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MyChelle Dermaceuticals Supreme Polypeptide Cream
MyChelle Dermaceuticals

MyChelle Dermaceuticals Supreme Polypeptide Cream

Efficacy58/100IrritancyHigh
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Works for

2 of 3 advertised claims delivered

Moisturizing
Palmitoyl tripeptide-38, Palmitoyl tripeptide-5 + 22 more
Strong evidence
What the product description says
“Strengthen Multi-peptide and nutrient-rich cream enriched with 4 powerful anti-aging peptides that help strengthen skin and boost collagen production.”
Source: SmallFlower

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl tripeptide-38, palmitoyl tripeptide-5

Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Ribes nigrum seed oilKey active· EmollientEffect: HighAn emollient. Can be helpful for restoring skin barrier function.~1.6–2%
SphingolipidsKey active· EmollientEffect: HighSphingolipids are a group of lipids with a common chemical structure. Some of them are naturally present in skin and can be converted to ceramides~0.25–0.45%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2.3–2.8%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.25–0.45%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.1–3.7%
Cassia angustifolia seed polysaccharideKey activeEffect: HighHelps attract water to the upper layer of the skin. Is sometimes referred to as "natural" hyaluronic acid (even though hyaluronic acid is not unnatural and is present in human skin)~0.2–0.35%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–4.7%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~5.7–7%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.4%
Mangifera indica seed butterKey activeEffect: HighHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.8–1.15%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
MelKey active· Humectant, EmollientEffect: MediumHelps to soften the upper layer of the skin and attract water to it~0.25–0.45%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.2–0.4%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.4–1.8%
Elaeis guineensis oilKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.25–0.45%
Hydrolyzed rice proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~0.35–0.6%
HoneyKey active· HumectantEffect: MediumHelps attract water to the skin and might have some anti-bacterial properties. Can be an allergen~0.2–0.35%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
Rosa damascena flower oilEffect: LowUsed as a fragrance. Can be irritating~0.2–0.35%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~0.25–0.45%
Rosa canina fruit oilUnder-dosedEffect: HighA great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritating~0.55–0.85%
Simmondsia chinensis seed oilUnder-dosedEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.45–0.7%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Anti-aging
Palmitoyl tripeptide-5, Palmitoyl tripeptide-38 + 5 more
Moderate evidence
What the product description says
“Strengthen Multi-peptide and nutrient-rich cream enriched with 4 powerful anti-aging peptides that help strengthen skin and boost collagen production.”
Source: SmallFlower

This product contains astaxanthin, palmitoyl tripeptide-38, palmitoyl tripeptide-5, tocotrienols. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
AstaxanthinKey activeEffect: MediumHelps neutralize free radicals in skin and might help to calm down inflammation~0.25–0.4%
TocotrienolsKey activeEffect: MediumA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.25–0.45%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Evens skin tone
GLUCOSAMINE HCL, PISUM SATIVUM EXTRACT
Weak evidence
What the product description says
“This luxuriously rich moisturizing cream aids in reducing the appearance of wrinkles and helps to restore tone and texture. . Vegetarian + cruelty-free .”
Source: SmallFlower

Effective ingredients missing or their concentration is too low

GLUCOSAMINE HCLKey activeEffect: Medium—
PISUM SATIVUM EXTRACTEffect: Low, below effective dose—
Anti-oxidation
Not advertised by the brand · Astaxanthin, Camellia oleifera leaf extract + 7 more
Strong evidence

This product contains antioxidants (astaxanthin, camellia oleifera leaf extract, tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

AstaxanthinKey activeEffect: HighHelps neutralize free radicals in skin and might help to calm down inflammation~0.25–0.4%
Camellia oleifera leaf extractKey activeEffect: HighA plant extract that can help neutralize free radicals and reduce inflammation, even though it is not usually used in sufficient concentration in cosmetics~0.2–0.35%
TocotrienolsKey activeEffect: HighA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.25–0.45%
Mangifera indica seed butterEffect: LowHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.8–1.15%
Hydrolyzed rice proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~0.35–0.6%
Ribes nigrum seed oilEffect: LowAn emollient. Can be helpful for restoring skin barrier function.~1.6–2%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Rosa canina fruit oilEffect: Low, below effective doseA great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritating~0.55–0.85%

Can it cause trouble?

