Medicube

Medicube PDRN Pink Caffeine Night Wrapping Mask

Name: Medicube - PDRN Pink Caffeine Night Wrapping Mask
Brand: Medicube

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Anti-aging

Niacinamide, Adenosine + 13 more

Works well

What the product description says

“Firms and lifts with PDRN and Collagen for sculpted skin.”

Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, aspartic acid, copper tripeptide-1, hexapeptide-9, lysine, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, serine, threonine, tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.3–2.8%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.5–0.75%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.25–0.45%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.4%

LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.35%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Hexapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Nonapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.25–0.45%

Moisturizing

Niacinamide, Tripeptide-1 + 36 more

Works well

What the product description says

“The formula creates a protective film that locks in moisture while supporting your skin's natural elasticity for a noticeably firmer appearance.”

Source: senti senti

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, allantoin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, chondrus crispus extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, hexapeptide-9, niacinamide, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, tripeptide-1

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.3–2.8%

Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.35%

Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Nonapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Hexapeptide-9Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.6–5.6%

AllantoinKey active· HumectantEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.7–1.05%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.5–0.75%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.45–0.65%

TyrosineKey activeEffect: High~0.25–0.4%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.4%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.25–0.45%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.25–0.45%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.25–0.45%

LysineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.25–0.45%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.25–0.4%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.25–0.45%

Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.25–0.5%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.25–0.45%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.25–0.45%

HistidineKey active· HumectantEffect: High~0.25–0.4%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.25–0.45%

ProlineKey activeEffect: Medium~0.25–0.45%

MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.2–0.4%

CysteineKey activeEffect: HighMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.2–0.4%

CollagenKey activeEffect: MediumCannot penetrate the skin barrier so is not particularly useful in skincare products~0.15–0.25%

AlginEffect: LowUsed to thicken product formulation. Can help attract water to the upper layer of the skin~1.4–1.7%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.3–0.55%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%

Rosa damascena flower oilEffect: LowUsed as a fragrance. Can be irritating~0.25–0.5%

Evens skin tone

Side benefit · Niacinamide, Alanine + 2 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine, cysteine.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.25–0.45%

CysteineEffect: LowMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.2–0.4%

Anti-blemish

Side benefit · Niacinamide, Allantoin

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

AllantoinEffect: LowHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.7–1.05%

Anti-oxidation

Side benefit · Cysteine, Adenosine + 3 more

May help

This product contains antioxidants (cysteine) that can help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is some human evidence for this effect in skin, though it is smaller or less consistent than the evidence for the best antioxidants.

CysteineKey activeEffect: MediumMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.2–0.4%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.5–0.75%

CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.25–0.5%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.45%

Can it cause trouble?

Irritancy

1 strong irritant: Rosa damascena flower oil

Medium risk

We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Rosa damascena flower oilUsed as a fragrance. Can be irritatingHigh~0.25–0.5%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.25–0.45%est.

Polyvinyl alcoholHelps improve the product textureMedium~3.1–3.8%est.

Benzyl glycolHelps dissolve other ingredients and preserve productsMedium~1.9–2.3%est.

EthylhexylglycerinA preservativeMedium~0.55–0.85%est.

1,2-hexanediolA preservativeMedium~0.4–0.6%est.

Disodium edtaStabilizes the product formulationMedium~0.4–0.65%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.5%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.45%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.25–0.45%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

AlginUsed to thicken product formulation. Can help attract water to the upper layer of the skin3/5~1.4–1.7%est.

Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.25–0.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.6–5.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Glycereth-26~3.9–4.8%

Formula

Irritation risk: Low

Helps create a thicker product consistency

More about Glycereth-26

Polyvinyl alcohol~3.1–3.8%

Irritant · medium

Irritation risk: Medium

Helps improve the product texture

More about Polyvinyl alcohol

Niacinamide~2.3–2.8%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Benzyl glycol~1.9–2.3%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients and preserve products

More about Benzyl glycol

Xanthan gum~1.6–1.9%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Algin~1.4–1.7%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Used to thicken product formulation. Can help attract water to the upper layer of the skin

