PRODUCT REVIEW
Noble Panacea The Absolute Intense Renewal Serum
Buy from Amazon US $415.00
More options from: $395.00
Price as of 3/10/2024 1:38 GMT.
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PCA SKIN - Intensive Age Refining Treatment 0.5 Percent Pure Retinol Night
Price: $115
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What can the product work for?
Anti-aging
What does the product description say?
Key Benefits Reasons to Believe An ultra-powerful serum to treat all signs of natural aging Increases skin cells activity, energy and regeneration High-active antioxidant nutritive complex Fortifies skin from future degradation Restores natural fullness and volume Boosts collagen and elasticity Redefines facial contours, skin is visibly tightened and lifted Hydrates and nourishes to counteract water loss Smooths fine lines and deep wrinkles Deeply exfoliates to support cell turnover and minimizing pores Refines and softens skin for a smooth, even texture Revitalizes the skin
retinol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
glycolic acid
0.15% -
0.25%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
ubiquinone
0.3% -
0.5%
Irritation risk:
Concentration: Effectiveness:
LOW
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
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Moisturizing
What does the product description say?
Key Benefits Reasons to Believe An ultra-powerful serum to treat all signs of natural aging Increases skin cells activity, energy and regeneration High-active antioxidant nutritive complex Fortifies skin from future degradation Restores natural fullness and volume Boosts collagen and elasticity Redefines facial contours, skin is visibly tightened and lifted Hydrates and nourishes to counteract water loss Smooths fine lines and deep wrinkles Deeply exfoliates to support cell turnover and minimizing pores Refines and softens skin for a smooth, even texture Revitalizes the skin
ubiquinone
0.3% -
0.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
betaine
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps attract water to the upper layer of the skin and improves the product texture
ceramide ng
0.15% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
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Anti-blemish
retinol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
glycolic acid
0.15% -
0.25%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
ginkgo biloba leaf extract
0.1% -
0.25%
Irritation risk:
Concentration: Effectiveness:
LOW
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
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Evens skin tone
retinol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
glycolic acid
0.15% -
0.25%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
punica granatum extract
0.1% -
0.2%
Irritation risk:
Concentration: Effectiveness:
LOW
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
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Exfoliation
glycolic acid
0.15% -
0.25%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
retinol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
gluconolactone
0.1% -
0.15%
Irritation risk:
Concentration: Insufficient!
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
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Anti-oxidation
superoxide dismutase
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
retinol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
ubiquinone
0.3% -
0.5%
Irritation risk:
Concentration: Effectiveness: HIGH
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
Show more
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 1
Potential irritants
rosa damascena flower water
0.55% -
0.8%
Irritation risk:
Works for:
Moisturizing,
Anti-oxidation
Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating
retinol
0.2% -
0.35%
Irritation risk:
Works for:
Exfoliation,
Anti-blemish,
Evens skin tone,
Mattifying,
Anti-aging,
Anti-oxidation
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Show more
Comodogenic ingredients
chondrus crispus extract
0.15% -
0.3%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency
User reviews (0)
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LOW
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
0.4% -
0.6%
Irritation risk:
Works for:
Moisturizing,
Anti-aging,
Anti-blemish,
Evens skin tone,
Reduces irritation,
Anti-inflammatory,
Antibacterial,
Reduces redness
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
centella asiatica extract
0.2% -
0.35%
Irritation risk:
Works for:
Anti-inflammatory,
Moisturizing,
Reduces redness,
Reduces irritation,
Anti-oxidation,
Anti-aging,
Anti-blemish
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
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Potential irritants
rosa damascena flower water
0.55% -
0.8%
Irritation risk:
Works for:
Moisturizing,
Anti-oxidation
Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating
retinol
0.2% -
0.35%
Irritation risk:
Works for:
Exfoliation,
Anti-blemish,
Evens skin tone,
Mattifying,
Anti-aging,
Anti-oxidation
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Show more
Comodogenic ingredients
chondrus crispus extract
0.15% -
0.3%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency
All ingredients
aloe barbadensis leaf juice
6.1% -
7.5%
Irritation risk:
Works for:
Moisturizing,
