Manyo Glutathione 7 Dark Spot Serum

Manyo Glutathione 7 Dark Spot Serum

Efficacy100/100IrritancyMedium

Works for

Moisturizing
Niacinamide, Acetyl glucosamine + 20 more
Works well
What the product description says
“- 85% more hydration for 24 hours after a single application”
Source: Sephora

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, niacinamide, panthenol

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.45–0.65%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.4–0.65%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.5–3.1%
Tranexamic acidKey activeEffect: HighAn amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally~2–2.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.2%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.95–1.15%
Borago officinalis seed oilKey active· EmollientEffect: HighA plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration~0.7–1.05%
Glycine soja seed extractKey active· EmollientEffect: MediumAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.6–0.9%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.25–0.5%
Polyglutamic acidKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin.~0.2–0.4%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.2–0.35%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.2–0.35%
Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.2–0.4%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.35%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.2–0.35%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.15–0.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.1–3.8%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.45%
Evens skin tone
Niacinamide, Tranexamic acid + 7 more
Works well
What the product description says
“Powered by glutathione, niacinamide, and NAG, this serum targets visible and underlying dark spots for clearer and more even-toned skin in as fast as seven days.”
Source: Sephora

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine, alpha-arbutin, glutathione, kojic acid, niacinamide, tranexamic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: arbutin, glycine soja seed extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
Tranexamic acidKey activeEffect: HighAn amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally~2–2.4%
ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~1.5–1.8%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.95–1.15%
Alpha-arbutinKey activeEffect: HighMight help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin~0.5–0.75%
Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.45–0.65%
Kojic acidKey activeEffect: HighHelps to reduce hyperpigmentation and neutralize free radicals. Can be irritating~0.2–0.4%
Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.6–0.9%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.4%
Anti-oxidation
Side benefit · Arbutin, Glutathione + 10 more
Works well

This product contains antioxidants (glutathione, kojic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - arbutin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

ArbutinKey activeEffect: MediumBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin~1.5–1.8%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.95–1.15%
Kojic acidKey activeEffect: HighHelps to reduce hyperpigmentation and neutralize free radicals. Can be irritating~0.2–0.4%
Borago officinalis seed oilEffect: LowA plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration~0.7–1.05%
Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.6–0.9%
Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.25–0.45%
Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.25–0.5%
Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.2–0.4%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.25%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.45%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.4%
Anti-aging
Side benefit · Niacinamide, Acetyl glucosamine + 5 more
Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine, niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.45–0.65%
Glycine soja seed extractEffect: LowAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.~0.6–0.9%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.35%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.45%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.4%
Anti-blemish
Side benefit · Niacinamide, Melia azadirachta leaf extract + 2 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.2–0.4%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%
Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.45%

Can it cause trouble?

Irritancy
2 strong irritants: Ocimum sanctum leaf extract, Citrus limon fruit extract
Medium risk
We flagged 21 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.25–0.45%est.
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.2–0.4%est.
Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.2–0.35%est.
Kojic acidHelps to reduce hyperpigmentation and neutralize free radicals. Can be irritatingHigh~0.2–0.4%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.2–0.4%est.
Citrus limon fruit extractUsed as a fragrance. Can be irritating and cause photosensitivityHigh~0.2–0.4%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.5–3.1%est.
ArbutinBeta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutinMedium~1.5–1.8%est.
1,2-hexanediolA preservativeMedium~0.75–1.1%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.95–1.15%est.
Glycine soja seed extractAn emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.Medium~0.6–0.9%est.
Alpha-arbutinMight help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutinMedium~0.5–0.75%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.45–0.65%est.
EthylhexylglycerinA preservativeMedium~0.3–0.55%est.
Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.25–0.5%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.25–0.45%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.15–0.3%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.2–0.35%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.2–0.35%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.25%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.2–0.4%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
C13-15 alkane~6.5–8%
Formula
Irritation risk
Low

Helps dissolve other ingredients in the formula

More about C13-15 alkane
Niacinamide~4.2–5.1%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneAnti-blemishMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Butylene glycol~3.1–3.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Caprylic/capric triglyceride~2.5–3.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Tranexamic acid~2–2.4%
Key active
Irritation risk
Low
Works for
Evens skin toneMoisturizing

