0.45–0.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Stearic acid~0.5–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Tromethamine~0.3–0.6%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Potassium cetyl phosphate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Carbomer~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Hexylresorcinol~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin

More about Hexylresorcinol
Sodium pca~0.25–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca
Vaccinium macrocarpon seed oil~0.2–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier function

More about Vaccinium macrocarpon seed oil
Copernicia cerifera wax~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and create a nice product consistency

More about Copernicia cerifera wax
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Xylitol~0.2–0.35%
Formula
Irritation risk
Low

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitol
Oryza sativa hull powder~0.25–0.5%
Formula
Limonene~0.2–0.35%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Squalane~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Disodium edta~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Citrus aurantium dulcis peel oil~0.2–0.35%
Irritant · high
Irritation risk
High

An essentil oil from orange peel. Potential allergen and can be irritating

More about Citrus aurantium dulcis peel oil
Citrus tangerina peel oil~0.2–0.35%
Irritant · high
Irritation risk
High

Essential oil that can be irritating. Can lead to photosensitivity

More about Citrus tangerina peel oil
O-cymen-5-ol~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about O-cymen-5-ol
Euterpe oleracea fruit extract~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can have some anti-oxidant effect in skin

More about Euterpe oleracea fruit extract
Pentylene glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Decyl glucoside~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside
Glucose~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose
Polysorbate 60~0.25–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Sodium dehydroacetate~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sodium dehydroacetate
Tocopherol~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Adenosine~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Helianthus annuus seed oil~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Rosmarinus officinalis leaf extract~0.15–0.3%
Irritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Caprylyl glycol~0.25–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sodium hyaluronate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Lecithin~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Sorbitan isostearate~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Ascorbyl tetraisopalmitate~0.2–0.4%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin toneAnti-agingMoisturizing

A vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)

More about Ascorbyl tetraisopalmitate
Niacinamide~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Palmitoyl tripeptide-5~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Phaeodactylum tricornutum extract~0.15–0.3%
Formula
Allantoin~0.15–0.25%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-blemishReduces irritationReduces rednessExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Xanthan gum~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Acetyl hexapeptide-8~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Linalool~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Camellia sinensis leaf extract~0.15–0.25%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingMoisturizingAnti-blemishEvens skin tone

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Coffea arabica seed extract~0.1–0.15%
Formula
Irritation risk
Low
Works for
Anti-oxidation

Might be helpful in neutralizing free radicals in skin

More about Coffea arabica seed extract
Superoxide dismutase~0.1–0.2%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatory

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase
Ingredient list view

Water, Glycerin, Glyceryl stearate se, Propanediol, Caprylic/capric triglyceride, Isononyl isononanoate, Cetyl alcohol, Butyrospermum parkii butter, Dimethicone, Xylitylglucoside, Balanites roxburghii seed oil, Methyl methacrylate crosspolymer, Oryza sativa bran oil, Anhydroxylitol, Phenoxyethanol, Palmitic acid, Stearic acid, Tromethamine, Potassium cetyl phosphate, Carbomer, Hexylresorcinol, Sodium pca, Vaccinium macrocarpon seed oil, Copernicia cerifera wax, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Xylitol, Oryza sativa hull powder, Limonene, Squalane, Chlorphenesin, Disodium edta, Citrus aurantium dulcis peel oil, Citrus tangerina peel oil, O-cymen-5-ol, Euterpe oleracea fruit extract, Pentylene glycol, Decyl glucoside, Glucose, Polysorbate 60, Sodium dehydroacetate, Tocopherol, Adenosine, Helianthus annuus seed oil, Rosmarinus officinalis leaf extract, Caprylyl glycol, Sodium hyaluronate, Lecithin, Sorbitan isostearate, Ascorbyl tetraisopalmitate, Niacinamide, Palmitoyl tripeptide-5, Phaeodactylum tricornutum extract, Allantoin, Xanthan gum, Acetyl hexapeptide-8, Linalool, Camellia sinensis leaf extract, Coffea arabica seed extract, Superoxide dismutase

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Amazon USPrice as of 10/22/2026 09:27 GMT
$150.00
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Radical Skincare
≈ $155.55
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Radical SkincareExtreme RepairYOUR PRODUCTNEOGEN X SUR.MEDICAgecure Intensive New Age CreamRejuranTurnover Cream Enhanced 50mlAbibYesStyle Exclusive PDRN Volume Fill-it Booster Crème 2.5 Tube Mini 5pcs Bundle Set
Match—89%85%85%
Price$134.02—$46.21−$87.81$37.53−$96.49
Shared key ingredients—14 of 2410 of 2410 of 24
Key difference—MadecassosidePentapeptide-18Copper Tripeptide-1
Irritancy High Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 42 studies and safety reviews.

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