Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Evens skin tone
- Anti-blemish
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
Based on the ingredient list, "Medicube - AGE-R PDRN Booster Gel" can work well for skin moisturization. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Medicube - AGE-R PDRN Booster Gel ticks this box. Humectants in this product (alanine, glycerin, glycine, hyaluronic acid and hydrolyzed collagen) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide np, hydrolyzed collagen, caprylic/capric triglyceride and moringa oleifera seed oil in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- We particularly like that there is a good concentration of Niacinamide (2.40% - 2.90%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
- Another benefit is that this moisturizer contain ceramides (ceramide np 0.35% - 0.65%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- Adenosine 0.45% - 0.65%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Irritation risk
This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 21.57$ in the United States.
For a detailed price comparison: click here.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: atelocollagen, lysine, serine, threonine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
Moisturizing
What does the product description say?
Hydrating gel cares for the skin and makes the outer skin glow.
Source: Yesstyle
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
alanine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, hydrolyzed collagen.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
A protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Help attract water to the upper layer of the skin, soften it and support the skin barrier function
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
Attracts water into the upper layer of the skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps to attract water to the upper layer of the skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
Cannot penetrate the skin barrier so is not particularly useful in skincare products
Helps attract water to the upper layer of the skin and soften it
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Medicube AGE-R PDRN Booster Gel | Current | $21.57 | |
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BIOHEAL BOH Ceramide Water Gel Cream | 85% | $22.29 | |
Evercell Radiance Lifting Cream | 83% | $12.35 | |
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Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
A protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps to attract water to the upper layer of the skin
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
Help attract water to the upper layer of the skin, soften it and support the skin barrier function
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
A plant extract that might help neutralize free radicals in skin. It can be irritating
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid
Attracts water into the upper layer of the skin
Comedogenic ingredients
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and soften it
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
An aromatic blend of unspecified and possibly irritating ingredients
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A plant extract that might help neutralize free radicals in skin. It can be irritating
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin
A protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid
Cannot penetrate the skin barrier so is not particularly useful in skincare products
Help attract water to the upper layer of the skin, soften it and support the skin barrier function
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Ingredient list view
Water, Methylpropanediol, Glycereth-26, Glycerin, Niacinamide, 1,2-hexanediol, Polyglycerin-3, Methyl gluceth-20, Methyl gluceth-10, Caprylic/capric triglyceride, Acrylates/c10-30 alkyl acrylate crosspolymer, Tromethamine, Allantoin, C12-14 alketh-12, Soluble elastin, Ethylhexylglycerin, Parfum, Adenosine, Sodium hyaluronate, Eclipta prostrata extract, Butylene glycol, Melia azadirachta leaf extract, Soluble collagen, Moringa oleifera seed oil, Phosphatidylcholine, Hyaluronic acid, Sodium hyaluronate crosspolymer, Hydrolyzed sodium hyaluronate, Hydrolyzed hyaluronic acid, Sodium dna, Atelocollagen, Desamido collagen, Ceramide np, Prunella vulgaris extract, Fucus vesiculosus extract, Hydrolyzed collagen, Sodium acetylated hyaluronate, Hydroxypropyltrimonium hyaluronate, Collagen, Collagen amino acids, Glycine, Serine, Procollagen, Lysine, Alanine, Threonine, Proline, Arginine
- Safety Assessment of Glycerin Ethoxylates as Used in Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Safety Assessment of Tromethamine as Used in Cosmetics
- Profile of wound healing process induced by allantoin
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Potent Antioxidative and UVB Protective Effect of Water Extract of Eclipta prostrata L.
- Melia azedarach
- Preliminary and Pharmacological Profile of Melia azedarach L.: An Overview
- Moringa oleifera seed oil: Composition, nutritional aspects and health attributes
- Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Health
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- The Efficacy and Safety of Succinylated Atelocollagen and Adenosine for the Treatment of Periorbital Wrinkles
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies
- Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency
- Functional glycine receptor in cultured human keratinocytes
- Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
- Combination of amino acids reduces pigmentation in B16F0 melanoma cells