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Mesoestetic Radiance DNA Essence
Mesoestetic

Mesoestetic Radiance DNA Essence

Efficacy75/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Retinyl palmitate, Serine + 2 more
May help
What the product description says
“The active ingredient elastin, helps to encourage collagen production and boost elasticity, providing a tightening and anti-ageing effect.”
Source: Face the future

This product contains retinyl palmitate, serine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.3–0.55%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.5%
Nicotiana sylvestris leaf cell cultureEffect: LowHas been claimed to have an ability to protect collagen and stimulate its production in skin but further research is lacking so far~0.55–0.85%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%
Moisturizing
Side benefit the brand mentions · Urea, Glycerin + 15 more
Works well
What the product description says
“Radiance DNA Essence”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: urea

UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.25–0.45%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.4–5.4%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~4.2–5.1%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~3.1–3.8%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.4–3%
PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1.9–2.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~1.3–1.6%
Soluble collagenKey active· HumectantEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.65–0.95%
Nicotiana sylvestris leaf cell cultureKey active· EmollientEffect: MediumHas been claimed to have an ability to protect collagen and stimulate its production in skin but further research is lacking so far~0.55–0.85%
Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.25–0.45%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.5%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%
Lecithin· EmollientEffect: LowUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~1.6–2%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~1–1.2%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.3–0.55%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.25%
Evens skin tone
Side benefit · Retinyl palmitate, Lactic acid
May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: retinyl palmitate.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.3–0.55%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%

Can it cause trouble?

Irritancy
2 strong irritants: Retinyl palmitate, Parfum
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.3–0.55%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.2%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~1.3–1.6%est.
Nicotiana sylvestris leaf cell cultureHas been claimed to have an ability to protect collagen and stimulate its production in skin but further research is lacking so farMedium~0.55–0.85%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.5–0.75%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.45–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.45–0.7%est.
BhaHelps preserve the product formulationMedium~0.45–0.65%est.
BhtA preservativeMedium~0.4–0.6%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.5%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.25–0.45%est.
Sorbic acidA preservativeMedium~0.1–0.2%est.
EthylhexylglycerinA preservativeMedium~0.05–0.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
Alternatives
Cheaper, or higher on efficacy
Superdrug Simply Pure Hydrating Night Serum
Simply Pure Superdrug Simply Pure Hydrating Night Serum
CheaperHigher efficacy · 100/10055% match
$5.33
Hydro Boost Ultra Hydrating Serum with Hyaluronic Acid
Neutrogena Hydro Boost Ultra Hydrating Serum with Hyaluronic Acid
Cheaper53% match
$15.08
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.4–5.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
C12-15 alkyl benzoate~4.2–5.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Cyclopentasiloxane~3.1–3.8%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Dimethicone~2.4–3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Polymethylsilsesquioxane~1.9–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane
Lecithin~1.6–2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Hydrolyzed soy flour~1.5–1.8%
Formula
Irritation risk
Low
More about Hydrolyzed soy flour
Caprylic/capric triglyceride~1.3–1.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glyceryl stearate citrate~1–1.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Hydrolyzed elastin~0.75–1.1%
Formula
Irritation risk
Low
More about Hydrolyzed elastin
Soluble collagen~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Soluble collagen
Nicotiana sylvestris leaf cell culture~0.55–0.85%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-aging

Has been claimed to have an ability to protect collagen and stimulate its production in skin but further research is lacking so far

More about Nicotiana sylvestris leaf cell culture
Tocopheryl acetate~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Sodium acrylates copolymer~0.45–0.65%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Disodium edta~0.45–0.7%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Bha~0.45–0.65%
Irritant · medium
Irritation risk
Medium

Helps preserve the product formulation

More about Bha
Bht~0.4–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Retinyl palmitate~0.3–0.55%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-agingAnti-blemishEvens skin toneExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Sorbitol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Lactic acid~0.25–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Serine~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Sodium lactate~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Tea-lactate~0.25–0.45%
Formula
Irritation risk
Low
More about Tea-lactate
Urea~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Sodium hyaluronate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Methylsilanol mannuronate~0.2–0.35%
Formula
Irritation risk
Low
More about Methylsilanol mannuronate
Sodium chloride~0.2–0.35%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Allantoin~0.1–0.25%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Parfum~0.1–0.2%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sorbic acid~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Phenoxyethanol~0.1–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Glycerin, C12-15 alkyl benzoate, Cyclopentasiloxane, Dimethicone, Polymethylsilsesquioxane, Lecithin, Hydrolyzed soy flour, Caprylic/capric triglyceride, Glyceryl stearate citrate, Hydrolyzed elastin, Soluble collagen, Nicotiana sylvestris leaf cell culture, Tocopheryl acetate, Sodium acrylates copolymer, Disodium edta, Bha, Bht, Retinyl palmitate, Sorbitol, Lactic acid, Serine, Sodium lactate, Tea-lactate, Urea, Sodium hyaluronate, Methylsilanol mannuronate, Sodium chloride, Allantoin, Parfum, Sorbic acid, Phenoxyethanol, Ethylhexylglycerin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MesoesteticRadiance DNA EssenceYOUR PRODUCTSimply PureSuperdrug Simply Pure Hydrating Night SerumNeutrogenaHydro Boost Ultra Hydrating Serum with Hyaluronic AcidElizabeth GrantCaviar Cellular Recharge Super Serum
Match—55%53%50%
Price—$5.33$15.08—
Shared key ingredients—7 of 126 of 128 of 12
Key difference—DimethiconolAllantoinPanthenol
Irritancy Medium Low Low Medium
Drying alcohol————
View product Shop Shop Shop
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Product summary

"Mesoestetic - Radiance DNA Essence" is effective for: Anti-inflammatory and Moisturizing

This moisturizer could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • this moisturizer includes a form of Retinoids (vitamin A) - retinyl palmitate 0.30% - 0.55%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.

Price

The product retails from 59.99£ up to 76.00£ in the United Kingdom and for 156.50A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Final Report on the Safety Assessment of Acrylates Copolymer and 33 Related Cosmetic Ingredientsjournals.sagepub.com
  5. 5
    Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
  6. 6
    Dual Effects of Alpha-Hydroxy Acids on the Skinpdfs.semanticscholar.org
Mesoestetic Radiance DNA Essence
MesoesteticRadiance DNA Essence
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As an Amazon Associate, WIMJ earns from qualifying purchases.