More about Algin

C12-14 alketh-12~1.2–1.5%

Formula

Irritation risk: Low

More about C12-14 alketh-12

Allantoin~0.7–1.05%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Synthetic fluorphlogopite~0.7–1.1%

Formula

Irritation risk: Low

A mineral that is used as an optical filter (makes the skin looks nicer through light reflection) and to improve the texture of cosmetic products

More about Synthetic fluorphlogopite

Ethylhexylglycerin~0.55–0.85%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Adenosine~0.5–0.75%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Cyanocobalamin~0.45–0.65%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

1,2-hexanediol~0.4–0.6%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Disodium edta~0.4–0.65%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Titanium dioxide~0.5–0.8%

Formula

Irritation risk: Low

Works for

Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide

Sodium dna~0.3–0.6%

Formula

Irritation risk: Low

More about Sodium dna

Butylene glycol~0.3–0.55%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Rosa damascena flower oil~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Moisturizing

Used as a fragrance. Can be irritating

More about Rosa damascena flower oil

Caffeine~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Propanediol~0.3–0.5%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Ascorbic acid~0.25–0.45%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Tocopheryl acetate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Chondrus crispus extract~0.25–0.5%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract

Glycine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Dimethylsilanol hyaluronate~0.25–0.45%

Formula

Irritation risk: Low

More about Dimethylsilanol hyaluronate

Hydrolyzed sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Hydrolyzed hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Serine~0.25–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

Glutamic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Potassium hyaluronate~0.25–0.45%

Formula

Irritation risk: Low

More about Potassium hyaluronate

Hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Sodium hyaluronate crosspolymer~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Hydroxypropyltrimonium hyaluronate~0.25–0.5%

Formula

Irritation risk: Low

More about Hydroxypropyltrimonium hyaluronate

Aspartic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Leucine~0.25–0.45%

Formula

Irritation risk: Low

More about Leucine

Sodium hyaluronate dimethylsilanol~0.25–0.4%

Formula

Irritation risk: Low

More about Sodium hyaluronate dimethylsilanol

Collagen extract~0.25–0.45%

Formula

Irritation risk: Low

More about Collagen extract

Hydrolyzed elastin~0.25–0.5%

Formula

Irritation risk: Low

More about Hydrolyzed elastin

Alanine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Lysine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine

Sodium acetylated hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Arginine~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Tyrosine~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Phenylalanine~0.25–0.45%

Formula

Irritation risk: Low

More about Phenylalanine

Valine~0.25–0.4%

Formula

Irritation risk: Low

More about Valine

Threonine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Proline~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Isoleucine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Caprylyl glycol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Histidine~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Histidine

Methionine~0.2–0.4%

Formula

Irritation risk: Low

More about Methionine

Cysteine~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Might help neutralize free radicals in skin and might be helpful against hyperpigmentation

More about Cysteine

Mannitol~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol

Acetyl hexapeptide-8~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Copper tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1

Palmitoyl tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl pentapeptide-4~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4

Collagen~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

Cannot penetrate the skin barrier so is not particularly useful in skincare products

More about Collagen

Hexapeptide-9~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-9

Nonapeptide-1~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nonapeptide-1

Ingredient list view

Water, Glycerin, Glycereth-26, Polyvinyl alcohol, Niacinamide, Benzyl glycol, Xanthan gum, Algin, C12-14 alketh-12, Allantoin, Synthetic fluorphlogopite, Ethylhexylglycerin, Adenosine, Cyanocobalamin, 1,2-hexanediol, Disodium edta, Titanium dioxide, Sodium dna, Butylene glycol, Rosa damascena flower oil, Caffeine, Propanediol, Ascorbic acid, Tocopheryl acetate, Chondrus crispus extract, Glycine, Dimethylsilanol hyaluronate, Hydrolyzed sodium hyaluronate, Hydrolyzed hyaluronic acid, Serine, Glutamic acid, Sodium hyaluronate, Potassium hyaluronate, Hyaluronic acid, Sodium hyaluronate crosspolymer, Hydroxypropyltrimonium hyaluronate, Aspartic acid, Leucine, Sodium hyaluronate dimethylsilanol, Collagen extract, Hydrolyzed elastin, Alanine, Lysine, Sodium acetylated hyaluronate, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Caprylyl glycol, Histidine, Methionine, Cysteine, Mannitol, Acetyl hexapeptide-8, Copper tripeptide-1, Tripeptide-1, Palmitoyl tripeptide-1, Palmitoyl pentapeptide-4, Collagen, Hexapeptide-9, Nonapeptide-1

