Works for:
based on ingredients and %- Moisturizing
- Anti-oxidation
- Anti-aging
- Anti-blemish
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 2
Key actives
Product Summary
Based on the ingredients included, "iS Clinical - Reparative Moisture Emulsion" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Urea, cyclomethicone, glycerin, sodium hyaluronate and glucose in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (tripeptide-1, cyclomethicone, ethyl linoleate, glycosaminoglycans and caprylic/capric triglyceride) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- this moisturizer includes a form of retinoids (vitamin A) - retinyl palmitate 0.15% - 0.30%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
- This moistruizer also contains peptides (tripeptide-1 0.30% - 0.60% and tripeptide-10 citrulline 0.30% - 0.55%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 105.00$ in the United States, for 251.72A$ in Australia and from 61.02£ up to 84.00£ in the United Kingdom.
For a detailed price comparison: click here.
Works for
Anti-oxidation
This product contains antioxidants (ethylbisiminomethylguaiacol manganese chloride, superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin
A plant extract that if used in high concentration might help to neutralize free radicals in skin
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
A plant extract that might have some antioxidant properties, but mostly used in cosmetics for its color
Moisturizing
What does the product description say?
Reparative Moisture Emulsion
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
cyclomethicone, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: tripeptide-1, tripeptide-10 citrulline, urea
Helps attract water to the upper layer of the skin and may help reduce inflammation in skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Helps reduce acne and blemishes. Helps to soften the upper layer of the skin and reduce inflammation. Might be helpful in reducing hyperpigmentation and evening out the skin tone, but evidence of effectiveness in skin are lacking
Yeast extract. Helps attract water to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Long sugars that help attract water to the upper layer of the skin
A stable oil-soluble derivative of vitamin B5. It can help support skin barrier and reduce inflammation in skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
Helps preserve products and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Anti-aging
What does the product description say?
The addition of copper tripeptide growth factor helps to reduce fine lines and wrinkles by stimulating collagen production.
Source: Skinstore
This product contains tripeptide-1, tripeptide-10 citrulline. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness
A stable oil-soluble derivative of vitamin B5. It can help support skin barrier and reduce inflammation in skin
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Anti-blemish
This product might be able to help reduce blemishes and clogged pores because it contains ethyl linoleate.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: pantothenic acid
Helps reduce acne and blemishes. Helps to soften the upper layer of the skin and reduce inflammation. Might be helpful in reducing hyperpigmentation and evening out the skin tone, but evidence of effectiveness in skin are lacking
Helps attract water to the upper layer of the skin and may help reduce inflammation in skin
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-oxidation | |
| Moisturizing | |
| Anti-aging |
Total Promises Fulfilled score: 91/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 iS Clinical Reparative Moisture Emulsion | Current | $84.00 | |
Panthenol extra Face and Eye Cream | 44% | $11.39 | |
Neogenisis Barrier Renewal Cream | 43% | $9.50 | |
 Altruist Moisturising Fluid 0.5% Hyaluronic Acid | 42% | $6.00 | |
 LightStim for Wrinkles White | 42% | $186.75 | |
 Maruderm Hyaluronic Acid Moisturizer Face & Body Cream | 40% | - |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Sodium hyaluronate, Glycerin, Squalane, Caprylic/capric triglyceride, Beta vulgaris root extract, Beta vulgaris, Haberlea rhodopensis leaf extract, Faex extract, Yeast extract, Tocopherol, Panthenyl triacetate, Ethyl linoleate, Butylene glycol, Acetyl tyrosine, Proline, Hydrolyzed vegetable protein, Hydrolyzed soy protein, Tripeptide-10 citrulline, Tripeptide-1, Lecithin, Xanthan gum, Carbomer, Triethanolamine, Glycosaminoglycans, Urea, Glucose, Guanidine hcl, Cetearyl alcohol, Ceteareth-20, Dimethicone, Dipalmitoyl hydroxyproline, Cyclomethicone, Polysorbate 40, Superoxide dismutase, Pvp, Panthenol, Phospholipids, Retinyl palmitate, Tocopheryl acetate, Ascorbyl palmitate, Pantothenic acid, Ethylbisiminomethylguaiacol manganese chloride, 1,2-hexanediol, Caprylyl glycol, Disodium edta
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Glycerol and the skin: holistic approach to its origin and functions
- Skin benefits of a myconoside-rich extract from resurrection plant Haberlea rhodopensis
- The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transfer
- Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitamins
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Panthenyl Triacetate Transformation, Stimulation of Metabolic Pathways, and Wound-Healing Properties in the Human Skin
- Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway
- Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris
- Extracts from Glycine max (soybean) induce elastin synthesis and inhibit elastase activity
- Dermatological and cosmeceutical benefits of Glycine max (soybean) and its active components
- Safety Assessment of Soy Peptides as Used in Cosmetics
- Topical urea in skincare: A review
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- A novel efficient and safe treatment for atopic dermatitis: Topical superoxide dismutase (SOD).
- Novel topical agent containing superoxide dismutase 100 000 IU and 4% of plant extracts as a mono-therapy for atopic dermatitis
- Copper/Zinc Superoxide Dismutase in Human Skin: Current Knowledge
- Photoprotective Effect of Topically Applied Superoxide Dismutase on Sunburn Reaction in Comparison with Sunscreen
- The role of superoxide dismutase (SOD) in skin disorders
- Topical formulations with superoxide dismutase: Influence of formulation composition on physical stability and enzymatic activity
- Skin protective effects of RM191A, a novel superoxide dismutase mimetic
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- A Synthetic Superoxide Dismutase/Catalase Mimetic (EUK-134) Inhibits Membrane-Damage-Induced Activation of Mitogen-Activated Protein Kinase Pathways and Reduces p53 Accumulation in Ultraviolet B-Exposed Primary Human Keratinocytes
- Use of the synthetic superoxide dismutase/catalase mimetic EUK-134 to compensate for seasonal antioxidant deficiency by reducing pre-existing lipid peroxides at the human skin surface
- A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols