PRODUCT REVIEW
Isispharma Metroruboril AZ
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Product summary
What can the product work for?
Anti-blemish
azelaic acid
6.6% -
8.1%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
centella asiatica leaf extract
0.15% -
0.25%
Irritation risk:
Concentration: Effectiveness:
LOW
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
niacinamide
0.5% -
0.75%
Irritation risk:
Concentration: Insufficient!
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Evens skin tone
azelaic acid
6.6% -
8.1%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
glycyrrhetinic acid
0.55% -
0.85%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation
niacinamide
0.5% -
0.75%
Irritation risk:
Concentration: Insufficient!
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Anti-aging
centella asiatica leaf extract
0.15% -
0.25%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
niacinamide
0.5% -
0.75%
Irritation risk:
Concentration: Insufficient!
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
caprylic/capric triglyceride
3.3% -
4.1%
Irritation risk:
Concentration: Effectiveness: HIGH
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
glycerin
2.5% -
3%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
polyglyceryl-2 dipolyhydroxystearate
0.7% -
1.05%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps to soften the upper layer of the skin
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Anti-oxidation
glycyrrhetinic acid
0.55% -
0.85%
Irritation risk:
Concentration: Effectiveness: HIGH
Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation
azelaic acid
6.6% -
8.1%
Irritation risk:
Concentration: Effectiveness: HIGH
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
escin
0.3% -
0.6%
Irritation risk:
Concentration: Effectiveness:
LOW
A compound obtained from horse chestnut. It is claimed that this chemical can improve circulation, but there is no evidence available that it works in skin
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Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Evens skin tone | |
| Anti-blemish |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 0
Potential irritants
escin
0.3% -
0.6%
Irritation risk:
Works for:
Anti-oxidation
A compound obtained from horse chestnut. It is claimed that this chemical can improve circulation, but there is no evidence available that it works in skin
calendula officinalis flower extract
0.05% -
0.15%
Irritation risk:
Works for:
Anti-oxidation
A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating
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Comodogenic ingredients
No comodogenic ingredients detected
Similar products & dupes
| Isispharma - Metroruboril AZ |  Cos De BAHA - Azelaic Acid 10% Serum Sponsored | Miss Alice Cosmetics - Azelaica | NINELESS - A-control 10% Azelaic Acid Serum | NINE LESS - A-control 10% Azelaic Acid Serum | Nooance - SOIN CLARIFIANT ANTI-ROUGEURS | Boots - Dermacare Hyperpigmentation Cream | Conscious Chemist - Pigmentation & Dark Spot Corrector Gel Cream |  skinmade - Azelaic Acid + Salicylic Acid serum | Dermatica - Tretinoin, Niacinamide 4%, Azelaic Acid 4% | Cos De BAHA - Azelaic Acid 5% Facial Serum with Niacinamide - Fast Rosacea Skin Care Product + Reduce Cystic Acne Scar + Redness Relief Face + Pimple Pigmentation Blackhead |  Skinfix USA - Acne+ 2% BHA Spot Treatment | |
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| WIMJ similarity score |
78%
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87%
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82%
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78%
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78%
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| Irritancy | IRRITANCY
MEDIUM
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LOW
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MEDIUM
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LOW
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MEDIUM
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LOW
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MEDIUM
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MEDIUM
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LOW
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LOW
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
0.5% -
0.75%
Irritation risk:
Works for:
Anti-aging,
Evens skin tone,
Anti-blemish,
Moisturizing,
Reduces irritation,
Reduces redness,
Anti-inflammatory,
Antibacterial
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
centella asiatica leaf extract
0.15% -
0.25%
Irritation risk:
Works for:
Reduces irritation,
Reduces redness,
Anti-inflammatory,
Anti-aging,
Anti-blemish
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. It can be irritating to sensitive skin. Might be helpful in preventing stretch marks. It could, however, itself be irritating.
Show more
Potential irritants
escin
0.3% -
0.6%
Irritation risk:
Works for:
Anti-oxidation
A compound obtained from horse chestnut. It is claimed that this chemical can improve circulation, but there is no evidence available that it works in skin
calendula officinalis flower extract
0.05% -
0.15%
Irritation risk:
Works for:
Anti-oxidation
A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating
Show more
Comodogenic ingredients
We couldn't find any comodogenic ingredients in this product
All ingredients
azelaic acid
6.6% -
8.1%
Irritation risk:
Works for:
Anti-blemish,
Anti-oxidation,
Evens skin tone,
Exfoliation
Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals
betaine
4.3% -
5.2%
Irritation risk:
Works for:
Moisturizing
Helps attract water to the upper layer of the skin and improves the product texture
Show more
Ingredient list view
Water, Azelaic acid, Betaine, Caprylic/capric triglyceride, Glycerin, Butylene glycol, Pentylene glycol, Vinyl dimethicone/methicone silsesquioxane crosspolymer, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Lauryl glucoside, Polyglyceryl-2 dipolyhydroxystearate, Glycyrrhetinic acid, Niacinamide, Ethylhexylglycerin, Panthenol, Sclerotium gum, Chlorphenesin, Escin, O-cymen-5-ol, Polysorbate 60, Sorbitan isostearate, Ruscus aculeatus root extract, Ammonium glycyrrhizate, Citric acid, Centella asiatica leaf extract, Hydrolyzed yeast protein, Calendula officinalis flower extract, Sodium citrate
Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application
- Effects of topical application of B‐Resorcinol and Glycyrrhetinic acid monotherapy and in combination with fractional CO2 laser treatment for benign hand hyperpigmentation treatment
- 18β-Glycyrrhetinic Acid and Glabridin Prevent Oxidative DNA Fragmentation in UVB-irradiated Human Keratinocyte Cultures
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Final Report on the Safety Assessment of Sodium p-Chloro-m-Cresol, p-Chloro-m-Cresol, Chlorothymol, Mixed Cresols, m-Cresol, o-Cresol, p-Cresol, Isopropyl Cresols, Thymol, o-Cymen-5-ol, and Carvacrol
- Allergic contact dermatitis caused by isopropyl methylphenol, a new hapten
- Centella asiatica in Dermatology: An Overview
- Contact dermatitis due to Madecassol
- Topical application of Calendula officinalis (L.): Formulation and evaluation of hydrophilic cream with antioxidant activity
- The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.)
- Final report on the safety assessment of Calendula officinalis extract and Calendula officinalis