Works for:
based on ingredients and %- Moisturizing
- Evens skin tone
- Anti-aging
- Exfoliation
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 9
Key actives
Product Summary
"Perricone MD - Cold Plasma Plus Power Duo" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, acetyl tetrapeptide-5, glycerin, sodium hyaluronate and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, dimethicone, helianthus annuus seed oil and cetearyl alcohol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- this moisturizer includes a form of retinoids (vitamin A) - retinyl palmitate 0.20% - 0.40%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
- We like that this moisturizer contains peptides (copper tripeptide-1 0.25% - 0.45%, palmitoyl tetrapeptide-7 0.30% - 0.55%, palmitoyl tripeptide-1 0.30% - 0.55%, acetyl tetrapeptide-5 0.25% - 0.45%, copper tripeptide-1 0.25% - 0.45%, palmitoyl tripeptide-1 0.60% - 0.85% and acetyl hexapeptide-8 0.65% - 0.95%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails from 85.00$ up to 115.60$ in the United States and for 106.30CA$ in Canada.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
More powerful than ever before, this 2-piece starter regimen is comprised of an advanced serum concentrate and a multi-tasking advanced eye cream that dramatically improve loss of radiance, uneven texture, uneven skin tone, discoloration, redness, enlarged pores, fine lines, wrinkles and loss of firmness.
Source: Lookfantastic CA
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, acetyl tetrapeptide-5, copper tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Evens skin tone
What does the product description say?
More powerful than ever before, this 2-piece starter regimen is comprised of an advanced serum concentrate and a multi-tasking advanced eye cream that dramatically improve loss of radiance, uneven texture, uneven skin tone, discoloration, redness, enlarged pores, fine lines, wrinkles and loss of firmness.
Source: Lookfantastic CA
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: chrysin.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Moisturizing
What does the product description say?
More powerful than ever before, this 2-piece starter regimen is comprised of an advanced serum concentrate and a multi-tasking advanced eye cream that dramatically improve loss of radiance, uneven texture, uneven skin tone, discoloration, redness, enlarged pores, fine lines, wrinkles and loss of firmness.
Source: Lookfantastic CA
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, acetyl tetrapeptide-5, copper tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1
A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
Helps soften the upper layer of the skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Might be helpful in restoring skin barrier function and calm down inflammation in skin
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps soften the upper layer of the skin and create a thicker product consistency
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps preserve products and creates a nice product texture
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A silicone that serves as an emollient. Helps create a nice non-greasy feels
Anti-oxidation
This product contains antioxidants (chrysin) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Unknown, Water, Glycerin, Isopropyl palmitate, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, Butylene glycol, Phosphatidylcholine, Tetrahexyldecyl ascorbate, Dimethyl mea, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Elaeis guineensis extract, Tetrapeptide-3, Tyrosine, Glycolic acid, Helianthus annuus seed oil, Magnesium aspartate, Zinc gluconate, Rosmarinus officinalis leaf extract, Copper gluconate, Sodium hyaluronate, Retinyl palmitate, Echium plantagineum seed oil, Hydrolyzed myrtus communis leaf extract, Copper tripeptide-1, Dimethicone, Disodium edta, Carbomer, Ceteareth-20, Cyclopentasiloxane, Caprylyl glycol, Cetearyl alcohol, Cyclohexasiloxane, Polysorbate 20, Zea mays oil, Phenoxyethanol, Sorbic acid, Unknown, Cream, Water, Isopropyl palmitate, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, Hydrolyzed jojoba esters, Ceteareth-20, Olea europaea fruit oil, Tetrahexyldecyl ascorbate, Benzyl alcohol, Phosphatidylcholine, Acetyl tetrapeptide-5, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Echium plantagineum seed oil, Helianthus annuus seed oil, Copper tripeptide-1, Magnesium aspartate, Zinc gluconate, Rosmarinus officinalis leaf extract, Copper gluconate, N-hydroxysuccinimide, Tocopherol, Sodium hyaluronate, Chrysin, Disodium edta, Hydrogenated vegetable oil, Glycerin, Dimethicone, Cyclopentasiloxane, Steareth-20, Silica, Titanium dioxide, Ci 77891, Iron oxides, Ci 77491
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- Final Report on the Safety Assessment of Isopropyl Isostearate
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
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- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines
- Zinc salts in dermatology
- An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
- Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins
- Evaluation of the effects of topical zinc gluconate in wound healing
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responses
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids
- Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review
- Antimicrobial and antioxidative activity of extracts and essential oils of Myrtus communis L.
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Content of fatty acids in corn (Zea mays L.) oil from Ecuador
- Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oil
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Anti-photoageing and anti-melanogenesis activities of chrysin
- Chrysin Protects Epidermal Keratinocytes from UVA- and UVB-Induced Damage
- Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activity