BIOHEAL BOH

BIOHEAL BOH Probioderm 3D Lifting Eye & Wrinkle Cream

Name: BIOHEAL BOH - Probioderm 3D Lifting Eye & Wrinkle Cream
Brand: BIOHEAL BOH

Efficacy100/100IrritancyMedium

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Works for

2 of 2 advertised claims delivered

Anti-aging

Adenosine, Palmitoyl hexapeptide-12 + 16 more

Strong evidence

What the product description says

“Probioderm 3D Lifting Eye & Wrinkle Cream”

Source: W cosmetics

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-1, acetyl hexapeptide-8, acetyl tetrapeptide-5, acetyl tetrapeptide-9, copper tripeptide-1, dipeptide diaminobutyroyl benzylamide diacetate, hexapeptide-9, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tripeptide-8, tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Acetyl tetrapeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl tetrapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.25–0.4%

Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Hexapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Nonapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Palmitoyl tripeptide-8Key activeEffect: Medium~0.2–0.4%

Acetyl hexapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.4%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%

Moisturizing

Acetyl hexapeptide-8, Acetyl tetrapeptide-5 + 42 more

Strong evidence

What the product description says

“An eye cream that helps firm the delicate and thin skin around eyes and helps improve skin elaticity for a youthful plump look.”

Source: W cosmetics

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, betaine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-1, acetyl hexapeptide-8, acetyl tetrapeptide-5, acetyl tetrapeptide-9, copper tripeptide-1, dipeptide diaminobutyroyl benzylamide diacetate, hexapeptide-9, nonapeptide-1, palmitoyl hexapeptide-12, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, palmitoyl tripeptide-8, panthenol, tripeptide-1

Vinyl dimethiconeKey active· EmollientEffect: HighA type of silicone that helps to create a nice product texture and soften the upper layer of the skin~0.4–0.6%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Acetyl tetrapeptide-5Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl tetrapeptide-9HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tripeptide-8HeroEffect: High~0.2–0.4%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.2–0.4%

Polyglycerin-3Key active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.95–1.15%

PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1.2–1.5%

Stearyl dimethiconeKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.5–0.75%

Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl hexapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.2–0.4%

Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.4%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.25–0.4%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.2–3.9%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.25–0.4%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.25–0.4%

DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.25–0.45%

Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

FructooligosaccharidesKey active· HumectantEffect: HighHelp attract water to the upper layer of the skin~0.25–0.4%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–4.8%

Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.25–0.45%

Hexapeptide-9Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.4%

InulinKey activeEffect: HighHelps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking~0.25–0.4%

Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~1.4–1.7%

Laminaria japonica extractKey activeEffect: HighSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties~0.25–0.45%

Nonapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%

Diisostearyl malateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin~1.9–2.4%

Elaeis guineensis oilKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.25–0.45%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.3–2.8%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.25–0.5%

Lactobacillus ferment lysateKey activeEffect: MediumA "broth" with parts of dead cells of lactobacteria. Might be helpful supporting diverse microbiome in skin, but evidence is lacking~4.6–5.7%

AlginEffect: LowUsed to thicken product formulation. Can help attract water to the upper layer of the skin~0.25–0.45%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.25–0.5%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.35–0.65%

Can it cause trouble?

Irritancy

2 strong irritants: Eclipta prostrata leaf extract, Parfum

Medium risk

We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Eclipta prostrata leaf extractA plant extract that is mostly used as a fragrance. Might have some anti-oxidant effectHigh~0.25–0.4%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.4%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.2–3.9%est.

Diisostearyl malateHelps to soften the upper layer of the skinMedium~1.9–2.4%est.

1,2-hexanediolA preservativeMedium~0.4–0.6%est.

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.3–0.55%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.2–0.4%est.

Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.25–0.45%est.

Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.

Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.25–0.45%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Laminaria japonica extractSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties3/5~0.25–0.45%est.

