Le Mieux TGF-β BOOSTER

Le Mieux TGF-β BOOSTER

Efficacy87/100IrritancyMedium

Works for

Moisturizing
Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 + 24 more
Works well
What the product description says
“Featuring a revolutionary base of galactomyces ferment filtrate and our Hya10+ Complex, it quenches thirsty skin, smooths fine lines, and lifts for visibly firmer, plumper skin.”
Source: Le Mieux Skincare

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, galactomyces ferment filtrate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: ceramide ns, palmitoyl tetrapeptide-7.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl octapeptide-3, ceramide ns, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, saccharomyces polypeptides

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–1.05%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–1%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.9%
Saccharomyces polypeptidesHeroEffect: High~0.4–0.95%
Ceramide nsHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.4–0.9%
Acetyl octapeptide-3Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.8%
Galactomyces ferment filtrateKey active· HumectantEffect: HighA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~23–34%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~6.7–10%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~3.9–5.9%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~1.8–2.7%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~1.3–1.9%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.8–1.25%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.45–1.05%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.7%
AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.3–0.7%
Saccharomyces/copper fermentKey active· HumectantEffect: HighYeast extract that contains copper. Can help to attract water to the upper layer of the skin and can help in skin wound healing~0.3–0.7%
ProlineKey activeEffect: Medium~0.3–0.75%
Saccharomyces/zinc fermentKey active· HumectantEffect: HighYeast extract that contains zinc. Can help to attract water to the upper layer of the skin. Evidence of effectiveness for other benefits is missing~0.2–0.75%
Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.2–0.7%
GlycoproteinsKey activeEffect: High~0.2–0.75%
Saccharomyces/manganese fermentKey activeEffect: MediumA yeast extract that helps attract water to the upper layer of the skin~0.2–0.75%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.2–0.75%
Capryloyl glycineKey activeEffect: MediumHelps oil and water mix together, preserve cosmetic products, and attract water to the upper layer of the skin~0.15–0.65%
Oryza sativa bran waterEffect: LowMight be somewhat helpful for attracting water to the upper layer of the skin~5.3–7.9%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.7%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.15–0.7%
Anti-aging
Galactomyces ferment filtrate, Palmitoyl tripeptide-1 + 8 more
May help
What the product description says
“Featuring a revolutionary base of galactomyces ferment filtrate and our Hya10+ Complex, it quenches thirsty skin, smooths fine lines, and lifts for visibly firmer, plumper skin.”
Source: Le Mieux Skincare

This product contains acetyl octapeptide-3, folic acid, galactomyces ferment filtrate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, saccharomyces polypeptides, serine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Galactomyces ferment filtrateKey activeEffect: MediumA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~23–34%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–1%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–1.05%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.9%
Saccharomyces polypeptidesKey activeEffect: Medium~0.4–0.95%
Acetyl octapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.8%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.7%
Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.2–0.75%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~3.9–5.9%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.15–0.7%
Anti-oxidation
Side benefit · Galactomyces ferment filtrate, Superoxide dismutase + 1 more
Works well

This product contains antioxidants (galactomyces ferment filtrate, superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - ginkgo biloba leaf extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Galactomyces ferment filtrateKey activeEffect: HighA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~23–34%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.45–1.05%
Ginkgo biloba leaf extractKey activeEffect: MediumA plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating~0.2–0.75%
Evens skin tone
Side benefit · Galactomyces ferment filtrate, Alanine + 1 more
May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: alanine, galactomyces ferment filtrate.

Galactomyces ferment filtrateKey activeEffect: MediumA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~23–34%
AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.3–0.7%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.15–0.7%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 6 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Ginkgo biloba leaf extractA plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritatingHigh~0.2–0.75%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.5%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~1.8–2.7%est.
Saccharomyces/manganese fermentA yeast extract that helps attract water to the upper layer of the skinMedium~0.2–0.75%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.7%est.
EthylhexylglycerinA preservativeMedium~0.1–0.4%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Enteromorpha compressa extract—3/5~0.2–0.75%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Galactomyces ferment filtrate~23–34%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationMattifyingEvens skin toneAnti-agingAnti-blemish

A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores

More about Galactomyces ferment filtrate
Sodium hyaluronate~6.7–10%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Oryza sativa bran water~5.3–7.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Might be somewhat helpful for attracting water to the upper layer of the skin

More about Oryza sativa bran water
Hyaluronic acid~3.9–5.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Zinc hydrolyzed hyaluronate~3.2–4.7%
Formula
Hydroxypropyltrimonium hyaluronate~2.6–3.9%
Formula
Sodium hyaluronate dimethylsilanol~2.1–3.1%
Formula
Sodium hyaluronate crosspolymer~1.8–2.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
C12-13 alkyl glyceryl hydrolyzed hyaluronate~1.6–2.4%
Formula
Hydrolyzed hyaluronic acid~1.3–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Sodium acetylated hyaluronate~0.8–1.25%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Ascorbyl propyl hyaluronate~0.55–1.25%
Formula
Superoxide dismutase~0.45–1.05%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-oxidation

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase
Saccharomyces polypeptides~0.4–0.95%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Saccharomyces polypeptides
Oligopeptide-225
Not recognized
Palmitoyl tetrapeptide-7~0.45–1.05%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Palmitoyl tripeptide-5~0.4–0.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Palmitoyl tripeptide-1~0.45–1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Acetyl octapeptide-3~0.35–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl octapeptide-3
Ceramide ns~0.4–0.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ns
Saccharomyces/copper ferment~0.3–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Yeast extract that contains copper. Can help to attract water to the upper layer of the skin and can help in skin wound healing

More about Saccharomyces/copper ferment
Saccharomyces/zinc ferment~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Yeast extract that contains zinc. Can help to attract water to the upper layer of the skin. Evidence of effectiveness for other benefits is missing

More about Saccharomyces/zinc ferment
Saccharomyces/manganese ferment~0.2–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A yeast extract that helps attract water to the upper layer of the skin

More about Saccharomyces/manganese ferment
Riboflavin~0.2–0.75%
Formula
Irritation risk
Low
More about Riboflavin
Phospholipids~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Folic acid~0.2–0.75%
Key active
Irritation risk
Low
Works for
Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid
Enteromorpha compressa extract~0.2–0.75%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Enteromorpha compressa extract
Glycoproteins~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Glycoproteins
Ginkgo biloba leaf extract~0.2–0.75%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-blemishAntibacterialAnti-inflammatory

A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating

More about Ginkgo biloba leaf extract
Serine~0.3–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Proline~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Proline
Alanine~0.3–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Glutamic acid~0.2–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid
Niacinamide~0.15–0.7%
Under-dosed
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Sphingomonas ferment extract~0.15–0.65%
Formula
Sodium phytate~0.15–0.6%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Parfum~0.1–0.5%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Caprylyl glycol~0.15–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Undecylenoyl glycine~0.15–0.65%
Formula
Irritation risk
Low
Works for
Cleansing
More about Undecylenoyl glycine
Ethylhexylglycerin~0.1–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Capryloyl glycine~0.15–0.65%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together, preserve cosmetic products, and attract water to the upper layer of the skin

More about Capryloyl glycine
Ingredient list view

Galactomyces ferment filtrate, Sodium hyaluronate, Oryza sativa bran water, Hyaluronic acid, Zinc hydrolyzed hyaluronate, Hydroxypropyltrimonium hyaluronate, Sodium hyaluronate dimethylsilanol, Sodium hyaluronate crosspolymer, C12-13 alkyl glyceryl hydrolyzed hyaluronate, Hydrolyzed hyaluronic acid, Sodium acetylated hyaluronate, Ascorbyl propyl hyaluronate, Superoxide dismutase, Saccharomyces polypeptides, Unknown, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-5, Palmitoyl tripeptide-1, Acetyl octapeptide-3, Ceramide ns, Saccharomyces/copper ferment, Saccharomyces/zinc ferment, Saccharomyces/manganese ferment, Riboflavin, Phospholipids, Folic acid, Enteromorpha compressa extract, Glycoproteins, Ginkgo biloba leaf extract, Serine, Proline, Alanine, Glutamic acid, Niacinamide, Sphingomonas ferment extract, Sodium phytate, Parfum, Caprylyl glycol, Undecylenoyl glycine, Ethylhexylglycerin, Capryloyl glycine

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Le Mieux Skincare
$70.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Le MieuxTGF-β BOOSTERYOUR PRODUCTUrban Skin RxHydraFirm + Brightening SerumArenciaDeep Water Surge SerumCos De BAHAGN Galactomyces 94 Serum
Match—70%67%67%
Price——$32.72$11.19
Shared key ingredients—5 of 228 of 223 of 22
Key difference—Lactic AcidCopper Tripeptide-1Glycerin
Irritancy Medium Low Medium Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

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Le Mieux TGF-β BOOSTER
Le MieuxTGF-β BOOSTER

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As an Amazon Associate, WIMJ earns from qualifying purchases.