Manyo

Manyo Bifida Infusion Shot Ampoule 1DX

Name: Manyo - Bifida Infusion Shot Ampoule 1DX
Brand: Manyo

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Moisturizing

Niacinamide, Ceramide np + 18 more

Works well

What the product description says

“Enriched with Hyaluronic Acid, Ceramide NP, Allantoin, and Panthenol , it hydrates, refines texture, and soothes without stickiness. Dermatologically tested.”

Source: Manyo

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: fructooligosaccharides, fructose.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: ceramide np, hydrogenated polyisobutene.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.6–3.9%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.55%

Bifida ferment lysateKey activeEffect: HighConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect68%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.5–2.3%

Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~1–1.6%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.4–0.9%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.2–0.7%

FructooligosaccharidesKey active· HumectantEffect: HighHelp attract water to the upper layer of the skin~0.15–0.65%

FructoseKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.15–0.6%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4.1–6.1%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.3–2%

Glyceryl polymethacrylate· Humectant, EmollientEffect: LowUsed to create a nice product texture~0.35–0.85%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.2–0.75%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.15–0.6%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.4%

GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.5%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.15–0.7%

PanthenolUnder-dosedHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.15–0.5%

AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.45%

Anti-aging

Not advertised by the brand · Niacinamide, Adenosine + 2 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.6–3.9%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%

Evens skin tone

Not advertised by the brand · Niacinamide, Bifida ferment lysate + 1 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: bifida ferment lysate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Bifida ferment lysateEffect: LowConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect68%

Anti-blemish

Not advertised by the brand · Niacinamide, Allantoin + 1 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.45%

Anti-oxidation

Not advertised by the brand · Bifida ferment lysate, Chlorella vulgaris extract + 3 more

May help

This product contains antioxidants (bifida ferment lysate) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Bifida ferment lysateKey activeEffect: MediumConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect68%

Chlorella vulgaris extractEffect: LowA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~1–1.6%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.4%

Can it cause trouble?

Irritancy

10 flagged ingredients

Medium risk

We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

MethylpropanediolHelps dissolve other ingredients in a formulationMedium~23–35%est.

1,2-hexanediolA preservativeMedium~2.2–3.3%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.3–2%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~1–1.6%est.

Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.2–0.8%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.35–0.8%est.

EthylhexylglycerinA preservativeMedium~0.15–0.5%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.15–0.5%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.15–0.7%est.

Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.1–0.5%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~1–1.6%est.

Theobroma cacao extract—3/5~0.5–1.15%est.

Alternatives

Cheaper, or higher on efficacy

Beauty of Joseon Calming Barrier Serum

Cheaper84% match

$13.60

Elishacoy Kombucha Gyeol-Biome Ampoule

Cheaper83% match

$19.60

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Ingredients

Filter by role to see what each ingredient is doing.

Bifida ferment lysate68%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect

More about Bifida ferment lysate

Methylpropanediol~23–35%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol

Dipropylene glycol~5.4–8.1%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Butylene glycol~4.1–6.1%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

1,2-hexanediol~2.2–3.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Niacinamide~2.6–3.9%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Water~1.9–2.8%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~1.5–2.3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Pentylene glycol~1.3–2%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Chlorella vulgaris extract~1–1.6%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

MoisturizingAnti-inflammatoryAnti-oxidation

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract

Hydrolyzed sponge~0.8–1.25%

Formula

Irritation risk: Low

More about Hydrolyzed sponge

Theobroma cacao extract~0.5–1.15%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Theobroma cacao extract

Sodium hyaluronate~0.4–0.9%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Glyceryl polymethacrylate~0.35–0.85%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture

More about Glyceryl polymethacrylate

Polyglyceryl-10 laurate~0.2–0.8%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate

Ammonium acryloyldimethyltaurate/vp copolymer~0.2–0.75%

Formula

Irritation risk: Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer

Glucose~0.2–0.7%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Acrylates/c10-30 alkyl acrylate crosspolymer~0.35–0.8%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Diethoxyethyl succinate~0.2–0.75%

Formula

Irritation risk: Low

Helps dissolve other ingredients in the formulation

More about Diethoxyethyl succinate

Hydrogenated lecithin~0.2–0.75%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Fructooligosaccharides~0.15–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Help attract water to the upper layer of the skin

More about Fructooligosaccharides

Fructose~0.15–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Fructose

Hydrogenated polyisobutene~0.2–0.75%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Panthenol~0.15–0.5%

Under-dosed

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Tromethamine~0.15–0.5%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Ethylhexylglycerin~0.15–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Allantoin~0.1–0.45%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Adenosine~0.15–0.55%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Dextrin~0.15–0.6%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Gluconolactone~0.15–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-agingEvens skin toneExfoliationAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Sodium phytate~0.1–0.45%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Caprylic/capric triglyceride~0.15–0.7%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Tocopherol~0.1–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Ceramide np~0.15–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Hyaluronic acid/polyisopropylacrylamide copolymer~0.1–0.3%

Formula

Irritation risk: Low

More about Hyaluronic acid/polyisopropylacrylamide copolymer

Sodium stearoyl glutamate~0.1–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate

Ingredient list view

Bifida ferment lysate, Methylpropanediol, Dipropylene glycol, Butylene glycol, 1,2-hexanediol, Niacinamide, Water, Glycerin, Pentylene glycol, Chlorella vulgaris extract, Hydrolyzed sponge, Theobroma cacao extract, Sodium hyaluronate, Glyceryl polymethacrylate, Polyglyceryl-10 laurate, Ammonium acryloyldimethyltaurate/vp copolymer, Glucose, Acrylates/c10-30 alkyl acrylate crosspolymer, Diethoxyethyl succinate, Hydrogenated lecithin, Fructooligosaccharides, Fructose, Hydrogenated polyisobutene, Panthenol, Tromethamine, Ethylhexylglycerin, Allantoin, Adenosine, Dextrin, Gluconolactone, Sodium phytate, Caprylic/capric triglyceride, Tocopherol, Ceramide np, Hyaluronic acid/polyisopropylacrylamide copolymer, Sodium stearoyl glutamate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ManyoBifida Infusion Shot Ampoule 1DXYOUR PRODUCT	Beauty of JoseonCalming Barrier Serum	ElishacoyKombucha Gyeol-Biome Ampoule	I'm fromMushroom Collagen Ampoule
Match	—	84%	83%	81%
Price	$39.00	$13.60−$25.40	$19.60−$19.40	$17.83−$21.17
Shared key ingredients	—	7 of 11	7 of 11	8 of 11
Key difference	—	Lactococcus Ferment Lysate	Glycine	Dipotassium Glycyrrhizate
Irritancy	Medium	Low	Low	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Manyo - Bifida Infusion Shot Ampoule 1DX" is effective for: Anti-aging, Moisturizing, Evens skin tone and Anti-blemish

Ingredient callouts

A good concentration of Niacinamide (2.60% - 3.90%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
Ceramides (ceramide np 0.15% - 0.55%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
Adenosine 0.15% - 0.55%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Humectants (fructose 0.15% - 0.60%, fructooligosaccharides 0.15% - 0.65%, sodium hyaluronate 0.40% - 0.90% and glycerin 1.50% - 2.30%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.