Meditime

Meditime Dermazium Cream

Name: Meditime - Dermazium Cream
Brand: Meditime

Efficacy100/100IrritancyHigh

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Works for

2 of 2 advertised claims delivered

Anti-aging

13 ingredients credited for this claim

Strong support

What the product description says

“Contains rich active ingredients without being diluted with water to provide bio anti-aging properties.”

Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, asiaticoside, madecassoside, resveratrol, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-2.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–1.9%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.4–0.65%

AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.35–0.6%

Sh-polypeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Sh-polypeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.4–0.6%

ResveratrolKey activeEffect: MediumHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone~0.4–0.6%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Sh-oligopeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.8–3.4%

Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.7%

3-o-ethyl ascorbic acidEffect: Low, below effective doseA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.45–0.65%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.45–0.65%

Moisturizing

39 ingredients credited for this claim

Strong support

What the product description says

“This is an eye cream enriched with over 60% Botalium to offer moisturizing and lifting effects to your skin.”

Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: anhydroxylitol, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, madecassoside, niacinamide, panthenol, sh-oligopeptide-2, sh-polypeptide-1

XylitylglucosideKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrier function~0.4–0.6%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.4–0.6%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~4.6–5.6%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.45–0.65%

Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.55–0.85%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.8–3.4%

Kappaphycus alvarezii extractKey activeEffect: HighA red algae extract that can help attract water to the upper layer of the skin and might have some antioxidant properties~0.45–0.65%

AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.35–0.6%

MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.4–0.6%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–1.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.3–4%

Oryza sativa bran oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and might have some anti-oxidant properties~0.5–0.75%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.4–0.65%

AnhydroxylitolKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrir function~0.45–0.65%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.55–0.8%

Sh-oligopeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%

Sh-polypeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Sh-polypeptide-2Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.45–0.65%

Hydrogenated poly(c6-14 olefin)Key active· EmollientEffect: MediumHelps soften the upper layer of the skin and create a nice product texture~2.1–2.5%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.5–0.75%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.4–0.65%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.55–0.85%

Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~0.6–0.95%

Scutellaria baicalensis root extract· HumectantEffect: LowA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties~0.3–0.55%

Phytosteryl/isostearyl/cetyl/stearyl/behenyl dimer dilinoleate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~1.4–1.7%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.5–0.8%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.45–0.7%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.95–1.2%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~5.2–6.4%

Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.5–0.75%

AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Argania spinosa kernel oilUnder-dosedEffect: HighAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.5–0.75%

Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.7–1%

Centella asiatica extractUnder-dosedEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.7%

Simmondsia chinensis seed oilUnder-dosedEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.55–0.8%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.55–0.8%

Evens skin tone

Not advertised by the brand · 7 ingredients credited for this claim

Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract, madecassoside, resveratrol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.4–0.6%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.4–0.6%

ResveratrolEffect: LowHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone~0.4–0.6%

3-o-ethyl ascorbic acidUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.45–0.65%

Anti-blemish

Not advertised by the brand · 5 ingredients credited for this claim

Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Rosmarinus officinalis leaf extractUnder-dosedEffect: MediumCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.4–0.6%

Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.45–0.7%

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Anti-oxidation

Not advertised by the brand · 16 ingredients credited for this claim

Strong support

This product contains antioxidants (asiaticoside, glutathione, madecassoside, resveratrol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - haematococcus pluvialis extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

ResveratrolKey activeEffect: HighHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone~0.4–0.6%

MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.4–0.6%

Haematococcus pluvialis extractKey activeEffect: MediumGreen algae extract that might contain antioxidant astaxanthin~25–31%

Scutellaria baicalensis root extractEffect: LowA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties~0.3–0.55%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.4–0.65%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.4–0.6%

Kappaphycus alvarezii extractEffect: LowA red algae extract that can help attract water to the upper layer of the skin and might have some antioxidant properties~0.45–0.65%

Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.45–0.65%

Polygonum cuspidatum root extractEffect: Low, below effective doseA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product~0.45–0.65%

Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.4–0.6%

Argania spinosa kernel oilEffect: Low, below effective doseAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.5–0.75%

Can it cause trouble?