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$35.01

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MedicubePDRN Pink Caffeine Night Wrapping MaskYOUR PRODUCT	Bliv:UCollagen Bouncing Firming Gel Mask	GlowiestDream Glow Slow-Aging Mask - 30 Masks	numbuzinNo.9 NAD Bio Lifting-sil Full Face Mask bottom sheet
Match	—	81%	79%	78%
Price	$35.01	$2.68−$32.33	$24.99−$10.02	$20.27−$14.74
Shared key ingredients	—	29 of 34	16 of 34	12 of 34
Key difference	—	Acetyl Tetrapeptide-2	Phytosphingosine	Myristoyl Pentapeptide-17
Irritancy	Medium	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

More alternatives: Eqqualberry Collagen Pore Tight Up Hydrogel Mask Avatara Niacinamide Water Gel Face Mask

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Product summary

"Medicube - PDRN Pink Caffeine Night Wrapping Mask" is effective for: Anti-aging, Evens skin tone, Moisturizing and Anti-blemish

Ingredient callouts

A good concentration of Niacinamide (2.30% - 2.80%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.25% - 0.45%) it cannot have a noticeable benefit for the skin.
Peptides (nonapeptide-1 0.10% - 0.15%, hexapeptide-9 0.10% - 0.15%, palmitoyl pentapeptide-4 0.15% - 0.30%, palmitoyl tripeptide-1 0.20% - 0.35%, tripeptide-1 0.20% - 0.35%, copper tripeptide-1 0.20% - 0.35% and acetyl hexapeptide-8 0.20% - 0.35%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.50% - 0.75%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
In addition, this product contains Allantoin (0.70% - 1.05%). Allantoin is helpful in wound-healing and can help restore the skin barrier faster. It might also be able to improve scars, but the evidence is not very strong for this.
Humectants (hexapeptide-9 0.10% - 0.15%, acetyl hexapeptide-8 0.20% - 0.35%, mannitol 0.20% - 0.40%, histidine 0.25% - 0.40%, arginine 0.25% - 0.40%, sodium acetylated hyaluronate 0.25% - 0.45%, alanine 0.25% - 0.45%, aspartic acid 0.25% - 0.45%, sodium hyaluronate crosspolymer 0.25% - 0.45%, hyaluronic acid 0.25% - 0.45%, sodium hyaluronate 0.25% - 0.45%, glutamic acid 0.25% - 0.45%, hydrolyzed hyaluronic acid 0.25% - 0.45%, glycine 0.25% - 0.45% and glycerin 4.60% - 5.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 29 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Safety Assessment of Glycerin Ethoxylates as Used in Cosmeticscir-safety.org
3
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
4
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
5
Profile of wound healing process induced by allantoinscielo.br
6
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
7
Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trialpubmed.ncbi.nlm.nih.gov
8
Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasisncbi.nlm.nih.gov
9
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
10
Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts ec.europa.eu
11
Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiencyjamanetwork.com
12
Functional glycine receptor in cultured human keratinocytesonlinelibrary.wiley.com
13
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
14
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
15
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
16
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
17
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
18
Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proofncbi.nlm.nih.gov
19
In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmnessncbi.nlm.nih.gov
20
Combination of amino acids reduces pigmentation in B16F0 melanoma cellsncbi.nlm.nih.gov
21
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
22
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trialonlinelibrary.wiley.com
23
Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseasespatents.google.com
24
Safety Assessment of α-Amino Acids as Used in Cosmeticsciteseerx.ist.psu.edu
25
The Potential Uses of N-acetylcysteine in Dermatology: A Reviewncbi.nlm.nih.gov
26
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
27
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
28
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
29
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com

MedicubePDRN Pink Caffeine Night Wrapping Mask

Buy on Amazon$35.01 · as of 11/14 12:49 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$35.01 · as of 11/14 12:49 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.