Works for:
based on ingredients and %- Anti-aging
- Anti-oxidation
- Evens skin tone
- Anti-blemish
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"ISDIN - Isdinceutics Rejuvenate A. G. E Reverser Night Cream" has a good moisturizing formula. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (betaine, carnosine, glycerin, sodium hyaluronate crosspolymer and sodium lactate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, caprylic/capric triglyceride, dimethicone and cetyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- We love that this moisturizer contains a good concentration of niacinamide 3.00% - 3.70%. Niacinamide is a perfect active in a moistruizer because it helps calm down inflamation in skin and support the skin barrier. More than that, it is helpful for most common skin concerns: it helps regulat oil production, help reduce acne and clogged pores, improve skin tone and prevent pigmentation marks. It also helps fight photodamage.
- This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.10% - 0.20%) it cannot have a noticeable benefit for the skin.
- This moisturizer also contains Peptides (palmitoyl tetrapeptide-7 0.15% - 0.25% and palmitoyl tripeptide-1 0.15% - 0.25%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 61.78£ in the United Kingdom.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
Isdin Isdinceutics Rejuvenate A.G.E Reverser Night Cream 50ml is a restorative night cream.It is formulated based on Melatonin which stimulates the antioxidant defences, to repair from aggressions suffered during the day and Helichrysum Italicum extracts which stimulates the release of soothing molecules while increasing the well-being sensation.This care helps to correct the signs of photo-ageing, against wrinkles and loss and firmness, while its carnosine content delays the formation of final products of advanced glycation (A.G.E) which can degrade the properties of collagen and elastin.Dermatologically tested. Non comedogenic.
Source: Cocoon Center
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: carnosine, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A compound that can regulate sleep cycles in humans and animals. When used in cosmetics, comes from plant sources. It can work as anti-oxidant in skin when applied topically in skincare
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Anti-oxidation
This product contains antioxidants (carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - melatonin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
A compound that can regulate sleep cycles in humans and animals. When used in cosmetics, comes from plant sources. It can work as anti-oxidant in skin when applied topically in skincare
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Moisturizing
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
betaine, carnosine.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
Attracts water into the upper layer of the skin
Helps attract water to the upper layer of the skin and improves the product texture
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
A peptide. It helps attract water to the upper layer of the skin, support skin's barrier function and might have some slight anti-aging effect through stimulating skin's own production of hyaluronic acid
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Used to improve the product consistency and soften the upper layer of the skin
An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.
Used to preserve products, dissolve other ingredients and create a nice product texture
Used to create a thicker product consistency and soften the upper layer of the skin
Used to create a thicker product consistency and soften the upper layer of the skin
An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
Helps preserve products and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Used to create a nice product consistency
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 ISDIN Isdinceutics Rejuvenate A.G.E Reverser Night Cream | Current | $61.78 | |
CeraVe Eye Cream for Wrinkles | Under Eye Cream with Caffeine, Peptides, Hyaluronic Acid, Niacinamide, and Ceramides for Fine Lines | Fragrance Free & Ophthalmologist Tested |0.5 Ounces | 79% | $33.99 | |
Dermatica Nourishing Ceramide + Peptides | 78% | $-1.00 | |
 e.l.f. Cosmetics Happy Hydration Cream | 77% | $-1.00 | |
 NEOGEN X SUR.MEDIC V.Biome Advanced Eye Cream | 76% | $24.50 | |
Transparent Lab Niacinamide Glow Cream | 74% | $15.95 |
Key Actives
Potential irritants
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
Ingredient list view
Water, Glycerin, Propanediol, Niacinamide, Betaine, Olus oil, Vegetable oil, Caprylic/capric triglyceride, Silica, Dimethicone, Hydrogenated polyisobutene, Isodecyl neopentanoate, Octyldodecanol, Stearyl alcohol, Dipentaerythrityl hexacaprylate/hexacaprate, Tridecyl trimellitate, Alcohol denat., Butylene glycol, Phenylpropanol, Ammonium acryloyldimethyltaurate/vp copolymer, Panthenol, Tocopheryl acetate, Acrylates/c10-30 alkyl acrylate crosspolymer, Caprylyl glycol, Tridecyl stearate, Carnosine, Parfum, Neopentyl glycol dicaprylate/dicaprate, Melatonin, Cetyl alcohol, Glyceryl stearate, Pentylene glycol, Sodium hyaluronate crosspolymer, Disodium edta, Peg-75 stearate, Peg-8, Carbomer, Polysorbate 20, Sodium lactate, Ceteth-20, Steareth-20, Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, Tocopherol, Ascorbyl palmitate, Magnesium chloride, Helichrysum italicum extract, Ascorbic acid, Citric acid, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Ci 15985, Ci 19140
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Amended Safety Assessment of Alkyl Esters as Used in Cosmetics
- Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care products
- [Melatonin in dermatology. Experimental and clinical aspects]
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Analysis of Dyes in Cosmetics: Challenges and Recent Developments