Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Evens skin tone
- Anti-blemish
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"Neogen - Surmedic Super Glutathione 100 Bright Ampoule" is effective for: Anti-inflammatory, Moisturizing, Anti-aging, Evens skin tone and Anti-blemish
Ingredient callouts
- A good concentration of Niacinamide (3.00% - 3.70%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.55% - 0.85%) it cannot have a noticeable benefit for the skin.
- Adenosine 0.95% - 1.15%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Humectants (sodium lactate 0.25% - 0.45%, sodium hyaluronate 0.25% - 0.50%, panthenol 0.45% - 0.70%, hydrolyzed collagen 0.45% - 0.65% and glycerin 1.20% - 1.50%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 20.00$ in the United States.
For a detailed price comparison: click here.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: centella asiatica extract.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Anti-oxidation
This product contains antioxidants (glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - centella asiatica extract, ficus carica fruit extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A plant extract. Can have an anti-oxidant effect, but can also contain irritants
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A plant extract that might help neutralize free radicals in skin
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
A plant extract that may contain a small amount of essential oils. Might be helpful in neutralizing free radicals in skin
A plant extract that might have anti-oxidant properties
A plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin
A plant extract that might have anti-oxidant properties and help even out skin tone, but solid evidence is lacking
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
A fruit extact. Might have some anti-oxidant properties
An essential oil. Can be irritating. Can become an allergen with oxidation
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin
A plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect
A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza uralensis root extract, morus alba bark extract.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A plant extract that might have anti-oxidant properties and help even out skin tone, but solid evidence is lacking
Licorice root extract. Might be helpful in reducing hyperpigmentation
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Moisturizing
What does the product description say?
Providing intensive therapy for tired complexions, this ampoule is packed full of glutathione, various vitamins and hyaluronic acid to restore skin to fully moisturized radiance.
Source: Yesstyle
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydrolyzed collagen.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Plant oil that helps soften the upper layer of the skin
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A plant extract that helps soften the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing |
Total Promises Fulfilled score: 100/100.
We receive a small commission for purchases made through these links at no cost for you. Thank you for your support! Learn more
Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
User reviews (0)
Averages from community submissions.
No reviews yet for this product.
Be the first to share your experience!
Tried this product?
Help capture what the ingredient list can't—texture, finish, pilling, scent, and more. Answer what you can, skip the rest.
Takes ~30 seconds.
Reviews are shown in aggregate. No personal details.
| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 NEOGEN X SUR.MEDIC Surmedic Super Glutathione 100 Bright Ampoule | Current | $20.00 | |
 Vitabrid US 13 YEARS YOUNGER WRINKLE SERUM PROFESSIONAL: REGULAR PRICE | Vitabrid US | 78% | $83.00 | |
 VITABRID INC. Wrinkle Serum Professional | 78% | $83.00 | |
 Dr. Ceuracle Hyal Reyouth Ampoule | 64% | $34.00 | |
 TONYMOLY Vital Vita 12 Synergy Serum | 64% | - | |
 JMsolution Marine Luminous Pearl Deep Moisture Ampoule Serum | 63% | $35.40 |
Key Actives
Potential irritants
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
Ingredient list view
