MEDIHEAL

MEDIHEAL PDRN Lifting Serum

Name: MEDIHEAL - PDRN Lifting Serum
Brand: MEDIHEAL

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Anti-aging

Niacinamide, Adenosine + 3 more

Works well

What the product description says

“3-step pore aging care for pore elasticity improvement, pore reduction, and radiance.”

Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: oligopeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1–1.45%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.01–0.05%

Oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.01–0.1%

Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.01–0.1%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.2%

Anti-blemish

Niacinamide, Beta-glucan

Works well

What the product description says

“3-step pore aging care for pore elasticity improvement, pore reduction, and radiance.”

Source: Lila Beauty

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1–1.45%

Moisturizing

Side benefit · Niacinamide, Oligopeptide-1 + 19 more

Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, oligopeptide-1

Oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.01–0.1%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.9–4.3%

Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.9–1.35%

Saccharum officinarum extractKey activeEffect: HighSugar extract that helps attract water to the upper layer of the skin~0.45–1.05%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.6%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.1–0.4%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.05–0.1%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.05–0.2%

Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.01–0.1%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.01–0.05%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4.5–6.7%

Cetyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin and creates a thicker product texture~1.3–1.9%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.05–0.1%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.05–0.25%

Rosa damascena flower waterEffect: Low, below effective doseUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating~1.1–1.6%

PanthenolUnder-dosedHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.1–0.3%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.1–0.45%

Ceramide npUnder-dosedA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.05–0.25%

BetaineUnder-dosedHelps attract water to the upper layer of the skin and improves the product texture~0.05–0.25%

Evens skin tone

Side benefit · Niacinamide

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Can it cause trouble?

Irritancy

2 strong irritants: Rosa damascena flower water, Rose flower oil

Medium risk

We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Rosa damascena flower waterUsed to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritatingHigh~1.1–1.6%est.

Rose flower oilFlower oil that is used as a fragranceHigh~0.35–0.75%est.

Rose extractUsed as a fragrance. Can be irritatingHigh~0.1–0.35%est.

1,2-hexanediolA preservativeMedium~0.9–1.35%est.

Cetyl ethylhexanoateAn emollient that helps soften the skin and creates a thicker product textureMedium~1.3–1.9%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.1–0.45%est.

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.05–0.25%est.

Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.05–0.3%est.

Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.05–0.15%est.

EthylhexylglycerinA preservativeMedium~0.01–0.1%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.01–0.1%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.05–0.25%est.

Caprylyl/capryl glucosideHelps oil and water mix together. Can be used as a cleansing agentMedium~0.1–0.35%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.9–1.35%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.05–0.2%est.

Alternatives

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Medicube Glutathione Glow Serum

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%

Formula

Irritation risk: Low

Plain old water

More about Water

Butylene glycol~4.5–6.7%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Glycerin~2.9–4.3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Isopentyldiol~2.3–3.4%

Formula

Irritation risk: Low

Helps dissolve other ingredients in a formulation

More about Isopentyldiol

1,2-hexanediol~0.9–1.35%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Cetyl ethylhexanoate~1.3–1.9%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin and creates a thicker product texture

More about Cetyl ethylhexanoate

Niacinamide~1–1.45%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Rosa damascena flower water~1.1–1.6%

Irritant · high

Irritation risk: High

Works for

MoisturizingAnti-oxidation

Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating

More about Rosa damascena flower water

Chondrus crispus extract~0.9–1.35%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract

Saccharum officinarum extract~0.45–1.05%

Key active

Irritation risk: Low

Works for

Moisturizing

Sugar extract that helps attract water to the upper layer of the skin

More about Saccharum officinarum extract

Rose flower oil~0.35–0.75%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Flower oil that is used as a fragrance

More about Rose flower oil

Sodium hyaluronate~0.15–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Rose extract~0.1–0.35%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Rose extract

