ISDIN Isdinceutics Prevent Hyaluronic Moisture Oily and Combination Skin

ISDIN Isdinceutics Prevent Hyaluronic Moisture Oily and Combination Skin

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
Urea, Panthenol + 17 more
Strong evidence
What the product description says
“Isdinceutics Prevent Hyaluronic Moisture Oily and Combination Skin”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hydrolyzed hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol, urea

Alteromonas ferment extractKey activeEffect: HighA marine extract that helps attract water to the upper layer of the skin. It is claimed to have anti-inflammatory properties but research is lacking~0.2–0.4%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.3–1.5%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.4–0.6%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.35–0.65%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.4–1.7%
Alpha-glucan oligosaccharideKey activeEffect: HighHelps attract water to the upper layer of the skin~1.7–2.1%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~6.4–7.8%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–5.1%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.2–0.4%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
Dimethicone crosspolymerKey activeEffect: MediumUsed to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface~0.25–0.45%
Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.25–0.5%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.65–1%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.3–0.6%
AlginEffect: LowUsed to thicken product formulation. Can help attract water to the upper layer of the skin~0.2–0.35%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.6–0.9%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.7%
Anti-aging
Niacinamide, Serine + 1 more
Strong evidence
What the product description says
“The skin is refreshed, balanced and moisturised.It associates Tri-Moisture Complex, a combination of medium and low molecular weight hyaluronic acid and Pro-Vitamin B5, a hydrating polymer complex, for intense, long-lasting hydration.Multi-Protection Complex, based on Vitamin E, Exo-P and Vit A Tech, which offers antioxidant, anti-pollution and anti-aging protection.Matte-Complex, ingredients based on natural sugars which rebalance the skin flora and help control the appearance of imperfections on the skin.”
Source: Cocoon Center

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: serine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.7%
Anti-blemish
Not advertised by the brand · Niacinamide
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
Evens skin tone
Not advertised by the brand · Niacinamide
Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 9 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.3–0.5%est.
PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.15–0.3%est.
Ci 19140A yellow dyeHigh~0.05–0.1%est.
1,2-hexanediolA preservativeMedium~0.7–1.05%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.6–0.9%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.45–0.65%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.35–0.65%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.3–0.6%est.
Ci 42090A colorant (dye)Medium~0.05–0.1%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
AlginUsed to thicken product formulation. Can help attract water to the upper layer of the skin3/5~0.2–0.35%est.
Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~0.25–0.5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Dimethicone~6.4–7.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glycerin~4.2–5.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Niacinamide~3.1–3.8%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Silica~2.5–3%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
1,2-hexanediol~0.7–1.05%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Alpha-glucan oligosaccharide~1.7–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Alpha-glucan oligosaccharide
Panthenol~1.4–1.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Squalane~1.3–1.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Ammonium acryloyldimethyltaurate/vp copolymer~0.9–1.1%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Butylene glycol~0.65–1%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Caprylyl glycol~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sodium acrylates crosspolymer-2~0.5–0.75%
Formula
Tocopherol~0.45–0.7%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Tocopheryl acetate~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Trehalose~0.4–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Urea~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Acrylates/c10-30 alkyl acrylate crosspolymer~0.35–0.65%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Parfum~0.3–0.5%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Pentylene glycol~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Vigna aconitifolia seed extract~0.25–0.45%
Formula
Lens esculenta seed extract~0.25–0.5%
Formula
Dimethicone crosspolymer~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface

More about Dimethicone crosspolymer
Hydrogenated vegetable oil~0.25–0.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil
Maltodextrin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Tetrasodium glutamate diacetate~0.25–0.45%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Hydrolyzed hyaluronic acid~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Serine~0.2–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Sodium hydroxide~0.2–0.4%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Xanthan gum~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Alteromonas ferment extract~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

A marine extract that helps attract water to the upper layer of the skin. It is claimed to have anti-inflammatory properties but research is lacking

More about Alteromonas ferment extract
Algin~0.2–0.35%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Used to thicken product formulation. Can help attract water to the upper layer of the skin

More about Algin
Disodium phosphate~0.2–0.35%
Formula
Irritation risk
Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate
Glyceryl polyacrylate~0.15–0.3%
Formula
Irritation risk
Low

Helps to create a nice product texture and spread the product more easily on the skin

More about Glyceryl polyacrylate
Pullulan~0.15–0.3%
Irritant · high
Irritation risk
High
Works for
Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium phosphate~0.1–0.2%
Formula
Irritation risk
Low

Helps regulate the pH of the formulation

More about Potassium phosphate
Ci 19140~0.05–0.1%
Irritant · high
Irritation risk
High

A yellow dye

More about Ci 19140
Ci 42090~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A colorant (dye)

More about Ci 42090
Ingredient list view

Water, Dimethicone, Glycerin, Niacinamide, Silica, 1,2-hexanediol, Alpha-glucan oligosaccharide, Panthenol, Squalane, Ammonium acryloyldimethyltaurate/vp copolymer, Butylene glycol, Caprylyl glycol, Sodium acrylates crosspolymer-2, Tocopherol, Tocopheryl acetate, Trehalose, Urea, Acrylates/c10-30 alkyl acrylate crosspolymer, Parfum, Pentylene glycol, Vigna aconitifolia seed extract, Lens esculenta seed extract, Dimethicone crosspolymer, Hydrogenated vegetable oil, Maltodextrin, Sodium hyaluronate, Tetrasodium glutamate diacetate, Hydrolyzed hyaluronic acid, Serine, Sodium hydroxide, Xanthan gum, Alteromonas ferment extract, Algin, Disodium phosphate, Glyceryl polyacrylate, Pullulan, Sodium benzoate, Potassium phosphate, Ci 19140, Ci 42090

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Cocoon Center
≈ $42.58
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Amazon UKPrice as of 10/17/2026 21:26 GMT
≈ $60.93
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ISDINIsdinceutics Prevent Hyaluronic Moisture Oily and Combination SkinYOUR PRODUCTIsdinceuticsHyaluronic Moisture Oily and Combination SkinCetaphilRestoring Water GelSimpleX Kindness Hydrating Light Facial Moisturiser
Match—99%92%86%
Price$42.64—$18.82−$23.82$2.63−$40.01
Shared key ingredients—14 of 1410 of 146 of 14
Key difference——AnhydroxylitolMineral Oil
Irritancy Medium Medium Low Low
Drying alcohol————
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Product summary

"ISDIN - Isdinceutics Prevent Hyaluronic Moisture Oily and Combination Skin" is a well-rounded moisturizing product. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Panthenol, urea, glycerin, hydrolyzed hyaluronic acid and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (dimethicone, squalane, hydrogenated vegetable oil, caprylyl glycol and pentylene glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We particularly like that there is a good concentration of Niacinamide (3.10% - 3.80%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
  • Panthenol (pro-vitamin B5) at about 1.40% - 1.70% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 31.90£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

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ISDIN Isdinceutics Prevent Hyaluronic Moisture Oily and Combination Skin
ISDINIsdinceutics Prevent Hyaluronic Moisture Oily and Combination Skin

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As an Amazon Associate, WIMJ earns from qualifying purchases.