Irritancy

3 strong irritants: Illicium verum fruit extract, Cananga odorata flower oil + 1 more — patch-test recommended

High risk

We flagged 24 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Illicium verum fruit extractAnise fruit extract. Used as a fragrance. Can be irritatingHigh~0.35–0.65%est.

Scutellaria baicalensis root extractA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant propertiesHigh~0.3–0.55%est.

Cananga odorata flower oilAn essential oil. Can be irritatingHigh~0.4–0.6%est.

3-o-ethyl ascorbic acidA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsHigh~0.45–0.65%est.

Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.4–0.6%est.

Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.45–0.65%est.

Haematococcus pluvialis extractGreen algae extract that might contain antioxidant astaxanthinMedium~25–31%est.

1,2-hexanediolA preservativeMedium~0.9–1.1%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.7–1%est.

Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.5–0.75%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.5–0.75%est.

Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.55–0.8%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.45–0.7%est.

Polygonum cuspidatum root extractA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the productMedium~0.45–0.65%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.45–0.65%est.

Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.4–0.6%est.

AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.35–0.6%est.

Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.5–0.75%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.5–0.8%est.

MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.4–0.6%est.

ResveratrolHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin toneMedium~0.4–0.6%est.

EthylhexylglycerinA preservativeMedium~0.3–0.5%est.

Swertia chirata extractA plant extract that can have an anti-bacterial and anti-inflammatory effect, but evidence of effectiveness is lackingMedium~0.2–0.4%est.

PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.25–0.45%est.

Comedogenic

5 ingredients rated 2 or more on the 0–5 pore-clogging scale

5 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Ecklonia cava extract—3/5~4.9–6%est.

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2.8–3.4%est.

Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.5–0.75%est.

Fucus vesiculosus extract—3/5~0.45–0.7%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.55–0.85%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Haematococcus pluvialis extract~25–31%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

Green algae extract that might contain antioxidant astaxanthin

More about Haematococcus pluvialis extract

Ecklonia cava extract~4.9–6%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Ecklonia cava extract

Butylene glycol~5.2–6.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Squalane~4.6–5.6%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Glycerin~3.3–4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Butyrospermum parkii butter~2.8–3.4%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Hydrogenated poly(c6-14 olefin)~2.1–2.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Hydrogenated poly(c6-14 olefin)

Niacinamide~1.6–1.9%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Phytosteryl/isostearyl/cetyl/stearyl/behenyl dimer dilinoleate~1.4–1.7%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Phytosteryl/isostearyl/cetyl/stearyl/behenyl dimer dilinoleate

1,2-hexanediol~0.9–1.1%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Glyceryl stearate~0.95–1.2%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Cetearyl olivate~0.7–1.05%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Cetearyl olivate

Glycereth-26~0.6–0.9%

Formula

Irritation risk: Low

Helps create a thicker product consistency

More about Glycereth-26

Caprylic/capric triglyceride~0.7–1%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Coco-caprylate/caprate~0.6–0.95%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate

Panthenol~0.55–0.8%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Sorbitan olivate~0.55–0.8%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan olivate

Deinococcus ferment extract filtrate~0.5–0.75%

Formula

Irritation risk: Low

More about Deinococcus ferment extract filtrate

Cetearyl alcohol~0.55–0.85%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Polyacrylate-13~0.55–0.85%

Formula

Irritation risk: Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13

Arginine~0.4–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Carbomer~0.45–0.65%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Water~0.4–0.65%

Formula

Irritation risk: Low

Plain old water

More about Water

Illicium verum fruit extract~0.35–0.65%

Irritant · high

Irritation risk: High

Anise fruit extract. Used as a fragrance. Can be irritating

More about Illicium verum fruit extract

Jasminum officinale oil~0.3–0.55%

Formula

Irritation risk: Low

More about Jasminum officinale oil

Polyisobutene~0.5–0.75%

Formula

Irritation risk: Low

Used to improve the product consistency

More about Polyisobutene

Sodium hyaluronate~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Allantoin~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Hydrolyzed collagen~0.55–0.85%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen

Scutellaria baicalensis root extract~0.3–0.55%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatoryAnti-oxidationMoisturizingReduces irritationAntibacterial

A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties

More about Scutellaria baicalensis root extract

Adenosine~0.4–0.65%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Xylitylglucoside~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitylglucoside

Anhydroxylitol~0.45–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrir function

More about Anhydroxylitol

Polysorbate 20~0.45–0.7%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Sorbitan isostearate~0.45–0.7%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Xylitol~0.4–0.65%

Formula

Irritation risk: Low

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitol

Camellia japonica seed oil~0.5–0.75%

Formula

Irritation risk: Low

A plant oil that helps to soften the upper layer of the skin and can help restore skin's barrier function. Might have an anti-oxidant effect

More about Camellia japonica seed oil

Oryza sativa bran oil~0.5–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and might have some anti-oxidant properties

More about Oryza sativa bran oil

Argania spinosa kernel oil~0.5–0.75%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil

Olea europaea fruit oil~0.5–0.75%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Cananga odorata flower oil~0.4–0.6%

Irritant · high

Irritation risk: High

An essential oil. Can be irritating

More about Cananga odorata flower oil

Simmondsia chinensis seed oil~0.55–0.8%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil

Centella asiatica extract~0.45–0.7%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-inflammatoryReduces rednessReduces irritationAnti-oxidationAnti-agingAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Propanediol~0.45–0.7%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Glucose~0.45–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Polygonum cuspidatum root extract~0.45–0.65%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product

More about Polygonum cuspidatum root extract

Sodium chloride~0.5–0.75%

Formula

Irritation risk: Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride

3-o-ethyl ascorbic acid~0.45–0.65%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-oxidationAnti-aging

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about 3-o-ethyl ascorbic acid

Glutathione~0.45–0.65%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingEvens skin tone

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Camellia sinensis leaf extract~0.45–0.65%

Under-dosed

Irritation risk: Low

Works for

AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Glycyrrhiza glabra root extract~0.4–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Reduces rednessEvens skin toneAnti-oxidationAnti-inflammatoryAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract

Asiaticoside~0.35–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside

Isopropyl palmitate~0.5–0.75%

Comedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate

Caesalpinia spinosa fruit extract~0.45–0.65%

Formula

Irritation risk: Low

More about Caesalpinia spinosa fruit extract

Rosmarinus officinalis leaf extract~0.4–0.6%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract

Chamomilla recutita flower extract~0.45–0.65%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract

Acmella oleracea extract~0.45–0.65%

Formula

Irritation risk: Low

More about Acmella oleracea extract

Pentylene glycol~0.5–0.8%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Disodium phosphate~0.45–0.65%

Formula

Irritation risk: Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate

Dextrin~0.45–0.7%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Kappaphycus alvarezii extract~0.45–0.65%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

A red algae extract that can help attract water to the upper layer of the skin and might have some antioxidant properties

More about Kappaphycus alvarezii extract

Lecithin~0.55–0.8%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Biosaccharide gum-4~0.45–0.65%

Formula

Irritation risk: Low

Helps improve the product texture

More about Biosaccharide gum-4

Madecassoside~0.4–0.6%

Hero · MoisturizingIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside

Sodium phosphate~0.45–0.65%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Sodium phosphate

Prunella vulgaris extract~0.4–0.6%

Formula

Irritation risk: Low

More about Prunella vulgaris extract

Resveratrol~0.4–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-agingEvens skin tone

Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone

More about Resveratrol

Fucus vesiculosus extract~0.45–0.7%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Fucus vesiculosus extract

Sr-(oligopeptide-91 clostridium botulinum polypeptide-1)~0.3–0.6%

Formula

Irritation risk: Low

More about Sr-(oligopeptide-91 clostridium botulinum polypeptide-1)

Ethylhexylglycerin~0.3–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Swertia chirata extract~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

AntibacterialAnti-inflammatory

A plant extract that can have an anti-bacterial and anti-inflammatory effect, but evidence of effectiveness is lacking

More about Swertia chirata extract

Phosphatidylcholine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine

Acetyl hexapeptide-8~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Sh-oligopeptide-2~0.2–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-2

Sh-polypeptide-1~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-1

Sh-polypeptide-2~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-2

Ingredient list view

Haematococcus pluvialis extract, Ecklonia cava extract, Butylene glycol, Squalane, Glycerin, Butyrospermum parkii butter, Hydrogenated poly(c6-14 olefin), Niacinamide, Phytosteryl/isostearyl/cetyl/stearyl/behenyl dimer dilinoleate, 1,2-hexanediol, Glyceryl stearate, Cetearyl olivate, Glycereth-26, Caprylic/capric triglyceride, Coco-caprylate/caprate, Panthenol, Sorbitan olivate, Deinococcus ferment extract filtrate, Cetearyl alcohol, Polyacrylate-13, Arginine, Carbomer, Water, Illicium verum fruit extract, Jasminum officinale oil, Polyisobutene, Sodium hyaluronate, Allantoin, Hydrolyzed collagen, Scutellaria baicalensis root extract, Adenosine, Xylitylglucoside, Anhydroxylitol, Polysorbate 20, Sorbitan isostearate, Xylitol, Camellia japonica seed oil, Oryza sativa bran oil, Argania spinosa kernel oil, Olea europaea fruit oil, Cananga odorata flower oil, Simmondsia chinensis seed oil, Centella asiatica extract, Propanediol, Glucose, Polygonum cuspidatum root extract, Sodium chloride, 3-o-ethyl ascorbic acid, Glutathione, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Asiaticoside, Isopropyl palmitate, Caesalpinia spinosa fruit extract, Rosmarinus officinalis leaf extract, Chamomilla recutita flower extract, Acmella oleracea extract, Pentylene glycol, Disodium phosphate, Dextrin, Kappaphycus alvarezii extract, Lecithin, Biosaccharide gum-4, Madecassoside, Sodium phosphate, Prunella vulgaris extract, Resveratrol, Fucus vesiculosus extract, Sr-(oligopeptide-91 clostridium botulinum polypeptide-1), Ethylhexylglycerin, Swertia chirata extract, Phosphatidylcholine, Acetyl hexapeptide-8, Sh-oligopeptide-2, Sh-polypeptide-1, Sh-polypeptide-2

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MeditimeDermazium CreamYOUR PRODUCT	TOSOWOONGCentella Asiatica Leaf Water Cream	NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream	DERMAFIRMAge Reviving Firming Cream A4
Match	—	78%	76%	75%
Price	$18.90	$16.36−$2.54	$39.59+$20.69	$23.80+$4.90
Shared key ingredients	—	14 of 30	13 of 30	12 of 30
Key difference	—	Copper Tripeptide-1	Copper Tripeptide-1	Oligopeptide-1
Irritancy	High	High	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Meditime - Dermazium Cream" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Meditime - Dermazium Cream ticks this box. Acetyl hexapeptide-8, panthenol, anhydroxylitol, arginine and glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (hydrolyzed collagen, oryza sativa bran oil, arginine, butyrospermum parkii butter and squalane) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

We like that this moisturizer contains peptides (sh-polypeptide-1 0.15% - 0.30%, sh-oligopeptide-2 0.20% - 0.40% and acetyl hexapeptide-8 0.20% - 0.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.40% - 0.65%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - madecassoside 0.40% - 0.60% and asiaticoside 0.35% - 0.60% The Centella Asiatica Actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
An effective concentration of Panthenol (pro-vitamin B5) - about 0.55% - 0.80%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: lecithin, jojoba oil, agran oil, allantoin and caprylic/capric triglyceride

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.