Works for:
based on ingredients and %- Anti-aging
- Evens skin tone
- Moisturizing
- Exfoliation
Can it cause trouble?
- Irritation risk: low
- Comedogenic risk ingredients: 3
Key actives
Product Summary
"Perricone MD - Neuropeptide Facial Cream" is a well-rounded moisturizing product. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (mannitol and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (dimethicone, cetearyl alcohol, elaeis guineensis oil, caprylyl glycol and glyceryl stearate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- We like that this moisturizer contains peptides (acetyl tetrapeptide-9 0.35% - 0.85%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails for 240.00$ in the United States and for 99.00£ in the United Kingdom.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
What It Does Addresses the 4-types of wrinkles.
Source: Perricone MD
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-9, tocotrienols.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Anti-oxidation
This product contains antioxidants (tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Evens skin tone
What does the product description say?
Improved appearance of skin resilience, tone and texture.
Source: Perricone MD
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Moisturizing
What does the product description say?
Neuropeptide Facial Cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
mannitol, caprylyl glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetearyl alcohol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-9
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps to attract water to the upper layer of the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Might be helpful in restoring skin barrier function and calm down inflammation in skin
Helps soften the upper layer of the skin
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps preserve products and creates a nice product texture
Helps soften the upper layer of the skin and create a thicker product consistency
Used to preserve products, dissolve other ingredients and create a nice product texture
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might be helpful in restoring skin barrier function and calm down inflammation in skin
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Helps to attract water to the upper layer of the skin
Potential irritants
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Helps soften the upper layer of the skin and create a thicker product consistency
Helps oil and water mix together. Has some emollient properties
Used to preserve products, dissolve other ingredients and create a nice product texture
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Helps preserve products and creates a nice product texture
Comedogenic ingredients
Helps soften the upper layer of the skin and create a thicker product consistency
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps oil and water mix together. Has some emollient properties
All ingredients
Helps soften the upper layer of the skin and create a thicker product consistency
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps oil and water mix together. Has some emollient properties
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix togehter and creates a nice product texture
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Used to preserve products, dissolve other ingredients and create a nice product texture
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Might be helpful in restoring skin barrier function and calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
Helps preserve products and creates a nice product texture
Ingredient list view
Water, Phosphatidylcholine, Isopropyl palmitate, Cetearyl alcohol, Tyrosine, Dimethyl mea, Ceteareth-20, Glyceryl stearate, Peg-100 stearate, Glycolic acid, Pentylene glycol, Pyruvic acid, Acetyl tetrapeptide-9, Copper gluconate, Ethylhexylglycerin, Magnesium aspartate, Zinc gluconate, Tocotrienols, Tocopherol, Mannitol, Disodium edta, Dimethicone, Propanediol, Caprylyl glycol, Elaeis guineensis oil
- Final Report on the Safety Assessment of Isopropyl Isostearate
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines
- Zinc salts in dermatology
- An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
- Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins
- Evaluation of the effects of topical zinc gluconate in wound healing
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
- Tocotrienol‐rich fraction attenuates UV‐induced inflammaging: A bench to bedside study
- Tocotrienols: Vitamin E beyond tocopherols
- Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)
- Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Genetic Architecture of Palm Oil Fatty Acid Composition in Cultivated Oil Palm (Elaeis guineensis Jacq.) Compared to Its Wild Relative E. oleifera (H.B.K) Cortés
- Nutrient composition of Nigerian palm kernel from the dura and tenera varieties of the oil palm (Elaeis guineensis)