Irritancy
10 strong irritants: Rosa damascena extract, Lavandula angustifolia oil + 8 more — patch-test recommended
High risk
We flagged 24 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosa damascena extractOil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.High~0.25–0.45%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.2–0.35%est.
Cananga odorata flower oilAn essential oil. Can be irritatingHigh~0.2–0.35%est.
Boswellia carterii oilUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.
Citrus aurantium dulcis peel oilAn essentil oil from orange peel. Potential allergen and can be irritatingHigh~0.2–0.35%est.
Citrus aurantium dulcis flower oil—High~0.2–0.35%est.
Rosa damascena flower oilUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.
Hamamelis virginiana waterA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~0.2–0.35%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.15–0.25%est.
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~0.15–0.25%est.
Phenethyl alcoholA fragrance. Can be irritatingHigh~0.1–0.15%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.1–3.7%est.
Ribes nigrum seed oilAn emollient. Can be helpful for restoring skin barrier function.Medium~1.6–2%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.65–0.95%est.
Rosa canina fruit oilA great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritatingMedium~0.55–0.85%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.45–0.7%est.
Cassia angustifolia seed polysaccharideHelps attract water to the upper layer of the skin. Is sometimes referred to as "natural" hyaluronic acid (even though hyaluronic acid is not unnatural and is present in human skin)Medium~0.2–0.35%est.
AstaxanthinHelps neutralize free radicals in skin and might help to calm down inflammationMedium~0.25–0.4%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.
Trisodium ethylenediamine disuccinateUsed to improve stability of the formulationMedium~0.2–0.4%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~0.25–0.45%est.
Potassium sorbateA preservativeMedium~0.15–0.3%est.
Acacia senegal gumHelps mask the small of other ingredients and improve the product textureMedium~0.15–0.3%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.2–1.5%est.
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.25–0.45%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.4–1.8%est.
Edit
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Helianthus annuus seed oil~5.7–7%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Glycerin~3.9–4.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Caprylic/capric triglyceride~3.1–3.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Squalane~2.3–2.8%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Cetearyl olivate~1.8–2.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Ribes nigrum seed oil~1.6–2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

An emollient. Can be helpful for restoring skin barrier function.

More about Ribes nigrum seed oil
Cetearyl alcohol~1.4–1.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Butyrospermum parkii butter~1.2–1.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Mangifera indica seed butter~0.8–1.15%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Helps to soften the upper layer of the skin and might have some anti-oxidant effect

More about Mangifera indica seed butter
Polysorbate 60~0.65–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Rosa canina fruit oil~0.55–0.85%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritating

More about Rosa canina fruit oil
C18-36 acid triglyceride~0.5–0.75%
Formula
Irritation risk
Low
More about C18-36 acid triglyceride
Sorbitan olivate~0.45–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Simmondsia chinensis seed oil~0.45–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Hydrolyzed rice protein~0.35–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Helps attract water to the upper layer of the skin. Might have some anti-oxidant properties

More about Hydrolyzed rice protein
Palmitoyl tripeptide-5~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Palmitoyl tripeptide-38~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38
Crocus chrysanthus bulb extract~0.25–0.5%
Formula
Irritation risk
Low
More about Crocus chrysanthus bulb extract
Rosa damascena extract~0.25–0.45%
Irritant · high
Irritation risk
High

Oil of a very fragrant pink rose used as fragrance in cosmetics. Extensive research has shown it has mixed benefits. In the pro column, inhaling this flower’s scent seems to have relaxing properties and the plant’s petals contain skin-soothing and antioxidant compounds that can benefit skin. On the flipside, the numerous chemicals that create this rose’s distinctive fragrance pose a risk of causing skin aggravation.

More about Rosa damascena extract
Tocotrienols~0.25–0.45%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms

More about Tocotrienols
Tocopherol~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryMoisturizingAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Hyaluronic acid~0.2–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Butyrospermum parkii butter~0.25–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Camellia oleifera leaf extract~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatory

A plant extract that can help neutralize free radicals and reduce inflammation, even though it is not usually used in sufficient concentration in cosmetics

More about Camellia oleifera leaf extract
Elaeis guineensis oil~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil
Cassia angustifolia seed polysaccharide~0.2–0.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is sometimes referred to as "natural" hyaluronic acid (even though hyaluronic acid is not unnatural and is present in human skin)

More about Cassia angustifolia seed polysaccharide
Polygonum cuspidatum extract~0.2–0.4%
Formula
Irritation risk
Low
More about Polygonum cuspidatum extract
Phospholipids~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Honey~0.2–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingAntibacterial

Helps attract water to the skin and might have some anti-bacterial properties. Can be an allergen

More about Honey
Mel~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and attract water to it

More about Mel
Sphingolipids~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Sphingolipids are a group of lipids with a common chemical structure. Some of them are naturally present in skin and can be converted to ceramides

More about Sphingolipids
Glucosamine~0.2–0.4%
Formula
Irritation risk
Low
More about Glucosamine
Hci (d)
Not recognized
Totarol~0.25–0.45%
Formula
Irritation risk
Low
More about Totarol
Lavandula angustifolia oil~0.2–0.35%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Cananga odorata flower oil~0.2–0.35%
Irritant · high
Irritation risk
High