An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally

More about Tranexamic acid
Glycerin~1.8–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Arbutin~1.5–1.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-oxidation

Beta-arbutin. Can help to reduce hyperpigmentation and has an anti-oxidant effect when used in high enough concentration. Is less effective compared to alpha-arbutin

More about Arbutin
1,2-hexanediol~0.75–1.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Glutathione~0.95–1.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
Borago officinalis seed oil~0.7–1.05%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationAnti-oxidation

A plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration

More about Borago officinalis seed oil
Glycine soja seed extract~0.6–0.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-agingReduces rednessEvens skin toneAnti-oxidation

An emollient that helps soften the skin. Might be somewhat helpful in evening the skin tone.

More about Glycine soja seed extract
Alpha-arbutin~0.5–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin

More about Alpha-arbutin
Acetyl glucosamine~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingEvens skin toneAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Panthenol~0.4–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Xanthan gum~0.45–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Potassium cetyl phosphate~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Allantoin~0.3–0.55%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Ethylhexylglycerin~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Melia azadirachta flower extract~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ocimum sanctum leaf extract~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Polyglutamic acid~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin.

More about Polyglutamic acid
Melia azadirachta leaf extract~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Curcuma longa root extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract
Corallina officinalis extract~0.2–0.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract
Squalane~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Sodium hyaluronate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Kojic acid~0.2–0.4%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-oxidation

Helps to reduce hyperpigmentation and neutralize free radicals. Can be irritating

More about Kojic acid
Ascorbic acid~0.2–0.4%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Centella asiatica extract~0.25–0.45%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Tocopherol~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Citrus limon fruit extract~0.2–0.4%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating and cause photosensitivity

More about Citrus limon fruit extract
Hydroxypropyltrimonium hyaluronate~0.2–0.4%
Formula
Hydrolyzed hyaluronic acid~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Sodium acetylated hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Hyaluronic acid~0.2–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Hydrolyzed sodium hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Sodium hyaluronate crosspolymer~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
Polyglyceryl-10 laurate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Potassium hyaluronate~0.2–0.35%
Formula
Phosphatidylcholine~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Tocopheryl acetate~0.15–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ingredient list view

Water, C13-15 alkane, Niacinamide, Butylene glycol, Caprylic/capric triglyceride, Tranexamic acid, Glycerin, Arbutin, 1,2-hexanediol, Glutathione, Borago officinalis seed oil, Glycine soja seed extract, Alpha-arbutin, Acetyl glucosamine, Panthenol, Xanthan gum, Potassium cetyl phosphate, Allantoin, Ethylhexylglycerin, Melia azadirachta flower extract, Disodium edta, Ocimum sanctum leaf extract, Polyglutamic acid, Melia azadirachta leaf extract, Curcuma longa root extract, Corallina officinalis extract, Squalane, Sodium hyaluronate, Kojic acid, Ascorbic acid, Centella asiatica extract, Tocopherol, Citrus limon fruit extract, Hydroxypropyltrimonium hyaluronate, Hydrolyzed hyaluronic acid, Sodium acetylated hyaluronate, Hyaluronic acid, Hydrolyzed sodium hyaluronate, Sodium hyaluronate crosspolymer, Polyglyceryl-10 laurate, Potassium hyaluronate, Phosphatidylcholine, Tocopheryl acetate

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Amazon USPrice as of 11/13 15:01 GMT
$19.90
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Sephora
$21.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ManyoGlutathione 7 Dark Spot SerumYOUR PRODUCTAwake BeautyGlow Pill Super SerumFace Reality SkincareglowTone Corrective SerumnumbuzinNO.1 PANTOTHENIC B5 ACTIVE SOOTHING SERUM
Match—83%82%82%
Price$21.00—$64.00+$43.00$16.27−$4.73
Shared key ingredients—9 of 249 of 2413 of 24
Key difference—Hydrolyzed GlycosaminoglycansAzelaic AcidBetaine
Irritancy Medium Low Medium Medium
Drying alcohol—— Contains drying alcohol —
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More alternatives: Paula's choice 10% Niacinamide BoosterCOSRX The Alpha-Arbutin 2 Discoloration Care Serum

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 45 studies and safety reviews.

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Manyo Glutathione 7 Dark Spot Serum
ManyoGlutathione 7 Dark Spot Serum

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.