Reduces irritation,
Reduces redness,
Anti-inflammatory,
Antibacterial,
Anti-aging,
Anti-blemish
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
glycerin
3.8% -
4.6%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
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Ingredient list view
Water, Aloe barbadensis leaf juice, Glycerin, Hydrogenated ethylhexyl olivate, C13-15 alkane, Propanediol, Carthamus tinctorius oleosomes, Cyclodextrin, Potassium hydroxide, Allantoin, Rosa damascena flower water, Panthenol, Niacinamide, Calanthe discolor extract, Teprenone, Sodium hyaluronate, Ubiquinone, Simmondsia chinensis seed oil, Retinol, Camellia sinensis leaf extract, Aspalathus linearis leaf extract, Ascorbyl glucoside, Avena sativa kernel extract, Camellia sinensis leaf oil, Argania spinosa kernel oil, Ginkgo biloba leaf extract, Tocopherol, Ascorbyl palmitate, Magnesium ascorbyl phosphate, Glycolic acid, Calendula officinalis flower, Tocopheryl acetate, Helianthus annuus seed oil, Oryza sativa bran extract, Punica granatum extract, Citrus aurantium dulcis callus culture extract, Unknown, Tocopherol, Ascorbic acid, Chondrus crispus extract, Persea gratissima oil, Garcinia mangostana peel extract, Coffea arabica seed extract, Phospholipids, Ceramide ng, Centella asiatica extract, Citrus limon fruit extract, Unknown, Lac, Rubus idaeus seed oil, Helianthus annuus extract, Calcium gluconate, Rosa canina fruit oil, Glycine soja seed extract, Dimethylmethoxy chromanol, Leuconostoc/radish root ferment filtrate, Orobanche rapum extract, Thymus vulgaris extract, Citrus aurantium dulcis fruit extract, Vaccinium myrtillus fruit extract, Nigella sativa seed oil, Ethylhexylglycerin, Buddleja davidii extract, Acer saccharum extract, Sodium hydroxide, Tetrasodium glutamate diacetate, Saccharum officinarum extract, Betaine, Acacia senegal gum, Caprylic/capric triglyceride, Morinda citrifolia fruit extract, Benzoic acid, Hydrogenated olive oil unsaponifiables, Lycium barbarum fruit extract, Euterpe oleracea fruit extract, Saccharide isomerate, Rosmarinus officinalis leaf extract, Superoxide dismutase, Chlorphenesin, Xanthan gum, Sodium benzoate, Sorbic acid, Phenoxyethanol, Gluconolactone
Sources
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- Cyclodextrins: new drug delivery systems in dermatology
- Profile of wound healing process induced by allantoin
- Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts
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- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
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- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Rooibos (Aspalathus linearis) beyond the farm gate: From herbal tea to potential phytopharmaceutical
- The Roles of Vitamin C in Skin Health
- Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
- Natural vegetable fats in the prevention of irritant contact dermatitis
- Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmetics
- Cosmeceutical Critique: Ginkgo Biloba
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Topical L-ascorbic acid: percutaneous absorption studies
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation
- Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects
- Safety Assessment of Punica granatum -Derived Ingredients as Used in Cosmetics
- Effect of green Coffea arabica L. seed oil on extracellular matrix components and water-channel expression in in vitro and ex vivo human skin models
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- Centella asiatica in Dermatology: An Overview
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics
- Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin
- Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmetics
- Photosensitivity in children: An approach to diagnosis and management
- Lonicera caerulea and Vaccinium myrtillus fruit polyphenols protect HaCaT keratinocytes against UVB-induced phototoxic stress and DNA damage
- Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.
- Water-soluble polysaccharide from dried Lycium barbarum fruits: Isolation, structural features and antioxidant activity
- Lycium barbarum polysaccharide protects human keratinocytes against UVB-induced photo-damage
- Lycium Barbarum and Human Health
- Total Oxidant Scavenging Capacity of Euterpe oleracea Mart. (Açaí) Seeds and Identification of Their Polyphenolic Compounds
- Euterpe oleracea, Matricaria chamomilla, and Camellia sinensis as promising ingredients for development of skin care formulations
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responses
- A novel efficient and safe treatment for atopic dermatitis: Topical superoxide dismutase (SOD).
- Novel topical agent containing superoxide dismutase 100 000 IU and 4% of plant extracts as a mono-therapy for atopic dermatitis
- Copper/Zinc Superoxide Dismutase in Human Skin: Current Knowledge
- Photoprotective Effect of Topically Applied Superoxide Dismutase on Sunburn Reaction in Comparison with Sunscreen
- The role of superoxide dismutase (SOD) in skin disorders
- Topical formulations with superoxide dismutase: Influence of formulation composition on physical stability and enzymatic activity
- Skin protective effects of RM191A, a novel superoxide dismutase mimetic
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
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