PRODUCT REVIEW
PharmaClinix Anti Agex Serum
Buy from Amazon US $126.84
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Price as of 2/11/2023 2:22 GMT.
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What can the product work for?
Anti-aging
What does the product description say?
niacinamide
2.7% -
4%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
retinal
3.9% -
5.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
ascorbic acid
23% -
34%
Irritation risk:
Concentration: Effectiveness: HIGH
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Show more
Evens skin tone
What does the product description say?
niacinamide
2.7% -
4%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
ascorbic acid
23% -
34%
Irritation risk:
Concentration: Effectiveness: HIGH
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
retinal
3.9% -
5.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Show more
Exfoliation
What does the product description say?
salicylic acid
1.2% -
1.7%
Irritation risk:
Concentration: Effectiveness: HIGH
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
Moisturizing
What does the product description say?
helianthus annuus seed oil
0.35% -
0.85%
Irritation risk:
Concentration: Effectiveness: HIGH
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
hyaluronic acid
4.5% -
6.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
niacinamide
2.7% -
4%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Show more
Anti-blemish
retinal
3.9% -
5.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
niacinamide
2.7% -
4%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
salicylic acid
1.2% -
1.7%
Irritation risk:
Concentration: Effectiveness: HIGH
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
Anti-oxidation
ascorbyl tetraisopalmitate
5.6% -
8.4%
Irritation risk:
Concentration: Effectiveness: HIGH
A vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)
ferulic acid
0.55% -
1.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%
ascorbic acid
23% -
34%
Irritation risk:
Concentration: Effectiveness: HIGH
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Show more
Honesty check
How honest is this product?
Promise | Can it deliver? |
---|---|
Anti-aging | |
Exfoliation | |
Moisturizing | |
Evens skin tone |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 0
Potential irritants
ascorbic acid
23% -
34%
Irritation risk:
Works for:
Anti-oxidation,
Anti-aging,
Evens skin tone
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
retinal
3.9% -
5.8%
Irritation risk:
Works for:
Anti-blemish,
Anti-aging,
Evens skin tone
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Show more
Comodogenic ingredients
No comodogenic ingredients detected
User reviews (0)
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Irritancy | IRRITANCY
MEDIUM
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LOW
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LOW
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MEDIUM
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LOW
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
2.7% -
4%
Irritation risk:
Works for:
Anti-blemish,
Moisturizing,
Anti-aging,
Evens skin tone,
Reduces irritation,
Anti-inflammatory,
Reduces redness,
Antibacterial
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
salicylic acid
1.2% -
1.7%
Irritation risk:
Works for:
Exfoliation,
Anti-inflammatory,
Anti-blemish,
Antibacterial,
Evens skin tone
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
Show more
Potential irritants
ascorbic acid
23% -
34%
Irritation risk:
Works for:
Anti-oxidation,
Anti-aging,
Evens skin tone
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
retinal
3.9% -
5.8%
Irritation risk:
Works for:
Anti-blemish,
Anti-aging,
Evens skin tone
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Show more
Comodogenic ingredients
We couldn't find any comodogenic ingredients in this product
All ingredients
ascorbic acid
23% -
34%
Irritation risk:
Works for:
Anti-oxidation,
Anti-aging,
Evens skin tone
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
ascorbyl tetraisopalmitate
5.6% -
8.4%
Irritation risk:
Works for:
Anti-oxidation,
Anti-aging,
Evens skin tone,
Moisturizing
A vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)
hyaluronic acid
4.5% -
6.8%
Irritation risk:
Works for:
Moisturizing,
Anti-inflammatory,
Anti-aging
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Show more
Ingredient list view
Ascorbic acid, Ascorbyl tetraisopalmitate, Hyaluronic acid, Retinal, Niacinamide, Salicylic acid, Polypeptide-23, Tocopherol, Ferulic acid, Camellia sinensis extract, Ascorbic acid, Helianthus annuus seed oil, Citric acid
Sources
- Assessment of penetration of Ascorbyl Tetraisopalmitate into biological membranes by molecular dynamics
- Stability evaluation of tocopheryl acetate and ascorbyl tetraisopalmitate in isolation and incorporated in cosmetic formulations using thermal analysis
- A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties
- New lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), suppresses senile lentigo through controlling of melanocytes-keratinocytes interaction
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Salicylic acid as a peeling agent: a comprehensive review
- Beta Hydroxy Acids
- A review of toxicity from topical salicylic acid preparations
- Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Study
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Ferulic Acid: Therapeutic Potential Through Its Antioxidant Property
- Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin
- Antioxidant Properties of Ferulic Acid and Its Possible Application
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin