Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Evens skin tone
- Anti-blemish
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"ISNTREE - TW-Real Bifida Ampoule" is effective for: Anti-inflammatory, Moisturizing, Anti-blemish, Anti-aging and Evens skin tone
Ingredient callouts
- A good concentration of Niacinamide (2.00% - 2.90%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Peptides (copper tripeptide-1 0.10% - 0.40%, palmitoyl tripeptide-1 0.15% - 0.65%, acetyl hexapeptide-8 0.10% - 0.45% and palmitoyl tripeptide-1 2.80% - 4.30%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.30% - 0.75%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Humectants (acetyl hexapeptide-8 0.10% - 0.45%, hydrolyzed collagen 0.40% - 0.90%, sodium hyaluronate 0.20% - 0.70%, lactobacillus/rice ferment filtrate 0.35% - 0.85%, arginine 0.35% - 0.80%, glycerin 0.95% - 1.40% and lactobacillus/rice ferment filtrate 3.50% - 5.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
About the brand
According to Cruelty-Free Kitty "ISNTREE" is cruelty free and so is its parent company.
Price
The product retails for 24.50A$ in Australia, for 32.09CA$ in Canada and from 16.32$ up to 19.85$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
This thin, non-sticky formula infused with 88% of concentrated bifida ferment lysate strengthens the skin barrier for elastic skin, smoothing the appearance of wrinkles.
Source: Soko Glam
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, copper tripeptide-1, palmitoyl tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect
Evens skin tone
What does the product description say?
It’s also enriched with Pumpkin Ferment Extract, Soybean Ferment Extract, and Rice Ferment Filtrate to protect skin from external aggressors that can prematurely age skin while brightening and evening skin tone and texture. p H of 6.0 ± 1.0.
Source: Soko Glam
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: bifida ferment lysate, lactobacillus/pumpkin ferment extract.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
An enzyme-based exfoliant
Moisturizing
What does the product description say?
Lightweight but moisturizing water-based formulation is dermatologically tested.
Source: Yesstyle
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
arginine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, hydrolyzed collagen.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, niacinamide, palmitoyl tripeptide-1
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A fermentation product created by bacteria Lactobacillus out of rice. The fermented product helps attract water to the upper layer of the skin. It has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
Anti-oxidation
This product contains antioxidants (bifida ferment lysate) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
A plant extract. Can have an anti-oxidant effect, but can also contain irritants
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
A fermentation product created by bacteria Lactobacillus out of rice. The fermented product helps attract water to the upper layer of the skin. It has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking
A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 ISNTREE TW-Real Bifida Ampoule | Current | $16.32 | |
 Manyo Bifida Biome Complex Ampoule MINI | 81% | $22.90 | |
 SNP Cosmetics SNP PREP - Peptaronic Serum | 81% | $19.99 | |
 MISSHA Time Revolution Night Repair Borabit Ampoule | 78% | $42.50 | |
 NATUREKIND Boosting Bifida Ampoule | 78% | $18.03 | |
Cos De BAHA P M.A Peptide Serum Jumbo | 75% | $14.70 |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
A fermentation product created by bacteria Lactobacillus out of rice. The fermented product helps attract water to the upper layer of the skin. It has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking
A fermentation product created by bacteria Lactobacillus out of rice. The fermented product helps attract water to the upper layer of the skin. It has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Potential irritants
Anise fruit extract. Used as a fragrance. Can be irritating
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
A plant extract. Can have an anti-oxidant effect, but can also contain irritants
A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking
A fermentation product created by bacteria Lactobacillus out of rice. The fermented product helps attract water to the upper layer of the skin. It has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Anise fruit extract. Used as a fragrance. Can be irritating
A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A fermentation product created by bacteria Lactobacillus out of rice. The fermented product helps attract water to the upper layer of the skin. It has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A plant extract. Can have an anti-oxidant effect, but can also contain irritants
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A plant extract that can help neutralize free radicals in skin. It contains a compound salicin that can theoretically be converted into salicylic acid that, in turn, helps reduce inflammation in skin, but the evidence of effectiveness in skin is lacking and the extract is usually not used in a concentration that would enable an exfoliating effect
A fermentation product created by bacteria Lactobacillus out of soybean. The fermented product helps to attract water to the upper layer of the skin and has anti-bacterial properties. It might be helpful in calming down inflammation and could be helpful in evening out skin tone, but studies are lacking
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
Ingredient list view
Bifida ferment lysate, Lactobacillus/pumpkin ferment extract, Lactobacillus/soybean ferment extract, Lactobacillus/rice ferment filtrate, Palmitoyl tripeptide-1, Niacinamide, Bifida ferment lysate, Dipropylene glycol, Niacinamide, Glycerin, 1,2-hexanediol, Butylene glycol, Illicium verum fruit extract, Allantoin panthenol, Unknown, Water, Scutellaria baicalensis root extract, Arginine, Carbomer, Adenosine, Disodium edta, Lactobacillus/rice ferment filtrate, Sodium hyaluronate, Origanum vulgare leaf extract, Chamaecyparis obtusa leaf extract, Hydrolyzed collagen, Salix alba bark extract, Lactobacillus/soybean ferment extract, Lactobacillus/pumpkin ferment extract, Portulaca oleracea extract, Cinnamomum cassia bark extract, Beta-glucan, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Copper tripeptide-1
- Bifidobacterium longumlysate, a new ingredient forreactive skin
- Use of Probiotics for Dermal Applications
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Glycerol and the skin: holistic approach to its origin and functions
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants
- Flavonoids in Treating Psoriasis
- Improvement of skin barrier dysfunction by Scutellaria baicalensis GEOGI extracts through lactic acid fermentation
- Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Efficacy and Safety of White Willow Bark (Salix alba) Extract
- An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging
- Portulaca oleracea (purslane)
- β-Glucans: Multi-Functional Modulator of Wound Healing
- Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucan
- Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Review
- Anticancer properties of low molecular weight oat beta-glucan – An in vitro study
- A critical review on production and industrial applications 2 of beta-glucans
- Improving skin function with CM-glucan, a biological response modifier from yeast
- Preparation, characterization, and biological properties of β-glucans
- Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatus
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds