Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Anti-oxidation
- Evens skin tone
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 3
Key actives
Product Summary
Based on the ingredients included, "Perricone MD - Cold Plasma Plus+ Advanced Eye Cream Duo" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl tetrapeptide-5, glycerin, sodium hyaluronate and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, jojoba esters, dimethicone and helianthus annuus seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- This moistruizer also contains peptides (palmitoyl tripeptide-1 0.35% - 0.85%, palmitoyl tetrapeptide-7 0.35% - 0.80%, copper tripeptide-1 0.15% - 0.70% and acetyl tetrapeptide-5 0.35% - 0.85%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails for 220.00$ in the United States.
For a detailed price comparison: click here.
Moisturizing
What does the product description say?
Cold Plasma Plus+ Advanced Eye Cream Duo
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-5, copper tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1
A plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An emollient made of jojoba oil. Helps soften the skin and support its barrier function
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Might be helpful in restoring skin barrier function and calm down inflammation in skin
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps soften the upper layer of the skin and create a thicker product consistency
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Anti-aging
What does the product description say?
Smooths the appearance of crow’s feet and fine lines.
Source: Perricone MD
This product contains acetyl tetrapeptide-5, copper tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Anti-oxidation
This product contains antioxidants (chrysin) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
Evens skin tone
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: chrysin.
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging |
Total Promises Fulfilled score: 87/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Perricone MD Cold Plasma Plus+ Advanced Eye Cream Duo | Current | $220.00 | |
Hanskin Collagen Peptide Eye Cream | 47% | $21.99 | |
Dr. Lara Devgan Scientific Beauty Peptide Eye Cream | 47% | - | |
 Keys Soulcare Radiant Eye Cream with Peptides | 46% | $48.00 | |
 RoC Skincare RoC Multi Correxion Hydrate and Plump Eye Cream | 45% | $24.99 | |
 CODAGE Eye Contour Cream | 44% | $55.00 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Isopropyl palmitate, Cetearyl alcohol, Glyceryl stearate, Jojoba esters, Peg-100 stearate, Ceteareth-20, Benzyl alcohol, Hydrogenated olive oil, Olea europaea fruit oil, Tetrahexyldecyl ascorbate, Phosphatidylcholine, Acetyl tetrapeptide-5, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Echium plantagineum seed oil, Helianthus annuus seed oil, Copper tripeptide-1, Magnesium aspartate, Zinc gluconate, Sodium hyaluronate, Rosmarinus officinalis leaf extract, Copper gluconate, N-hydroxysuccinimide, Chrysin, Disodium edta, Dimethicone, Glycerin, Butylene glycol, Steareth-20, Dimethicone crosspolymer, Silica, Titanium dioxide, Ci 77891, Iron oxides, Ci 77491
- Final Report on the Safety Assessment of Isopropyl Isostearate
- Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oil
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds
- Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines
- Zinc salts in dermatology
- An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
- Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins
- Evaluation of the effects of topical zinc gluconate in wound healing
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responses
- Anti-photoageing and anti-melanogenesis activities of chrysin
- Chrysin Protects Epidermal Keratinocytes from UVA- and UVB-Induced Damage
- Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activity
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Glycerol and the skin: holistic approach to its origin and functions