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MEDI-PEEL Bio-Intense Gluthione 600 White Ampoule
MEDI-PEEL

MEDI-PEEL Bio-Intense Gluthione 600 White Ampoule

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Evens skin tone
Niacinamide, Glutathione + 2 more
Works well
What the product description says
“An intensive whitening ampoule that improves blemishes and dull skin tone, leaving skin moisturized and clear.”
Source: Yesstyle

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.8–5.6%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~2.6–3.9%
Phyllanthus emblica fruit extractEffect: Low, below effective doseA plant extract that might be helpful in neutralizing free radicals and have a skin lightening effect if used in high enough concentrations~0.35–0.85%
Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.1–0.35%
Anti-blemish
Side benefit the brand mentions · Niacinamide, Sodium ascorbyl phosphate + 1 more
Works well
What the product description says
“An intensive whitening ampoule that improves blemishes and dull skin tone, leaving skin moisturized and clear.”
Source: Yesstyle

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.8–5.6%
Sodium ascorbyl phosphateUnder-dosedA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.1–0.45%
Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.1–0.35%

Can it cause trouble?

Irritancy
6 strong irritants: Zanthoxylum piperitum fruit extract, Parfum + 4 more — patch-test recommended
High risk
We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Zanthoxylum piperitum fruit extractPlant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smellHigh~1.6–2.5%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.55–1.35%est.
Primula veris extract—High~0.1–0.45%est.
Mentha piperita leaf extractUsed as a fragrance and can be irritatingHigh~0.1–0.45%est.
Melissa officinalis leaf extractA plant extract that is added for its fragrance. Can be irritatingHigh~0.1–0.45%est.
Malva sylvestris extract—High~0.1–0.5%est.
Achillea millefolium extractPlant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritatingHigh~0.15–0.55%est.
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.1–0.35%est.
PyridoxineMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritatingHigh~0.1–0.4%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~2.6–3.9%est.
1,2-hexanediolA preservativeMedium~1.1–1.6%est.
Phyllanthus emblica fruit extractA plant extract that might be helpful in neutralizing free radicals and have a skin lightening effect if used in high enough concentrationsMedium~0.35–0.85%est.
EthylhexylglycerinA preservativeMedium~0.15–0.65%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.15–0.65%est.
Laureth-7Helps oil and water mix togetherMedium~0.15–0.7%est.
Polyglyceryl-10 stearateHelps water and oil mix together and softens the upper layer of the skinMedium~0.15–0.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.55%est.
Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.1–0.45%est.
Thiamine hclCan help attract water to the upper layer of the skin. Is studied as a mosquito repellentMedium~0.1–0.4%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
Alternatives
Cheaper, or higher on efficacy
EGF Hyper-Active Bubble Ampoule
fromrier EGF Hyper-Active Bubble Ampoule
Cheaper82% match
$21.00
SEOUL 1988 Serum : Retinal Liposome 2% + Black Ginseng
K-SECRET SEOUL 1988 Serum : Retinal Liposome 2% + Black Ginseng
Cheaper79% match
$11.84
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Niacinamide~3.8–5.6%
Hero · Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Helianthus annuus seed oil~3.6–5.4%
Formula
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Glutathione~2.6–3.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
1,2-hexanediol~1.1–1.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Zanthoxylum piperitum fruit extract~1.6–2.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smell

More about Zanthoxylum piperitum fruit extract
Pulsatilla koreana extract~1.4–2.1%
Formula
Irritation risk
Low
More about Pulsatilla koreana extract
Usnea barbata extract~1.2–1.9%
Formula
Irritation risk
Low
More about Usnea barbata extract
Cetearyl olivate~1–1.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Parfum~0.55–1.35%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sodium hyaluronate~0.45–1.05%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Phyllanthus emblica fruit extract~0.35–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin toneAnti-aging

A plant extract that might be helpful in neutralizing free radicals and have a skin lightening effect if used in high enough concentrations

More about Phyllanthus emblica fruit extract
C13-14 isoparaffin~0.3–0.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Glycerin~0.2–0.75%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Ethylhexylglycerin~0.15–0.65%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Triethanolamine~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Carbomer~0.15–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Laureth-7~0.15–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Hydrogenated lecithin~0.15–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Polyglyceryl-10 stearate~0.15–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps water and oil mix together and softens the upper layer of the skin

