Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Exfoliation
- Anti-blemish
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 2
Key actives
Product Summary
"Neutrogena - Skin Vitals Regenerate Duo" is effective for: Exfoliation, Anti-blemish, Anti-aging and Evens skin tone
This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.20% - 0.35%) it cannot have a noticeable benefit for the skin.
- This product contains an effective form of Retinoids (vitamin A): retinol 0.25% - 0.50%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
- Humectants (sodium hyaluronate 0.25% - 0.45%, glycerin 0.35% - 0.65%, hydrolyzed hyaluronic acid 0.30% - 0.60% and glycerin 5.40% - 6.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 47.98$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
Improve the look of fine lines in one week & protect skin from sun exposure.
Source: Neutrogena
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Anti-oxidation
This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
An anti-oxidant. Is also called 6-paradol. It might be able to neutralize free radicals in skin. The manufacturer claims that it is able to stimulate synthesis of hyaluronic acid in skin, but there is no evidence of effectiveness of this ingredient so far. The only evidence of efficacy for this ingredient so far come from small lab tests. This ingredient comes together with Caprylic/Capric Triglyceride as part of the complex called SymDecanox HA produced by a cosmetic ingredient supplier Symrise.
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Moisturizing
What does the product description say?
This fragrance-free skincare set contains a regenerating retinol cream & an SPF 50 moisturizer to smooth & protect skin.
Source: Neutrogena
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydrolyzed hyaluronic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
Help soften the upper layer of the skin and create a nice product consistency
Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
Helps preserve products and creates a nice product texture
A type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
An anti-oxidant. Is also called 6-paradol. It might be able to neutralize free radicals in skin. The manufacturer claims that it is able to stimulate synthesis of hyaluronic acid in skin, but there is no evidence of effectiveness of this ingredient so far. The only evidence of efficacy for this ingredient so far come from small lab tests. This ingredient comes together with Caprylic/Capric Triglyceride as part of the complex called SymDecanox HA produced by a cosmetic ingredient supplier Symrise.
Used to preserve products, dissolve other ingredients and create a nice product texture
Used to create a nice product consistency while softening the upper layer of the skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score: 87/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Neutrogena Skin Vitals Regenerate Duo | Current | $47.98 | |
RoC Skincare RoC Retinol Correxion Line Smoothing Max Hydration | 84% | $21.59 | |
 Aesthetics Rx A Serum Retinol Restorative | 82% | $119.00 | |
First Aid Beauty Skin Lab Retinol Serum .25% Pure Concentrate | 82% | $51.00 | |
 Jan Marini Age Intervention Retinol Plus | 82% | $81.00 | |
 Formula 10.0.6 In The Deep Vitamin A Nourishing Retinol Serum | 81% | $19.49 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Butyl methoxydibenzoylmethane, Homosalate, Ethylhexyl salicylate, Octocrylene, Water, Butyloctyl salicylate, Glycerin, Alcohol denat., Silica, Caprylyl methicone, Caprylic/capric triglyceride, Aluminum starch octenylsuccinate, Dimethicone, Polyurethane-62, Phenoxyethanol, Pentylene glycol, Styrene/acrylates copolymer, Sodium acryloyldimethyltaurate/vp crosspolymer, Acrylates/dimethicone copolymer, Glyceryl stearate, Chlorphenesin, Menthyl lactate, Tocopheryl acetate, Disodium edta, Trideceth-6, Hydrolyzed hyaluronic acid, Hydroxymethoxyphenyl decanone, Sodium hydroxide, Water, Pentaerythrityl tetraethylhexanoate, Glycerin, Dimethicone, Ppg-15 stearyl ether, Stearyl alcohol, Cetearyl alcohol, Butylene glycol, Glyceryl behenate, Ceteareth-20, Isohexadecane, Dimethicone crosspolymer, Cyclopentasiloxane, Cellulose, Sodium polyacrylate, Phenoxyethanol, Caprylyl glycol, Sodium acryloyldimethyltaurate/vp crosspolymer, Polyacrylamide, C13-14 isoparaffin, Chlorphenesin, Polysorbate 20, Hydrolyzed myrtus communis leaf extract, Retinol, Bht, Sodium hyaluronate, Disodium edta, Sodium hydroxide, Laureth-7, Ascorbic acid
- Opinion on Homosalate - Scientific Committee on Consumer Products
- Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate
- Glycerol and the skin: holistic approach to its origin and functions
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Amended Safety Assessment of Acrylates Copolymers as Used in Cosmetics
- Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- COMPOSITION COMPRISING A CROSSLINKED HYALURONIC ACID (HA) IN COMBINATION WITH A LOW-MOLECULAR HA AND/OR AN AGENT STIMULATING ENDOGENOUS HA SYNTHESIS
- Designing topical hyaluronic acid technology—Size does matter
- Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics
- Final report on the safety assessment of PPG-11 and PPG-15 stearyl ethers
- Safety Assessment of Isoparaffins as Used in Cosmetics
- Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review
- Antimicrobial and antioxidative activity of extracts and essential oils of Myrtus communis L.
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care