Glytone Age-Defying Peptide+ Overnight Restorative Cream

Glytone Age-Defying Peptide+ Overnight Restorative Cream

Efficacy100/100IrritancyLow

Works for

Evens skin tone
Glycolic acid, Albizia julibrissin bark extract + 1 more
Works well
What the product description says
“Glycolic Acid works to even skin tone and texture while Hyaluronic Acid hydrates and plumps.”
Source: Dermstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: albizia julibrissin bark extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.9–7.2%
Albizia julibrissin bark extractEffect: LowA plant extract that might help to neutralize free radicals in skin. Is claimed to help reduce hyperpigmentation but evidence is missing~1.2–1.5%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.6–0.85%
Anti-aging
Glycolic acid, Acetyl tetrapeptide-11 + 4 more
Works well
What the product description says
“Peptide+ Overnight Restorative Cream features a powerful tetrapeptide complex that helps firm skin, support the density of collagen fibers and reduce the appearance of wrinkles.”
Source: Dermstore

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-11, acetyl tetrapeptide-9.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.9–7.2%
Acetyl tetrapeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%
Acetyl tetrapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.6%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.3–5.2%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.5%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.6–0.85%
Moisturizing
Acetyl tetrapeptide-11, Acetyl tetrapeptide-9 + 12 more
Works well
What the product description says
“Glycolic Acid works to even skin tone and texture while Hyaluronic Acid hydrates and plumps.”
Source: Dermstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, c12-15 alkyl benzoate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-11, acetyl tetrapeptide-9

Acetyl tetrapeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%
Acetyl tetrapeptide-9HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.6%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.3–5.2%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~3.2–3.9%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.7–2.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.55–0.85%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.5%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~2.5–3%
Arachidyl alcohol· EmollientEffect: LowUsed to soften the upper layer of the skin and create a thicker product consistency~2–2.4%
Isodecyl neopentanoate· Emollient, OcclusiveEffect: LowAn emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.~1.6–1.9%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.55–0.8%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.5–0.75%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.6–0.85%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.15–0.25%
Exfoliation
Side benefit the brand mentions · Glycolic acid, Gluconolactone
Works well
What the product description says
“Glycolic Acid works to even skin tone and texture while Hyaluronic Acid hydrates and plumps.”
Source: Lookfantastic US

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.9–7.2%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.6–0.85%

Can it cause trouble?

Irritancy
4 flagged ingredients
Low risk
We flag 4 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~5.9–7.2%est.
Albizia julibrissin bark extractA plant extract that might help to neutralize free radicals in skin. Is claimed to help reduce hyperpigmentation but evidence is missingHigh~1.2–1.5%est.
GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.6–0.85%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.15–0.25%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~4.3–5.2%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.7–2.1%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycolic acid~5.9–7.2%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid
Butyrospermum parkii butter~4.3–5.2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
C12-15 alkyl benzoate~3.2–3.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Isononyl isononanoate~2.5–3%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Arachidyl alcohol~2–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to soften the upper layer of the skin and create a thicker product consistency

More about Arachidyl alcohol
Cetearyl alcohol~1.7–2.1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Isodecyl neopentanoate~1.6–1.9%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.

More about Isodecyl neopentanoate
Albizia julibrissin bark extract~1.2–1.5%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryEvens skin toneAnti-oxidation

A plant extract that might help to neutralize free radicals in skin. Is claimed to help reduce hyperpigmentation but evidence is missing

More about Albizia julibrissin bark extract
Sodium hydroxide~1–1.2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Polyacrylate-13~0.75–1.15%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13
Gluconolactone~0.6–0.85%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneExfoliationAnti-agingMoisturizingAnti-blemishAnti-oxidation

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone
Glycerin~0.55–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Behenyl alcohol~0.55–0.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Dipentaerythrityl pentaisononanoate~0.5–0.75%
Formula
Glyceryl stearate~0.5–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Acetyl tetrapeptide-11~0.4–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-11
Acetyl tetrapeptide-9~0.35–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-9
Hyaluronic acid~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Peg-100 stearate~0.35–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Polysorbate 20~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Dimethyl isosorbide~0.2–0.35%
Formula
Irritation risk
Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide
Polyisobutene~0.2–0.35%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Arachidyl glucoside~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Arachidyl glucoside
Tocopheryl glucoside~0.2–0.35%
Formula
Irritation risk
Low
Works for
Anti-oxidation

Antioxidant that helps stabilize product formulations and, if used in higher concentration, might help neutralize free radicals in skin

More about Tocopheryl glucoside
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Caprylic/capric triglyceride~0.15–0.25%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Sodium gluconate~0.05–0.1%
Formula
Irritation risk
Low

Helps stabilize product formulations

More about Sodium gluconate
Ingredient list view

Water, Glycolic acid, Butyrospermum parkii butter, C12-15 alkyl benzoate, Isononyl isononanoate, Arachidyl alcohol, Cetearyl alcohol, Isodecyl neopentanoate, Albizia julibrissin bark extract, Sodium hydroxide, Polyacrylate-13, Gluconolactone, Glycerin, Behenyl alcohol, Dipentaerythrityl pentaisononanoate, Glyceryl stearate, Acetyl tetrapeptide-11, Acetyl tetrapeptide-9, Hyaluronic acid, Peg-100 stearate, Polysorbate 20, Dimethyl isosorbide, Polyisobutene, Arachidyl glucoside, Tocopheryl glucoside, Sodium benzoate, Caprylic/capric triglyceride, Sodium gluconate

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Amazon USPrice as of 11/3 22:28 GMT
$34.95
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Dermstore1.7 fl. oz
$86.00 Out of stock
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
GlytoneAge-Defying Peptide+ Overnight Restorative CreamYOUR PRODUCTPerricone MDCold Plasma Plus+ The Intensive Hydrating ComplexFilorgaGlobal RepairSVRTopialyse Moisturising Face + Body Cream for Dry, Sensitive + Eczema-Prone Skin of All Ages
Match—43%40%39%
Price$34.95$7.00−$27.95$103.83+$68.88$22.81−$12.14
Shared key ingredients—5 of 85 of 84 of 8
Key difference—Copper Tripeptide-1NiacinamideCamelina Sativa Seed Oil
Irritancy Low Medium High Low
Drying alcohol————
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Product summary

Judging from the ingredient list, "Glytone - Age-Defying Peptide+ Overnight Restorative Cream" works well for improving skin hydration As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (glycerin and hyaluronic acid) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Butyrospermum parkii butter, c12-15 alkyl benzoate, cetearyl alcohol, arachidyl alcohol and glyceryl stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (acetyl tetrapeptide-9 0.35% - 0.60% and acetyl tetrapeptide-11 0.40% - 0.65%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 80.00$ in the United States and for 105.20CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 21 studies and safety reviews.

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Glytone Age-Defying Peptide+ Overnight Restorative Cream
GlytoneAge-Defying Peptide+ Overnight Restorative Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.