Hamamelis virginiana water, Dimethicone, Cyclopentasiloxane, Glutathione, Niacinamide, Polysorbate 20, Polysilicone-11, Dipropylene glycol, Glycerin, Adenosine, Riboflavin, Ascorbic acid, Thiamine hcl, Panthenol, Centella asiatica extract, Cucumis sativus extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Saussurea involucrata extract, Sodium hyaluronate, Pearl extract, Hydrolyzed collagen, Helianthus annuus seed oil, Rosmarinus officinalis leaf extract, Panax ginseng root extract, Chamomilla recutita flower extract, Chrysanthellum indicum extract, Oenothera biennis flower extract, Camellia japonica seed extract, Fragaria chiloensis fruit extract, Melissa officinalis leaf extract, Aesculus hippocastanum extract, Portulaca oleracea extract, Ficus carica fruit extract, Adansonia digitata leaf extract, Lilium tigrinum extract, Prunus persica fruit extract, Achillea millefolium flower extract, Persea gratissima fruit extract, Gypsophila paniculata root extract, Mentha rotundifolia leaf extract, Sambucus nigra fruit extract, Nelumbo nucifera seed extract, Nelumbo nucifera flower extract, Rhus semialata gall extract, Cananga odorata flower extract, Jasminum officinale flower extract, Dioscorea japonica root extract, Symphytum officinale leaf extract, Lupinus albus seed extract, Simmondsia chinensis seed extract, Vaccinium myrtillus leaf extract, Piper methysticum leaf/root/stem extract, Fagus sylvatica bud extract, Iris versicolor extract, Tocopherol, Glycyrrhiza uralensis root extract, Morus alba bark extract, Origanum vulgare leaf extract, Salix alba bark extract, Leontopodium alpinum callus culture extract, Opuntia coccinellifera fruit extract, Allantoin, Lavandula angustifolia oil, Citrus nobilis peel oil, Rosmarinus officinalis leaf oil, Pelargonium graveolens flower oil, Polyacrylate-13, Phenoxyethanol, Polyisobutene, Ethylhexylglycerin, Cellulose gum, Sorbitan isostearate, Sodium lactate, Sodium gluconate, Disodium edta, Citrus aurantium bergamia fruit oil, Butylene glycol, 1,2-hexanediol, Water
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Glutathione as a skin whitening agent: Facts, myths, evidence and controversies
- Glutathione for skin lightening: a regnant myth or evidence-based verity?
- Glutathione for skin lightening for dermatologists and cosmetologists
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Glycerol and the skin: holistic approach to its origin and functions
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- Contact dermatitis due to Madecassol
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Nuclear Factor Kappa B Inhibition as a Therapeutic Target of Nutraceuticals in Arthritis, Osteoarthritis, and Related Inflammation
- Resveratrol as an active ingredient for cosmetic and dermatological applications: a review
- Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants
- Flavonoids in Treating Psoriasis
- Improvement of skin barrier dysfunction by Scutellaria baicalensis GEOGI extracts through lactic acid fermentation
- Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responses
- Ginseng in Dermatology: A Review
- Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
- Volatile Aroma Composition of Chrysanthemum indicum L. Flower Oil
- Contact dermatitis to extract of horse chestnut (esculin)
- Portulaca oleracea (purslane)
- Amended Safety Assessment of Achillea Millefolium-Derived Ingredients as Used in Cosmetics
- Assessment report on Sambucus nigra L., fructus
- SKIN PROTECTION AGAINST SOLAR UV RADIATION BY NATURAL PLANT PRODUCTS: EXTRACTS FROM ELDER FRUIT (SAMBUCUS NIGRA L.)
- Symphytum Species: A Comprehensive Review on Chemical Composition, Food Applications and Phytopharmacology
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Mulberroside F Isolated from the Leaves of Morus alba Inhibits Melanin Biosynthesis
- Morus alba L. nature's functional tonic
- Efficacy and Safety of White Willow Bark (Salix alba) Extract
- An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging
- Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells
- Profile of wound healing process induced by allantoin
- Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics
- Oxidized citrus oil (R-limonene): A frequent skin sensitizer in Europe
- Air oxidation increases skin irritation from fragrance terpenes
- Assessment report on Rosmarinus officinalis L., aetheroleum and Rosmarinus officinalis L., folium
- Screening of plant extracts for antimicrobial activity against bacteria and yeasts with dermatological relevance
- Occupational contact dermatitis due to essential oils
- The in vitro antimicrobial activity and chemometric modelling of 59 commercial essential oils against pathogens of dermatological relevance
- Antimicrobial and Antioxidant Properties of Rosemary and Sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) Essential Oils
- Chemical Composition, Plant Genetic Differences, Antimicrobial and Antifungal Activity Investigation of the Essential Oil of Rosmarinus officinalis L.
- Fragrance Compound Geraniol Forms Contact Allergens on Air Exposure. Identification and Quantification of Oxidation Products and Effect on Skin Sensitization
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Oxidized citrus oil (R-limonene): A frequent skin sensitizer in Europe
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols