Medik8 Eye Peptides Cream

Medik8 Eye Peptides Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Anti-aging
Palmitoyl hexapeptide-12, Palmitoyl tetrapeptide-7 + 5 more
Strong evidence
What the product description says
“Key Benefits Multi-peptide complex Improves the look of skin firmness Supports visibly brighter under-eyes Skin texture around the eye area appears smoother UK200030348”
Source: SpaceNK US

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: dipeptide-2, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Dipeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.6%
ChrysinEffect: LowMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.15–0.3%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Moisturizing
Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 + 11 more
Strong evidence
What the product description says
“The under eye area is lifted, moisturised and brighter.”
Source: SpaceNK US

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glycine soja protein.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: ceramide ng, palmitoyl tetrapeptide-7.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ng, dipeptide-2, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.25–0.5%
Ceramide ngHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.5–0.75%
Dipeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–5.3%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Hydrolyzed rice proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~1.5–1.9%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~3.1–3.8%
Glycine soja proteinKey active· Humectant, EmollientEffect: MediumA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.6%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~2–2.4%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.1–1.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Anti-oxidation
Not advertised by the brand · Superoxide dismutase, Chrysin + 4 more
Strong evidence

This product contains antioxidants (superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - chrysin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.25–0.5%
ChrysinKey activeEffect: MediumMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.15–0.3%
Hesperidin methyl chalconeEffect: LowMight help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation~0.6–0.85%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.6%
Hydrolyzed rice proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-oxidant properties~1.5–1.9%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Evens skin tone
Not advertised by the brand · Chrysin, Glycine soja protein + 1 more
Moderate evidence

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: chrysin, glycine soja protein.

ChrysinKey activeEffect: MediumMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin~0.15–0.3%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.6%
N-hydroxysuccinimideEffect: LowIs claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating~0.1–0.15%

Can it cause trouble?

Irritancy
1 strong irritant: Alcohol denat.
Medium risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~8.2–10.1%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.65–1%est.
Hesperidin methyl chalconeMight help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritationHigh~0.6–0.85%est.
N-hydroxysuccinimideIs claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritatingHigh~0.1–0.15%est.
Steareth-20Helps oil and water mix togetherMedium~0.95–1.2%est.
Peg-10 phytosterolHelps oil and water mix togetherMedium~0.45–0.65%est.
Dehydroacetic acidA preservativeMedium~0.3–0.55%est.
Benzoic acidA preservativeMedium~0.25–0.5%est.
Sorbic acidA preservativeMedium~0.2–0.4%est.
ChrysinMight be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skinMedium~0.15–0.3%est.
Potassium sorbateA preservativeMedium~0.1–0.2%est.
Chlorhexidine digluconateA preservativeMedium~0.1–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Alcohol denat.~8.2–10.1%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Glycerin~4.3–5.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
C12-15 alkyl benzoate~3.1–3.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Xanthan gum~2.2–2.7%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Tribehenin~2–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Hydrolyzed rice protein~1.5–1.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Helps attract water to the upper layer of the skin. Might have some anti-oxidant properties

More about Hydrolyzed rice protein
Benzyl alcohol~0.65–1%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Butylene glycol~1.1–1.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Steareth-20~0.95–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-20
Hesperidin methyl chalcone~0.6–0.85%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Might help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation

More about Hesperidin methyl chalcone
Ceramide ng~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ng
Peg-10 phytosterol~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-10 phytosterol
Dehydroacetic acid~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Dehydroacetic acid
Glycine soja protein~0.3–0.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizingAnti-agingEvens skin toneAnti-oxidation

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

More about Glycine soja protein
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Superoxide dismutase~0.25–0.5%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-oxidation

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase
Phenoxyethanol~0.3–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Benzoic acid~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Benzoic acid
Sorbic acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Dipeptide-2~0.2–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide-2
Palmitoyl tetrapeptide-7~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Palmitoyl tripeptide-1~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl hexapeptide-12~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingMoisturizing

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Chrysin~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-oxidationAnti-aging

Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin

More about Chrysin
Carbomer~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Potassium sorbate~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Chlorhexidine digluconate~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorhexidine digluconate
Polysorbate 20~0.1–0.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
N-hydroxysuccinimide~0.1–0.15%
Irritant · high
Irritation risk
High
Works for
Evens skin tone

Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating

More about N-hydroxysuccinimide
Sodium dextran sulfate~0.05–0.1%
Formula
Tocopherol~0.05–0.1%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ingredient list view

Water, Alcohol denat., Glycerin, C12-15 alkyl benzoate, Xanthan gum, Tribehenin, Hydrolyzed rice protein, Benzyl alcohol, Butylene glycol, Steareth-20, Hesperidin methyl chalcone, Ceramide ng, Peg-10 phytosterol, Dehydroacetic acid, Glycine soja protein, Sodium benzoate, Superoxide dismutase, Phenoxyethanol, Benzoic acid, Sorbic acid, Dipeptide-2, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Palmitoyl hexapeptide-12, Chrysin, Carbomer, Potassium sorbate, Chlorhexidine digluconate, Polysorbate 20, N-hydroxysuccinimide, Sodium dextran sulfate, Tocopherol

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Amazon USPrice as of 10/29/2026 09:54 GMT
$55.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Medik8Eye Peptides CreamYOUR PRODUCTDr Dennis GrossC + Collagen Brighten + Firm Eye CreamKate SomervilleLine Release Under Eye Repair CreamN Ā E L IApple Stem Cell Eye Cream - Dark Circles, Puffiness & Wrinkle Corrector
Match—68%59%58%
Price$55.00$65.00+$10.00$159.94+$104.94$25.00−$30.00
Shared key ingredients—8 of 86 of 87 of 8
Key difference—NiacinamideSalicylic AcidPersea Gratissima Oil
Irritancy Medium Medium Medium Medium
Drying alcohol Contains drying alcohol ———
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Product summary

"Medik8 - Eye Peptides Cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Glycerin, glycine soja protein, hydrolyzed rice protein and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide ng, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, c12-15 alkyl benzoate and glycine soja protein in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (ceramide ng 0.50% - 0.75%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • We like that this moisturizer contains peptides (palmitoyl tripeptide-1 0.25% - 0.45%, palmitoyl tetrapeptide-7 0.25% - 0.45%, palmitoyl hexapeptide-12 0.20% - 0.35% and dipeptide-2 0.20% - 0.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Medik8" is cruelty free, but its parent company is not.

Price

The product retails for 52.00$ in the United States and for 61.30CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 22 studies and safety reviews.

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