An essential oil. Can be irritating

More about Cananga odorata flower oil
Boswellia carterii oil~0.2–0.35%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Boswellia carterii oil
Citrus aurantium dulcis peel oil~0.2–0.35%
Irritant · high
Irritation risk
High

An essentil oil from orange peel. Potential allergen and can be irritating

More about Citrus aurantium dulcis peel oil
Citrus aurantium dulcis flower oil~0.2–0.35%
Irritant · high
Irritation risk
High
More about Citrus aurantium dulcis flower oil
Rosa damascena flower oil~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Used as a fragrance. Can be irritating

More about Rosa damascena flower oil
Jasminum officinale oil~0.15–0.3%
Formula
Irritation risk
Low
More about Jasminum officinale oil
Astaxanthin~0.25–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-agingAnti-inflammatory

Helps neutralize free radicals in skin and might help to calm down inflammation

More about Astaxanthin
Hamamelis virginiana water~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana water
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Trisodium ethylenediamine disuccinate~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Used to improve stability of the formulation

More about Trisodium ethylenediamine disuccinate
Citric acid~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Hydroxypropyl cyclodextrin~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
Polysorbate 20~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Potassium sorbate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Acacia senegal gum~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Helps mask the small of other ingredients and improve the product texture

More about Acacia senegal gum
Xanthan gum~0.15–0.25%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Alcohol~0.15–0.25%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Alcohol denat.~0.15–0.25%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Phenethyl alcohol~0.1–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Phenethyl alcohol
Ingredient list view

Water, Helianthus annuus seed oil, Glycerin, Caprylic/capric triglyceride, Squalane, Cetearyl olivate, Ribes nigrum seed oil, Cetearyl alcohol, Butyrospermum parkii butter, Mangifera indica seed butter, Polysorbate 60, Rosa canina fruit oil, C18-36 acid triglyceride, Sorbitan olivate, Simmondsia chinensis seed oil, Hydrolyzed rice protein, Palmitoyl tripeptide-5, Palmitoyl tripeptide-38, Crocus chrysanthus bulb extract, Rosa damascena extract, Tocotrienols, Tocopherol, Hyaluronic acid, Butyrospermum parkii butter, Camellia oleifera leaf extract, Elaeis guineensis oil, Cassia angustifolia seed polysaccharide, Polygonum cuspidatum extract, Phospholipids, Honey, Mel, Sphingolipids, Glucosamine, Unknown, Totarol, Lavandula angustifolia oil, Cananga odorata flower oil, Boswellia carterii oil, Citrus aurantium dulcis peel oil, Citrus aurantium dulcis flower oil, Rosa damascena flower oil, Jasminum officinale oil, Astaxanthin, Hamamelis virginiana water, Caprylyl glycol, Trisodium ethylenediamine disuccinate, Citric acid, Hydroxypropyl cyclodextrin, Polysorbate 20, Potassium sorbate, Acacia senegal gum, Xanthan gum, Alcohol, Alcohol denat., Phenethyl alcohol

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Amazon USPrice as of 10/20/2026 15:08 GMT
$33.94
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SmallFlower
$56.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MyChelle DermaceuticalsSupreme Polypeptide CreamYOUR PRODUCTAllies of SkinMulti Nutrient & Dioic Renewing CreamHoliFrogGrand Amino Cushion CreamThrive CausemeticsTimeless Ambition™ Power 7-Peptide Firming Moisturizer
Match—60%58%55%
Price$33.94$55.00+$21.06$60.00+$26.06$49.00+$15.06
Shared key ingredients—8 of 187 of 186 of 18
Key difference—Ferulic AcidNiacinamideGluconolactone
Irritancy High Medium Medium Medium
Drying alcohol Contains drying alcohol ———
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Product summary

"MyChelle Dermaceuticals - Supreme Polypeptide Cream" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. MyChelle Dermaceuticals - Supreme Polypeptide Cream ticks this box. Glycerin, hyaluronic acid, honey, hydrolyzed rice protein and mel in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ribes nigrum seed oil, sphingolipids, butyrospermum parkii butter, caprylic/capric triglyceride and helianthus annuus seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moistruizer also contains peptides (palmitoyl tripeptide-5 0.30% - 0.60% and palmitoyl tripeptide-38 0.30% - 0.55%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "MyChelle Dermaceuticals" is cruelty free and so is its parent company.

Price

The product retails for 132.67A$ in Australia and from 45.61$ up to 56.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 30 studies and safety reviews.

  1. 1
    Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
  2. 2
    Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
  3. 3
    Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
  4. 4
    Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
  5. 5
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  6. 6
    Extraction and Characteristics of Seed Kernel Oil from Mangopdfs.semanticscholar.org
MyChelle Dermaceuticals Supreme Polypeptide Cream
MyChelle DermaceuticalsSupreme Polypeptide Cream
Buy on Amazon$33.94 · as of 10/20 15:08 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$33.94 · as of 10/20 15:08 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.