More about Polyglyceryl-10 stearate
Panthenol~0.15–0.55%
Formula
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Tocopheryl acetate~0.15–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Sodium ascorbyl phosphate~0.1–0.45%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate
Veronica officinalis extract~0.1–0.45%
Formula
Irritation risk
Low
More about Veronica officinalis extract
Primula veris extract~0.1–0.45%
Irritant · high
Irritation risk
High
More about Primula veris extract
Mentha piperita leaf extract~0.1–0.45%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha piperita leaf extract
Melissa officinalis leaf extract~0.1–0.45%
Irritant · high
Irritation risk
High

A plant extract that is added for its fragrance. Can be irritating

More about Melissa officinalis leaf extract
Malva sylvestris extract~0.1–0.5%
Irritant · high
Irritation risk
High
More about Malva sylvestris extract
Achillea millefolium extract~0.15–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritating

More about Achillea millefolium extract
Glyceryl linolenate/glyceryl arachidonate
Not recognized
Thiamine hcl~0.1–0.4%
Irritant · medium
Irritation risk
Medium

Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent

More about Thiamine hcl
Retinyl palmitate~0.1–0.35%
Under-dosedIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Pyridoxine~0.1–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Might help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating

More about Pyridoxine
Folic acid~0.1–0.45%
Formula
Irritation risk
Low
Works for
Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid
Biotin~0.1–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin
Cyanocobalamin~0.1–0.35%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Sh-polypeptide-3~0.1–0.35%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-3
Sh-polypeptide-16~0.1–0.3%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-16
Sh-oligopeptide-2~0.05–0.25%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-2
Sh-oligopeptide-1~0.05–0.2%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1
Sh-polypeptide-1~0.05–0.15%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-1
Ingredient list view

Water, Niacinamide, Helianthus annuus seed oil, Glutathione, 1,2-hexanediol, Zanthoxylum piperitum fruit extract, Pulsatilla koreana extract, Usnea barbata extract, Cetearyl olivate, Parfum, Sodium hyaluronate, Phyllanthus emblica fruit extract, C13-14 isoparaffin, Glycerin, Ethylhexylglycerin, Triethanolamine, Carbomer, Laureth-7, Hydrogenated lecithin, Polyglyceryl-10 stearate, Panthenol, Tocopheryl acetate, Sodium ascorbyl phosphate, Veronica officinalis extract, Primula veris extract, Mentha piperita leaf extract, Melissa officinalis leaf extract, Malva sylvestris extract, Achillea millefolium extract, Unknown, Thiamine hcl, Retinyl palmitate, Pyridoxine, Folic acid, Biotin, Cyanocobalamin, Sh-polypeptide-3, Sh-polypeptide-16, Sh-oligopeptide-2, Sh-oligopeptide-1, Sh-polypeptide-1

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Yesstyle30 ml
$26.50 Out of stock
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MEDI-PEELBio-Intense Gluthione 600 White AmpouleYOUR PRODUCTfromrierEGF Hyper-Active Bubble AmpouleNatura BisséInhibit High Definition SerumSUNGBOON EDITORSilk Peptide EGF Intensive Ampoule
Match—82%82%81%
Price—$21.00$457.61$23.40
Shared key ingredients—8 of 168 of 167 of 16
Key difference—Sh-Polypeptide-9Sh-Polypeptide-9Copper Tripeptide-1
Irritancy High Medium High Medium
Drying alcohol————
View product Shop Shop Shop
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More alternatives: Meditime Batoxin Derma Lift-Up SerumK-SECRET SEOUL 1988 Serum : Retinal Liposome 2% + Black Ginseng

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 32 studies and safety reviews.

  1. 1
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  2. 2
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  3. 3
    Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
  4. 4
    Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
  5. 5
    Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
  6. 6
    Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
MEDI-PEEL Bio-Intense Gluthione 600 White Ampoule
MEDI-PEELBio-Intense Gluthione 600 White Ampoule
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