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.25–0.5%est.

AlginUsed to thicken product formulation. Can help attract water to the upper layer of the skin3/5~0.25–0.45%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.3–2.8%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Lactobacillus ferment lysate~4.6–5.7%

Key active

Irritation risk: Low

Works for

Moisturizing

A "broth" with parts of dead cells of lactobacteria. Might be helpful supporting diverse microbiome in skin, but evidence is lacking

More about Lactobacillus ferment lysate

Glycerin~3.9–4.8%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Caprylic/capric triglyceride~3.2–3.9%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Cetearyl alcohol~2.3–2.8%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Diisostearyl malate~1.9–2.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

CleansingMoisturizing

Helps to soften the upper layer of the skin

More about Diisostearyl malate

Cetearyl olivate~1.6–2%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Cetearyl olivate

Lactobacillus ferment~1.4–1.7%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-oxidationReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment

Polymethylsilsesquioxane~1.2–1.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane

Polyglycerin-3~0.95–1.15%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin

More about Polyglycerin-3

Phytosteryl/behenyl/octyldodecyl lauroyl glutamate~0.65–1%

Formula

Irritation risk: Low

More about Phytosteryl/behenyl/octyldodecyl lauroyl glutamate

Sorbitan olivate~0.55–0.8%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan olivate

Stearyl dimethicone~0.5–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Stearyl dimethicone

1,2-hexanediol~0.4–0.6%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Butylene glycol~0.35–0.65%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Ammonium acryloyldimethyltaurate/vp copolymer~0.35–0.65%

Formula

Irritation risk: Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer

Vinyl dimethicone~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of silicone that helps to create a nice product texture and soften the upper layer of the skin

More about Vinyl dimethicone

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.3–0.55%

Irritant · medium

Irritation risk: Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer

Dimethicone/vinyl dimethicone crosspolymer~0.3–0.5%

Formula

Irritation risk: Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer

Hydroxyacetophenone~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Octadecene~0.25–0.45%

Formula

Irritation risk: Low

More about Octadecene

Euphorbia cerifera wax~0.25–0.5%

Formula

Irritation risk: Low

More about Euphorbia cerifera wax

Dipropylene glycol~0.2–0.35%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Elaeis guineensis oil~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil

Polyacrylate-13~0.25–0.45%

Formula

Irritation risk: Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13

Panthenol~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Ethylhexylglycerin~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Xanthan gum~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Laminaria japonica extract~0.25–0.45%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Seaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties

More about Laminaria japonica extract

Eclipta prostrata leaf extract~0.25–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that is mostly used as a fragrance. Might have some anti-oxidant effect

More about Eclipta prostrata leaf extract

Glyceryl acrylate/acrylic acid copolymer~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer

Parfum~0.2–0.4%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Hydrogenated polyisobutene~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Adenosine~0.25–0.4%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Sorbitan isostearate~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Polyglyceryl-10 myristate~0.25–0.45%

Formula

Irritation risk: Low

More about Polyglyceryl-10 myristate

Fructooligosaccharides~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Help attract water to the upper layer of the skin

More about Fructooligosaccharides

Disodium edta~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Polyglyceryl-10 laurate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate

Beta-glucan~0.25–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationAnti-agingAnti-blemishAnti-oxidation

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan

Hydrogenated lecithin~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Ethylhexyl palmitate~0.25–0.5%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

Malt extract~0.25–0.4%

Formula

Irritation risk: Low

More about Malt extract

Hydrolyzed hyaluronic acid~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Cyanocobalamin~0.25–0.4%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Acetyl tetrapeptide-5~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-5

Betaine~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Arginine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Carbomer~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Maltodextrin~0.25–0.45%

Formula

Irritation risk: Low

Works for

Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin

Tocopherol~0.25–0.45%

Formula

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Propanediol~0.25–0.5%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Sodium phosphate~0.25–0.45%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Sodium phosphate

Caprylyl glycol~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Algin~0.25–0.45%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Used to thicken product formulation. Can help attract water to the upper layer of the skin

More about Algin

Soluble proteoglycan~0.25–0.4%

Formula

Irritation risk: Low

More about Soluble proteoglycan

Biosaccharide gum-4~0.25–0.4%

Formula

Irritation risk: Low

Helps improve the product texture

More about Biosaccharide gum-4

Fructan~0.25–0.4%

Formula

Irritation risk: Low

More about Fructan

Nonapeptide-1~0.25–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nonapeptide-1

Acetyl tetrapeptide-9~0.25–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-9

Acetyl hexapeptide-1~0.25–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-1

Inulin~0.25–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-blemish

Helps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking

More about Inulin

Acetyl hexapeptide-8~0.25–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Dextran~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran

Palmitoyl tripeptide-8~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

More about Palmitoyl tripeptide-8

Copper tripeptide-1~0.25–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Palmitoyl tetrapeptide-7~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Dipeptide diaminobutyroyl benzylamide diacetate~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate

Tripeptide-1~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1

Palmitoyl pentapeptide-4~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4

Palmitoyl tripeptide-5~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Palmitoyl tripeptide-1~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl hexapeptide-12~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12

Hexapeptide-9~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-9

Pentapeptide-3~0.15–0.3%

Formula

Irritation risk: Low

More about Pentapeptide-3

Saponins~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

More about Saponins

Mineral salts~0.15–0.25%

Formula

Irritation risk: Low

Used to thicked product formulations. Might help to add minerals to the surface of the skin

More about Mineral salts

Disodium phosphate~0.1–0.15%

Formula

Irritation risk: Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate

Oligopeptide-2~0.1–0.15%

Formula

Irritation risk: Low

More about Oligopeptide-2

Ingredient list view

Water, Lactobacillus ferment lysate, Glycerin, Caprylic/capric triglyceride, Cetearyl alcohol, Diisostearyl malate, Cetearyl olivate, Lactobacillus ferment, Polymethylsilsesquioxane, Polyglycerin-3, Phytosteryl/behenyl/octyldodecyl lauroyl glutamate, Sorbitan olivate, Stearyl dimethicone, 1,2-hexanediol, Butylene glycol, Ammonium acryloyldimethyltaurate/vp copolymer, Vinyl dimethicone, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Dimethicone/vinyl dimethicone crosspolymer, Hydroxyacetophenone, Octadecene, Euphorbia cerifera wax, Dipropylene glycol, Elaeis guineensis oil, Polyacrylate-13, Panthenol, Ethylhexylglycerin, Xanthan gum, Laminaria japonica extract, Eclipta prostrata leaf extract, Glyceryl acrylate/acrylic acid copolymer, Parfum, Hydrogenated polyisobutene, Adenosine, Sorbitan isostearate, Polyglyceryl-10 myristate, Fructooligosaccharides, Disodium edta, Polyglyceryl-10 laurate, Beta-glucan, Hydrogenated lecithin, Ethylhexyl palmitate, Malt extract, Hydrolyzed hyaluronic acid, Cyanocobalamin, Acetyl tetrapeptide-5, Betaine, Arginine, Carbomer, Maltodextrin, Tocopherol, Propanediol, Sodium phosphate, Caprylyl glycol, Algin, Soluble proteoglycan, Biosaccharide gum-4, Fructan, Nonapeptide-1, Acetyl tetrapeptide-9, Acetyl hexapeptide-1, Inulin, Acetyl hexapeptide-8, Dextran, Palmitoyl tripeptide-8, Copper tripeptide-1, Palmitoyl tetrapeptide-7, Dipeptide diaminobutyroyl benzylamide diacetate, Tripeptide-1, Palmitoyl pentapeptide-4, Palmitoyl tripeptide-5, Palmitoyl tripeptide-1, Palmitoyl hexapeptide-12, Hexapeptide-9, Pentapeptide-3, Saponins, Mineral salts, Disodium phosphate, Oligopeptide-2