Caprylic/capric triglyceride~0.1–0.45%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Propanediol~0.1–0.35%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Squalane~0.1–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Betaine~0.05–0.25%

Under-dosed

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Panthenol~0.1–0.3%

Under-dosed

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Polyacrylate crosspolymer-6~0.1–0.3%

Formula

Irritation risk: Low

More about Polyacrylate crosspolymer-6

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.05–0.25%

Irritant · medium

Irritation risk: Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer

Sodium stearoyl glutamate~0.05–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate

Sodium polyacrylate~0.05–0.25%

Formula

Irritation risk: Low

Works for

Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate

Hydrogenated lecithin~0.05–0.15%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Cetearyl glucoside~0.05–0.15%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside

Ethylhexylglycerin~0.01–0.1%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Adenosine~0.01–0.05%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Citric acid~0.01–0.1%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Sorbitan isostearate~0.05–0.1%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Sodium phytate~0.05–0.15%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Dextrin~0.05–0.1%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Beta-glucan~0.01–0.1%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationAnti-agingAnti-blemishAnti-oxidation

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan

Dipropylene glycol~0.01–0.05%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Cyanocobalamin~0.05–0.1%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Pentylene glycol~0.05–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Sodium dna~0.05–0.2%

Formula

Irritation risk: Low

More about Sodium dna

Tocopherol~0.05–0.2%

Formula

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Caprylyl/capryl glucoside~0.1–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Caprylyl/capryl glucoside

Ceramide np~0.05–0.25%

Under-dosed

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Oligopeptide-1~0.01–0.1%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Oligopeptide-1

Cetearyl alcohol~0.05–0.2%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Xanthan gum~0.01–0.05%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Gardenia extract

Not recognized

Ingredient list view

Water, Butylene glycol, Glycerin, Isopentyldiol, 1,2-hexanediol, Cetyl ethylhexanoate, Niacinamide, Rosa damascena flower water, Chondrus crispus extract, Saccharum officinarum extract, Rose flower oil, Sodium hyaluronate, Rose extract, Caprylic/capric triglyceride, Propanediol, Squalane, Betaine, Panthenol, Polyacrylate crosspolymer-6, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Sodium stearoyl glutamate, Sodium polyacrylate, Hydrogenated lecithin, Cetearyl glucoside, Ethylhexylglycerin, Adenosine, Citric acid, Sorbitan isostearate, Sodium phytate, Dextrin, Beta-glucan, Dipropylene glycol, Cyanocobalamin, Pentylene glycol, Sodium dna, Tocopherol, Caprylyl/capryl glucoside, Ceramide np, Oligopeptide-1, Cetearyl alcohol, Xanthan gum, Unknown

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🇦🇺 Lila Beauty (AU)40 ml

≈ $17.22

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🇦🇺 Amazon Australia (AU)Price as of 11/4 21:03 GMT

≈ $23.19

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🇬🇧 Amazon UK (UK)Price as of 11/6 18:00 GMT

≈ $24.83

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MEDIHEALPDRN Lifting SerumYOUR PRODUCT	MedicubeGlutathione Glow Serum	Make P:remInteca Soothing Ampoule	ArenciaDeep Water Surge Serum
Match	—	89%	89%	87%
Price	—	$15.83	$20.27	$32.63
Shared key ingredients	—	10 of 14	10 of 14	8 of 14
Key difference	—	Caprylic/Capric Triglyceride	Madecassic Acid	Copper Tripeptide-1
Irritancy	Medium	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"MEDIHEAL - Buy Mediheal PDRN Lifting Serum in Australia - Korean Skincare Online" is effective for: Anti-aging, Moisturizing, Anti-blemish and Evens skin tone

Ingredient callouts

Ceramides (ceramide np 0.05% - 0.25%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
Peptides (oligopeptide-1 0.01% - 0.10%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.01% - 0.05%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Humectants (sodium hyaluronate 0.15% - 0.60% and glycerin 2.90% - 4.30%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.