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	BIOHEAL BOHProbioderm 3D Lifting Eye & Wrinkle CreamYOUR PRODUCT	SWANICOCOPeptine Biome Eye Cream
Match	—	54%
Price	$38.68	$18.00−$20.68
Shared key ingredients	—	21 of 35
Key difference	—	Acetyl Dipeptide-1 Cetyl Ester
Irritancy	Medium	Medium
Drying alcohol	—	—
	View product	Shop

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Product summary

Based on the ingredient list, "BIOHEAL BOH - Probioderm 3D Lifting Eye & Wrinkle Cream" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, acetyl tetrapeptide-5, hexapeptide-9, panthenol and arginine) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Palmitoyl tetrapeptide-7, tripeptide-1, vinyl dimethicone, arginine and caprylic/capric triglyceride in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

This moisturizer also contains Peptides (oligopeptide-1 0.20% - 0.40%, hexapeptide-9 0.20% - 0.40%, palmitoyl hexapeptide-12 0.20% - 0.40%, palmitoyl pentapeptide-4 0.20% - 0.40%, palmitoyl tripeptide-5 0.20% - 0.40%, palmitoyl tetrapeptide-7 0.25% - 0.50%, tripeptide-1 0.25% - 0.45%, copper tripeptide-1 0.20% - 0.40%, dipeptide diaminobutyroyl benzylamide diacetate 0.20% - 0.40%, palmitoyl tripeptide-8 0.20% - 0.40%, acetyl hexapeptide-8 0.25% - 0.40%, acetyl hexapeptide-1 0.25% - 0.45%, acetyl tetrapeptide-9 0.25% - 0.45%, nonapeptide-1 0.25% - 0.50% and acetyl tetrapeptide-5 0.30% - 0.55%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Adenosine 0.35% - 0.65%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Panthenol (pro-vitamin B5) at about 0.55% - 0.80% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 31 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
The effect of probiotics on immune regulation, acne, and photoagingncbi.nlm.nih.gov
3
Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face studyncbi.nlm.nih.gov
4
Use of Probiotics for Dermal Applicationsresearchgate.net
5
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
6
Genetic Architecture of Palm Oil Fatty Acid Composition in Cultivated Oil Palm (Elaeis guineensis Jacq.) Compared to Its Wild Relative E. oleifera (H.B.K) Cortésjournals.plos.org
7
Nutrient composition of Nigerian palm kernel from the dura and tenera varieties of the oil palm (Elaeis guineensis)sciencedirect.com
8
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
9
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
10
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
11
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
12
In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Responseresearchgate.net
13
β-Glucans: Multi-Functional Modulator of Wound Healingncbi.nlm.nih.gov
14
Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucanonlinelibrary.wiley.com
15
Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Reviewonlinelibrary.wiley.com
16
Anticancer properties of low molecular weight oat beta-glucan – An in vitro studysciencedirect.com
17
A critical review on production and industrial applications 2 of beta-glucanssciencedirect.com
18
Improving skin function with CM-glucan, a biological response modifier from yeastonlinelibrary.wiley.com
19
Preparation, characterization, and biological properties of β-glucansncbi.nlm.nih.gov
20
Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatusncbi.nlm.nih.gov
21
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
22
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
23
Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trialpubmed.ncbi.nlm.nih.gov
24
Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasisncbi.nlm.nih.gov
25
Vitamin E in dermatologyncbi.nlm.nih.gov
26
Vitamin E and Skin Healthlpi.oregonstate.edu
27
Probiotics and prebiotics potential for the care of skin, female urogenital tract, and respiratory tractlink.springer.com
28
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
29
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
30
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
31
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com

BIOHEAL BOHProbioderm 3D Lifting Eye & Wrinkle Cream

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